{"id":359,"date":"2026-08-07T09:00:00","date_gmt":"2026-08-07T09:00:00","guid":{"rendered":"https:\/\/all-cancers.com\/cancer\/gestational-trophoblastic-disease-gtd-cancer-types\/"},"modified":"2026-10-29T13:38:05","modified_gmt":"2026-10-29T13:38:05","slug":"gestational-trophoblastic-disease-gtd-cancer-types","status":"publish","type":"cancer_type","link":"https:\/\/all-cancers.com\/zh-hk\/cancer\/gestational-trophoblastic-disease-gtd-cancer-types\/","title":{"rendered":"\u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5 (GTD)"},"content":{"rendered":"<div class=\"ac-blog-article\">\n<p class=\"ac-blog-lead\"><strong>\u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5 (GTD) \u63cf\u8ff0\u4e86\u4e00\u7d44\u6e90\u81ea\u80ce\u76e4\u7d44\u7e54\u7684\u7f55\u898b\u816b\u7624\uff0c\u7279\u5225\u662f\u6e90\u81ea\u6ecb\u990a\u5c64\u7d30\u80de\u3002\u6ecb\u990a\u5c64\u7d30\u80de\u901a\u5e38\u5728\u61f7\u5b55\u671f\u9593\u6703\u767c\u80b2\u6210\u80ce\u76e4\uff0c\u5e6b\u52a9\u6ecb\u990a\u80da\u80ce\u3002\u7136\u800c\uff0c\u6ecb\u990a\u5c64\u7d30\u80de\u7684\u7570\u5e38\u53ef\u80fd\u5c0e\u81f4\u751f\u9577\u4e0d\u53d7\u63a7\u5236\uff0c\u5f62\u6210\u816b\u7624\u6216\u56ca\u816b\uff0c\u4e26\u5f15\u767c\u598a\u5a20\u6ecb\u990a\u5c64\u75be\u75c5 (GTD)\u3002<\/strong><\/p>\n<nav class=\"ac-blog-toc\" aria-label=\"\u672c\u6587\u5c0e\u89bd\">\n<p><strong>\u672c\u6587\u5c0e\u89bd<\/strong><\/p>\n<ul>\n<li><a href=\"#what-is-gestational-trophoblastic-disease-gtd\">\u4ec0\u9ebc\u662f\u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5 (GTD)\uff1f<\/a><\/li>\n<li><a href=\"#causes-and-risk-factors-of-gestational-trophoblastic-disease-gtd\">\u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5 (GTD) \u7684\u539f\u56e0\u548c\u5371\u96aa\u56e0\u5b50<\/a><\/li>\n<li><a href=\"#symptoms-of-gestational-trophoblastic-disease-gtd\">\u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5 (GTD) \u7684\u75c7\u72c0<\/a><\/li>\n<li><a href=\"#stages-of-gestational-trophoblastic-disease-gtd-and-survival-rates\">\u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5 (GTD) \u7684\u968e\u6bb5\u548c\u5b58\u6d3b\u7387<\/a><\/li>\n<li><a href=\"#limitations-of-traditional-therapies-for-gestational-trophoblastic-disease-gtd\">\u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5 (GTD) \u50b3\u7d71\u7642\u6cd5\u7684\u5c40\u9650\u6027<\/a><\/li>\n<\/ul>\n<\/nav>\n<h2 id=\"what-is-gestational-trophoblastic-disease-gtd\">\u4ec0\u9ebc\u662f <strong>\u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5 (GTD)<\/strong>?<\/h2>\n<p>\u4e86\u89e3\u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5 (GTD) \u9700\u8981\u8a8d\u8b58\u5230\u5176\u8461\u8404\u7cd6\u4ee3\u8b1d\u589e\u5f37\u7684\u7368\u7279\u751f\u7269\u5b78\u7279\u5fb5\u3002\u8207\u5176\u4ed6\u60e1\u6027\u816b\u7624\u975e\u5e38\u76f8\u4f3c\uff0cGTD \u7d30\u80de\u8868\u73fe\u51fa\u5c0d\u7cd6\u9175\u89e3\u7684\u6975\u5ea6\u4f9d\u8cf4\uff08\u9019\u7a2e\u73fe\u8c61\u6700\u521d\u88ab\u7a31\u70ba Warburg \u6548\u61c9\uff09\uff0c\u6d88\u8017\u8461\u8404\u7cd6\u7684\u901f\u5ea6\u662f\u6b63\u5e38\u7d30\u80de\u4e2d\u89c0\u5bdf\u5230\u7684\u901f\u5ea6\u7684 200 \u500d\u3002<\/p>\n<p>\u5728\u5168\u7403\u7bc4\u570d\u5167\uff0c\u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5 (GTD) \u5927\u7d04\u6bcf 1,000 \u4f8b\u598a\u5a20\u4e2d\u5c31\u6709 1 \u4f8b\u767c\u751f\uff0c\u6d89\u53ca\u591a\u7a2e\u4e9e\u578b\uff0c\u5305\u62ec\u8461\u8404\u80ce\uff08\u5b8c\u5168\u6027\u548c\u90e8\u5206\u6027\uff09\u3001\u4fb5\u8972\u6027\u8461\u8404\u80ce\u3001\u7d68\u6bdb\u819c\u764c\u548c\u80ce\u76e4\u90e8\u4f4d\u6ecb\u990a\u7d30\u80de\u816b\u7624\u3002\u7136\u800c\uff0c\u5730\u5340\u5dee\u7570\u666e\u904d\u5b58\u5728\uff0c\u7279\u5225\u662f\u5728\u9999\u6e2f\u548c\u4e9e\u6d32\u5176\u4ed6\u5730\u5340\uff0cGTD \u5728\u9019\u4e9b\u5730\u5340\u7684\u89c0\u5bdf\u66f4\u70ba\u983b\u7e41\u3002<\/p>\n<p>\u5728\u9999\u6e2f\uff0c\u6bcf 10,000 \u6b21\u61f7\u5b55\u4e2d\u5927\u7d04\u6709 6 \u6b21\u767c\u751f\u3002\u9019\u7a2e\u767c\u75c5\u7387\u7684\u589e\u52a0\u53ef\u80fd\u53cd\u6620\u4e86\u4e9e\u6d32\u4eba\u7fa4\u7279\u6709\u7684\u907a\u50b3\u50be\u5411\u548c\u6d41\u884c\u75c5\u5b78\u7279\u5fb5\u3002 AllCancer \u5df2\u5efa\u7acb\u7684\u5c08\u696d\u77e5\u8b58\u4fc3\u9032\u4e86\u8d85\u904e 12,000 \u4f8b\u764c\u75c7\u75c5\u4f8b\u7684\u6cbb\u7642\uff0c\u5728\u7ba1\u7406\u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5 (GTD) \u65b9\u9762\u63d0\u4f9b\u4e86\u7121\u8207\u502b\u6bd4\u7684\u7d93\u9a57\uff0c\u6700\u7d42\u4f7f\u5b55\u7522\u5a66\u5065\u5eb7\u6210\u70ba\u512a\u5148\u95dc\u6ce8\u7684\u7126\u9ede\u3002<\/p>\n<p>\u5728\u60c5\u7dd2\u548c\u8eab\u9ad4\u4e0a\uff0c\u53d7\u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5 (GTD) \u5f71\u97ff\u7684\u60a3\u8005\u6703\u51fa\u73fe\u4e0d\u540c\u7684\u75c7\u72c0\u3002\u5e38\u898b\u7684\u8eab\u9ad4\u8868\u73fe\u5305\u62ec\uff1a<\/p>\n<ul>\n<li>\u4e0d\u898f\u5247\u9670\u9053\u51fa\u8840\uff08\u5e38\u88ab\u8aa4\u8a8d\u70ba\u6d41\u7522\u6216\u6708\u7d93\u4e0d\u898f\u5247\uff09<\/li>\n<li>\u9aa8\u76c6\u4e0d\u9069\u548c\u75d9\u6523<\/li>\n<li>\u56b4\u91cd\u5641\u5fc3\u548c\u5614\u5410\uff08\u5614\u5410\uff09<\/li>\n<li>\u5b50\u5bae\u5feb\u901f\u589e\u5927\u8d85\u51fa\u57fa\u65bc\u80ce\u9f61\u7684\u9810\u671f<\/li>\n<\/ul>\n<p>\u5f9e\u5fc3\u7406\u4e0a\u4f86\u8aaa\uff0c\u88ab\u8a3a\u65b7\u51fa\u60a3\u6709\u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5 (GTD) \u7684\u5973\u6027\u53ef\u80fd\u6703\u7d93\u6b77\u5de8\u5927\u7684\u58d3\u529b\u3001\u7126\u616e\u4ee5\u53ca\u5c0d\u751f\u6b96\u5065\u5eb7\u548c\u672a\u4f86\u61f7\u5b55\u7684\u6050\u61fc\uff0c\u56e0\u6b64\u9700\u8981\u5bcc\u6709\u540c\u60c5\u5fc3\u7684\u5c08\u5bb6\u8b77\u7406\u3002<\/p>\n<h3 id=\"gestational-trophoblastic-disease-gtd-in-asia-unique-epidemiological-insights\">\u4e9e\u6d32\u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5 (GTD)\uff1a\u7368\u7279\u7684\u6d41\u884c\u75c5\u5b78\u898b\u89e3<\/h3>\n<p>\u9999\u6e2f\u7684\u7814\u7a76\u5f37\u8abf\u7368\u7279\u7684\u6d41\u884c\u75c5\u5b78\u6a21\u5f0f\uff0c\u986f\u793a\u4e9e\u6d32\u4eba\u7fa4\u53ef\u80fd\u5177\u6709\u5f71\u97ff\u6ecb\u990a\u7d30\u80de\u75be\u75c5\u76db\u884c\u7387\u7684\u907a\u50b3\u548c\u4ee3\u8b1d\u6613\u611f\u6027\u3002\u6709\u8b49\u64da\u8868\u660e\uff0cGTD \u816b\u7624\u4e2d\u7368\u7279\u7684\u5206\u5b50\u7279\u5fb5\u53ef\u80fd\u8207\u4ee3\u8b1d\u8106\u5f31\u6027\uff08\u5305\u62ec\u8461\u8404\u7cd6\u548c\u8c37\u6c28\u9170\u80fa\u4f9d\u8cf4\u6027\uff09\u986f\u8457\u76f8\u4e92\u4f5c\u7528\uff0c\u9019\u8868\u660e\u4e86\u5275\u65b0\u7684\u6cbb\u7642\u89d2\u5ea6\u3002<\/p>\n<p>\u5728 AllCancer\uff0c\u5c16\u7aef\u7642\u6cd5\u5c07\u9019\u4e9b\u4ee3\u8b1d\u8106\u5f31\u6027\u878d\u5165\u7a81\u7834\u6027\u7642\u6cd5\u4e2d\uff0c\u5305\u62ec\u7a81\u7834\u6027\u7684 HK \u4ee3\u8b1d\u7642\u6cd5\u3002\u8a72\u7b56\u7565\u59cb\u7d42\u8868\u73fe\u51fa\u4ee4\u4eba\u9f13\u821e\u7684\u7de9\u89e3\u7387\uff0c\u6574\u9ad4\u7de9\u89e3\u7387 (ORR) \u70ba 68.7%\uff0c\u51f8\u986f\u4e86\u8a72\u7642\u6cd5\u5728\u6cbb\u7642\u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5 (GTD) \u65b9\u9762\u7684\u8b8a\u9769\u80fd\u529b\u3002<\/p>\n<p><a href=\"\/zh-hk\/treatment-cancer\/\">\u4e86\u89e3\u9769\u547d\u6027\u7684 HK \u4ee3\u8b1d\u7642\u6cd5\u5982\u4f55\u6539\u8b8a\u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5 (GTD) \u7684\u6cbb\u7642\u65b9\u6848\u3002<\/a><\/p>\n<h2 id=\"causes-and-risk-factors-of-gestational-trophoblastic-disease-gtd\">\u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5 (GTD) \u7684\u539f\u56e0\u548c\u5371\u96aa\u56e0\u5b50<\/h2>\n<p>\u4e86\u89e3\u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5 (GTD) \u80cc\u5f8c\u7684\u6f5b\u5728\u539f\u56e0\u548c\u98a8\u96aa\u56e0\u7d20\u70ba\u9810\u9632\u548c\u65e9\u671f\u6aa2\u6e2c\u63d0\u4f9b\u4e86\u91cd\u8981\u7684\u898b\u89e3\u3002\u67d0\u4e9b\u907a\u50b3\u3001\u74b0\u5883\u548c\u751f\u6d3b\u65b9\u5f0f\u56e0\u7d20\u53ef\u80fd\u6703\u589e\u52a0\u500b\u4eba\u98a8\u96aa\uff0c\u9019\u51f8\u986f\u4e86\u500b\u4eba\u548c\u91ab\u7642\u4fdd\u5065\u5f9e\u696d\u8005\u4fdd\u6301\u77e5\u60c5\u8b66\u89ba\u7684\u50f9\u503c\u3002<\/p>\n<h3 id=\"genetic-factors-of-gestational-trophoblastic-disease-gtd\">\u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5 (GTD) \u7684\u907a\u50b3\u56e0\u7d20<\/h3>\n<p>\u96d6\u7136\u8207 GTD \u660e\u986f\u76f8\u95dc\u7684\u7279\u5b9a\u907a\u50b3\u57fa\u56e0\u5f88\u5c11\u898b\uff0c\u4f46\u57fa\u56e0\u7d44\u7814\u7a76\u5f37\u8abf\u4e86\u8207 GTD \u4e9e\u578b\u76f8\u95dc\u7684\u67d3\u8272\u9ad4\u7570\u5e38\u3002\u4f8b\u5982\uff0c\u5b8c\u5168\u8461\u8404\u80ce\u5e38\u5e38\u662f\u7531\u7236\u672c\u57fa\u56e0\u7d44\u91cd\u8907\u5f15\u8d77\u7684\uff0846XX\u6838\u578b\uff0c\u5b8c\u5168\u7236\u672c\u8d77\u6e90\uff09\u3002\u76f8\u53cd\uff0c\u90e8\u5206\u8461\u8404\u80ce\u901a\u5e38\u8868\u73fe\u51fa\u4e09\u500d\u9ad4\u6838\u578b\uff0869 \u689d\u67d3\u8272\u9ad4\uff09\uff0c\u6df7\u5408\u4e86\u6bcd\u672c\u548c\u7236\u672c\u7269\u8cea\u3002<\/p>\n<h3 id=\"metabolic-vulnerabilities-in-gestational-trophoblastic-disease-gtd\">\u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5 (GTD) \u4e2d\u7684\u4ee3\u8b1d\u8106\u5f31\u6027<\/h3>\n<p>\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0cGTD \u7d30\u80de\u5c0d\u8461\u8404\u7cd6\u651d\u53d6\u7684\u7570\u5e38\u4f9d\u8cf4\u4ee3\u8868\u4e86\u6a19\u9776\u6cbb\u7642\u7684\u4e3b\u8981\u4ee3\u8b1d\u5f31\u9ede\u3002\u9019\u4e9b\u6ecb\u990a\u5c64\u7d30\u80de\u8868\u73fe\u51fa\u985e\u4f3c\u74e6\u723e\u5821\u6548\u61c9\u7684\u7279\u5fb5\uff0c\u512a\u5148\u5feb\u901f\u3001\u5927\u91cf\u5730\u6d88\u8017\u8461\u8404\u7cd6\uff0c\u52a0\u901f\u751f\u9577\u4e26\u4fc3\u9032\u60e1\u6027\u9032\u5c55\u3002<\/p>\n<ul>\n<li>\u8461\u8404\u7cd6\u8f49\u904b\u86cb\u767d (GLUT1) \u7684\u904e\u5ea6\u8868\u73fe\u53ef\u52a0\u901f\u8461\u8404\u7cd6\u651d\u53d6\u3002<\/li>\n<li>\u7cd6\u89e3\u6d3b\u6027\u589e\u5f37\uff0c\u78ba\u4fdd\u7d30\u80de\u5feb\u901f\u751f\u9577\u3002<\/li>\n<\/ul>\n<h3 id=\"environmental-lifestyle-factors\">\u74b0\u5883\u548c\u751f\u6d3b\u65b9\u5f0f\u56e0\u7d20<\/h3>\n<p>\u96d6\u7136\u7814\u7a76\u4ecd\u5728\u9032\u884c\u4e2d\uff0c\u4f46\u67d0\u4e9b\u56e0\u7d20\u8207\u98a8\u96aa\u6216\u767c\u75c5\u7387\u589e\u52a0\u6709\u95dc\uff1a<\/p>\n<ul>\n<li>\u5148\u524d\u7684\u8461\u8404\u80ce\u598a\u5a20\u6703\u986f\u8457\u589e\u52a0\u96a8\u5f8c\u61f7\u5b55\u7684\u5fa9\u767c\u98a8\u96aa\u3002<\/li>\n<li>\u7522\u5a66\u6975\u7aef\u5e74\u9f61\uff08\u9752\u5c11\u5e74\u548c 35 \u6b72\u4ee5\u4e0a\uff09\u3002<\/li>\n<li>\u98f2\u98df\u7f3a\u4e4f\u53ef\u80fd\u8207\u4e9e\u6d32\u90e8\u5206\u5730\u5340\u7684\u5340\u57df\u71df\u990a\u8da8\u52e2\u6709\u95dc\u3002<\/li>\n<\/ul>\n<p>\u5728\u9999\u6e2f\u548c\u66f4\u5ee3\u6cdb\u7684\u4e9e\u592a\u5730\u5340\uff0c\u8449\u9178\u548c\u80e1\u863f\u8514\u7d20\u651d\u53d6\u91cf\u8f03\u4f4e\u7684\u98f2\u98df\u6a21\u5f0f\u53ef\u80fd\u662f\u5c0e\u81f4 GTD \u98a8\u96aa\u7684\u6f5b\u5728\u56e0\u7d20\uff0c\u5118\u7ba1\u7814\u7a76\u4ecd\u5728\u9032\u884c\u4e2d\u3002<\/p>\n<h3 id=\"importance-of-early-detection-and-preventative-screening-in-hong-kong\">\u9999\u6e2f\u65e9\u671f\u767c\u73fe\u8207\u9810\u9632\u6027\u7be9\u6aa2\u7684\u91cd\u8981\u6027<\/h3>\n<p>\u65e9\u671f\u7be9\u6aa2\u5728\u6e1b\u5c11 GTD \u76f8\u95dc\u4f75\u767c\u75c7\u65b9\u9762\u5177\u6709\u986f\u8457\u512a\u52e2\u3002\u5b9a\u671f\u7522\u524d\u7be9\u6aa2\u3001\u03b2-\u4eba\u985e\u7d68\u6bdb\u819c\u4fc3\u6027\u817a\u6fc0\u7d20 (\u03b2-hCG) \u76e3\u6e2c\u4ee5\u53ca\u53ca\u6642\u7684\u8d85\u97f3\u6ce2\u8a3a\u65b7\u69cb\u6210\u4e86\u65e9\u671f\u6aa2\u6e2c\u548c\u4ecb\u5165\u7684\u5bf6\u8cb4\u7b56\u7565\u3002<\/p>\n<p><a href=\"\/zh-hk\/our-hospital\/\">\u9810\u7d04\u65e9\u671f\u7be9\u6aa2\u4e26\u63a2\u7d22\u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5 (GTD) \u7684\u7d9c\u5408\u8a3a\u65b7\u3002<\/a><\/p>\n<h3 id=\"empowering-patients-through-advanced-treatments\">\u900f\u904e\u5148\u9032\u7684\u6cbb\u7642\u8ce6\u4e88\u60a3\u8005\u529b\u91cf<\/h3>\n<p>AllCancer \u7684\u958b\u5275\u6027\u7814\u7a76\u5f97\u5230\u4e86 MD \u5b89\u5fb7\u68ee\u7b49\u6b0a\u5a01\u6a5f\u69cb\u7684\u8a8d\u53ef\uff0c\u4e26\u5f97\u5230\u4e86\u674e\u570b\u83ef\u535a\u58eb\u7b49\u5168\u7403\u77e5\u540d\u5148\u9a45\u4ee5\u53ca Semenza \u548c Allison \u7b49\u8afe\u8c9d\u723e\u734e\u7372\u5f97\u8005\u7684\u652f\u6301\uff0c\u5f37\u8abf\u4e86\u61c9\u5c0d GTD \u7684\u5bcc\u6709\u540c\u60c5\u5fc3\u4e14\u7a4d\u6975\u4e3b\u52d5\u7684\u65b9\u6cd5\u3002 HK Metabolic Therapy \u555f\u52d5\u4e86\u7a81\u7834\u6027\u7684\u81e8\u5e8a\u958b\u767c\uff0c\u6b63\u5728\u91cd\u5851\u764c\u75c7\u8b77\u7406\uff0c\u52aa\u529b\u5c07 GTD \u7ba1\u7406\u8f49\u8b8a\u70ba\u7a69\u5b9a\u7684\u6162\u6027\u75c5\u3002<\/p>\n<p>AllCancer \u81f4\u529b\u65bc\u60a3\u8005\u798f\u7949\uff0c\u63a1\u7528\u900f\u904e\u5ee3\u6cdb\u7814\u7a76\u548c\u5168\u7403\u81e8\u5e8a\u7814\u7a76\u57f9\u80b2\u7684\u65b0\u7a4e\u6cbb\u7642\u65b9\u6cd5\uff0c\u9ad4\u73fe\u4e86\u6211\u5011\u7684\u6838\u5fc3\u627f\u8afe\uff1a\u5148\u6cbb\u6108\uff0c\u5f8c\u4ed8\u8cbb\u3002<\/p>\n<p>\u95b1\u8b80 Jane \u7ba1\u7406 GTD \u8a3a\u65b7\u548c\u6210\u529f\u6cbb\u7642\u7d50\u679c\u7684\u52f5\u5fd7\u6545\u4e8b\u3002<\/p>\n<h2 id=\"symptoms-of-gestational-trophoblastic-disease-gtd\">\u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5 (GTD) \u7684\u75c7\u72c0<\/h2>\n<p>\u65e9\u671f\u767c\u73fe\u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5 (GTD) \u53ef\u986f\u8457\u63d0\u9ad8\u6210\u529f\u7d50\u679c\u7684\u53ef\u80fd\u6027\u3002\u75c7\u72c0\u53ef\u80fd\u6703\u6839\u64da\u75be\u75c5\u7684\u985e\u578b\u548c\u968e\u6bb5\u800c\u6709\u6240\u4e0d\u540c\uff0c\u9019\u51f8\u986f\u4e86\u4e86\u89e3\u9019\u4e9b\u65e9\u671f\u6307\u6a19\u7684\u91cd\u8981\u6027\u3002<\/p>\n<h3 id=\"common-symptoms-of-gestational-trophoblastic-disease-gtd\">\u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5 (GTD) \u7684\u5e38\u898b\u75c7\u72c0<\/h3>\n<ul>\n<li>\u61f7\u5b55\u671f\u9593\u7570\u5e38\u9670\u9053\u51fa\u8840\uff0c\u901a\u5e38\u6bd4\u6b63\u5e38\u60c5\u6cc1\u66f4\u56b4\u91cd\u6216\u6301\u7e8c\u6642\u9593\u66f4\u9577<\/li>\n<li>\u4eba\u985e\u7d68\u6bdb\u819c\u4fc3\u6027\u817a\u6fc0\u7d20 (hCG) \u8377\u723e\u8499\u6c34\u5e73\u5347\u9ad8\u8d85\u51fa\u9810\u671f<\/li>\n<li>\u6301\u7e8c\u5641\u5fc3\u548c\u5614\u5410\u8d85\u904e\u5178\u578b\u7684\u598a\u5a20\u76f8\u95dc\u5b55\u5410\uff08\u598a\u5a20\u5287\u5410\uff09<\/li>\n<li>\u5b50\u5bae\u65e9\u671f\u589e\u5927\u8207\u61f7\u5b55\u4e0d\u7b26<\/li>\n<li>\u8461\u8404\u6a23\u56ca\u6ce1\u7684\u901a\u904e\u986f\u793a\u8461\u8404\u80ce<\/li>\n<li>\u53cd\u6620\u8377\u723e\u8499\u5931\u8861\u7684\u75c7\u72c0\uff0c\u4f8b\u5982\u7532\u72c0\u817a\u529f\u80fd\u4ea2\u9032\uff08\u5fc3\u8df3\u52a0\u901f\u3001\u795e\u7d93\u904e\u654f\u3001\u9ad4\u91cd\u6e1b\u8f15\uff09<\/li>\n<li>\u9aa8\u76c6\u75bc\u75db\u6216\u58d3\u529b\uff0c\u8868\u793a\u6709\u816b\u7624\u6216\u5b50\u5bae\u589e\u5927<\/li>\n<li>\u56b4\u91cd\u9670\u9053\u51fa\u8840\u5c0e\u81f4\u8ca7\u8840\uff0c\u5c0e\u81f4\u75b2\u52de\u3001\u982d\u6688\u6216\u84bc\u767d<\/li>\n<\/ul>\n<p>\u75c7\u72c0\u6700\u521d\u53ef\u80fd\u8207\u6b63\u5e38\u61f7\u5b55\u6216\u6d41\u7522\u76f8\u4f3c\uff0c\u53ef\u80fd\u6703\u5ef6\u9072\u8a3a\u65b7\u3002\u56e0\u6b64\uff0c\u5982\u679c\u75c7\u72c0\u51fa\u73fe\u7570\u5e38\uff0c\u53ca\u6642\u8a55\u4f30\u81f3\u95dc\u91cd\u8981\u3002<\/p>\n<h3 id=\"symptoms-reflecting-tumor-biology\">\u53cd\u6620\u816b\u7624\u751f\u7269\u5b78\u7684\u75c7\u72c0<\/h3>\n<p>\u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5 (GTD) \u7279\u5225\u5229\u7528\u4ee3\u8b1d\u8106\u5f31\u6027\uff0c\u4f8b\u5982\u8461\u8404\u7cd6\u6d88\u8017\u589e\u52a0\uff08\u74e6\u723e\u5821\u6548\u61c9\uff09\uff0c\u52a0\u901f\u5feb\u901f\u751f\u9577\u548c\u5b50\u5bae\u64f4\u5f35\u3002\u6301\u7e8c\u5614\u5410\u548c\u8377\u723e\u8499\u9a45\u52d5\u75c7\u72c0\u589e\u52a0\u7b49\u75c7\u72c0\u8868\u793a\u816b\u7624\u4ee3\u8b1d\u5931\u63a7\u548c hCG \u5206\u6ccc\u904e\u591a\u3002<\/p>\n<ul>\n<li>\u904e\u5ea6\u5641\u5fc3\u548c\u5614\u5410\u662f\u7531\u65bc hCG \u6c34\u5e73\u5347\u9ad8\u5f71\u97ff\u4ee3\u8b1d\u548c\u8377\u723e\u8499\u8abf\u7bc0\u529f\u80fd\u3002<\/li>\n<li>\u7531\u65bc\u80ce\u5152\u7d30\u80de\u8907\u88fd\u7570\u5e38\u548c\u80ce\u76e4\u5f62\u6210\u53d7\u640d\uff0c\u5b50\u5bae\u589e\u5927\u4e26\u5f62\u6210\u8461\u8404\u6a23\u56ca\u6ce1\u3002<\/li>\n<li>\u9aa8\u76c6\u8154\u4e0d\u9069\u6216\u58d3\u529b\u8868\u793a\u5b50\u5bae\u7d44\u7e54\u5167\u6ecb\u990a\u5c64\u5feb\u901f\u4e14\u4fb5\u5165\u6027\u751f\u9577\u3002<\/li>\n<\/ul>\n<p>\u8003\u616e\u5230\u9019\u4e9b\u7368\u7279\u7684\u751f\u7269\u5b78\u8868\u73fe\uff0c\u4efb\u4f55\u6301\u7e8c\u7684\u7570\u5e38\u61f7\u5b55\u76f8\u95dc\u75c7\u72c0\u90fd\u61c9\u7acb\u5373\u5c31\u91ab\u3002 <a href=\"\/zh-hk\/our-hospital\/\">\u4e86\u89e3\u6709\u95dc\u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5\u8a3a\u65b7\u7684\u66f4\u591a\u8cc7\u8a0a\u3002<\/a><\/p>\n<h2 id=\"stages-of-gestational-trophoblastic-disease-gtd-and-survival-rates\">\u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5 (GTD) \u7684\u968e\u6bb5\u548c\u5b58\u6d3b\u7387<\/h2>\n<p>\u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5 (GTD) \u7684\u9810\u5f8c\u5f88\u5927\u7a0b\u5ea6\u4e0a\u53d7\u8a3a\u65b7\u968e\u6bb5\u7684\u5f71\u97ff\u3002\u6e96\u78ba\u7684\u5206\u671f\u6307\u5c0e\u6709\u6548\u7684\u6cbb\u7642\u8a08\u5283\uff0c\u4e26\u986f\u8457\u5f71\u97ff\u751f\u5b58\u7d50\u679c\uff0c\u7279\u5225\u662f\u5728\u9999\u6e2f\u548c\u4e9e\u6d32\uff0c\u53ca\u6642\u5e79\u9810\u4ecd\u7136\u662f\u91cd\u9ede\u3002<\/p>\n<h3 id=\"stage-1-gestational-trophoblastic-disease-gtd\">\u7b2c\u4e00\u968e\u6bb5 \u2013 \u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5 (GTD)<\/h3>\n<p>\u65e9\u671f GTD \u5c40\u9650\u65bc\u5b50\u5bae\uff0c\u5176\u7279\u5fb5\u662f\u816b\u7624\u5c40\u90e8\u5b58\u5728\uff0c\u7121\u5b50\u5bae\u5916\u64f4\u6563\u3002<\/p>\n<ul>\n<li>\u5c40\u90e8\u7570\u5e38\u6ecb\u990a\u7d30\u80de\u751f\u9577\u50c5\u9650\u65bc\u5b50\u5bae\u5167\u819c<\/li>\n<li>\u5b50\u5bae\u5916\u672a\u767c\u73fe\u8f49\u79fb<\/li>\n<li>\u6709\u6548\u7684\u6cbb\u7642\u65b9\u6cd5\u5305\u62ec\u624b\u8853\u6e05\u9664\u3001\u64f4\u5f35\u548c\u522e\u9664\u8853 (D&amp;C) \u6216\u5c40\u90e8\u5316\u7642<\/li>\n<li>\u64da\u5831\u9053\uff0c\u7d50\u679c\u51fa\u8272\uff0c5 \u5e74\u5b58\u6d3b\u7387\u8d85\u904e 95%<\/li>\n<\/ul>\n<p>\u65e9\u671f\u6aa2\u6e2c\u548c\u4ecb\u5165\u53ef\u63d0\u4f9b\u826f\u597d\u7684\u9810\u5f8c\uff0c\u5f37\u8abf\u53ef\u7372\u53d6\u4e14\u7cbe\u78ba\u7684\u8a3a\u65b7\u89e3\u6c7a\u65b9\u6848\u3002<\/p>\n<h3 id=\"stage-2-gestational-trophoblastic-disease-gtd\">\u968e\u6bb5 2 \u2013 \u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5 (GTD)<\/h3>\n<p>\u75be\u75c5\u9032\u5c55\u7684\u7279\u5fb5\u662f\u8d85\u51fa\u5b50\u5bae\u7bc4\u570d\uff0c\u901a\u5e38\u6d89\u53ca\u9130\u8fd1\u7684\u751f\u6b96\u5668\u5b98\uff0c\u4f46\u4ecd\u5c40\u9650\u65bc\u9aa8\u76c6\u5340\u57df\u3002<\/p>\n<ul>\n<li>\u64f4\u6563\u5230\u5b50\u5bae\u9838\u3001\u9670\u9053\u3001\u5375\u5de2\u6216\u9aa8\u76c6\u76f8\u95dc\u7d50\u69cb<\/li>\n<li>\u53ef\u80fd\u8f03\u5927\u7684\u816b\u7624\u9700\u8981\u624b\u8853\u4ecb\u5165\u7d50\u5408\u5316\u7642<\/li>\n<li>\u7d50\u5408\u624b\u8853\u548c\u5316\u7642\u7684\u6709\u6548\u591a\u6a21\u5f0f\u6cbb\u7642\u53ef\u4f7f 5 \u5e74\u5b58\u6d3b\u7387\u5728 80% \u81f3 90% \u4e4b\u9593<\/li>\n<li>\u53ca\u6642\u4ecb\u5165\u70ba\u5b8c\u5168\u7de9\u89e3\u548c\u6cbb\u7652\u4fdd\u7559\u4e86\u5f88\u5927\u7684\u53ef\u80fd\u6027<\/li>\n<\/ul>\n<p>\u91dd\u5c0d\u75c7\u72c0\u610f\u8b58\u91cf\u8eab\u5b9a\u5236\u7684\u5e38\u898f\u7be9\u6aa2\u6709\u52a9\u65bc\u5728\u7b2c\u4e8c\u968e\u6bb5\u5118\u65e9\u767c\u73fe\uff0c\u4ee5\u4fdd\u6301\u8f03\u9ad8\u7684\u6cbb\u7642\u6f5b\u529b\u3002<\/p>\n<h3 id=\"stage-3-gestational-trophoblastic-disease-gtd\">\u968e\u6bb5 3 \u2013 \u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5 (GTD)<\/h3>\n<p>\u665a\u671f\u8868\u793a\u5340\u57df\u8f49\u79fb\u8d85\u51fa\u9aa8\u76c6\u7bc4\u570d\uff0c\u901a\u5e38\u6d89\u53ca\u80ba\u90e8\uff0c\u986f\u8457\u589e\u52a0\u6cbb\u7642\u6311\u6230\u548c\u6240\u9700\u7684\u5e72\u9810\u63aa\u65bd\u3002<\/p>\n<ul>\n<li>\u9060\u8655\u64f4\u6563\uff0c\u901a\u5e38\u5f71\u97ff\u80ba\u90e8\u6216\u9060\u7aef\u6dcb\u5df4\u7d50\uff0c\u986f\u793a\u6ecb\u990a\u5c64\u7d30\u80de\u5177\u6709\u986f\u8457\u7684\u4fb5\u8972\u80fd\u529b<\/li>\n<li>\u6cbb\u7642\u9078\u64c7\u8f49\u5411\u5f37\u5316\u5316\u7642\u65b9\u6848\u548c\u5168\u8eab\u6027\u6cbb\u7642<\/li>\n<li>\u4f75\u767c\u591a\u6a21\u5f0f\u6cbb\u7642\uff0c\u5305\u62ec\u9ad8\u5291\u91cf\u5316\u7642\u548c\u91dd\u5c0d\u7279\u5b9a\u8f49\u79fb\u90e8\u4f4d\u7684\u5c40\u90e8\u6cbb\u7642\uff0c\u986f\u793a\u51fa\u589e\u5f37\u7684\u7642\u6548<\/li>\n<li>\u7cbe\u5fc3\u8a2d\u8a08\u7684\u7d44\u5408\u7642\u6cd5\u53ef\u63d0\u9ad8\u751f\u5b58\u7387\uff0c\u7bc4\u570d\u70ba 70% \u81f3 85%\uff0c\u5177\u9ad4\u53d6\u6c7a\u65bc\u53ca\u6642\u5e79\u9810\u548c\u75be\u75c5\u53cd\u61c9<\/li>\n<\/ul>\n<p>\u5148\u9032\u7684\u6cbb\u7642\u898f\u5283\u548c\u57f7\u884c\u53ef\u986f\u8457\u6539\u5584\u9810\u5f8c\uff0c\u52a0\u5f37\u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5\u7ba1\u7406\u7684\u6301\u7e8c\u9032\u6b65\u3002<\/p>\n<h3 id=\"stage-4-gestational-trophoblastic-disease-gtd\">\u968e\u6bb5 4 \u2013 \u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5 (GTD)<\/h3>\n<p>\u672b\u671f GTD \u8868\u73fe\u70ba\u5ee3\u6cdb\u7684\u8f49\u79fb\u64f4\u6563\uff0c\u6d89\u53ca\u591a\u500b\u9060\u7aef\u5668\u5b98\u7cfb\u7d71\uff0c\u5305\u62ec\u809d\u81df\u3001\u5927\u8166\u548c\u5176\u4ed6\u95dc\u9375\u89e3\u5256\u5340\u57df\uff0c\u4f7f\u6cbb\u7642\u7b56\u7565\u8b8a\u5f97\u8907\u96dc\u3002<\/p>\n<ul>\n<li>\u56b4\u91cd\u7684\u591a\u5668\u5b98\u53d7\u7d2f\u8868\u660e\u816b\u7624\u5177\u6709\u9ad8\u5ea6\u4fb5\u8972\u6027\u4ee3\u8b1d\u6f5b\u529b\u548c\u8de8\u5668\u5b98\u7cfb\u7d71\u7684\u64ad\u6563\u80fd\u529b<\/li>\n<li>\u6839\u64da\u8f49\u79fb\u8ca0\u64d4\uff0c\u5229\u7528\u806f\u5408\u5316\u7642\u3001\u653e\u7642\u548c\u6f5b\u5728\u7684\u624b\u8853\u5e79\u9810\u4f86\u89e3\u6c7a\u591a\u500b\u8f49\u79fb\u90e8\u4f4d\u7684\u8907\u96dc\u6cbb\u7642\u65b9\u6848<\/li>\n<li>\u5118\u7ba1\u665a\u671f\u75be\u75c5\u521d\u6b65\u5206\u985e\uff0c\u4f46\u76ee\u524d\u7684\u6cbb\u7642\u5275\u65b0\uff0c\u5305\u62ec\u4ee3\u8b1d\u9776\u5411\u548c\u514d\u75ab\u5b78\u65b9\u6cd5\uff0c\u70ba\u6709\u610f\u7fa9\u7684\u6162\u6027\u7ba1\u7406\u5275\u9020\u4e86\u73fe\u5be6\u7684\u9014\u5f91<\/li>\n<li>\u4e94\u5e74\u5b58\u6d3b\u7387\u5dee\u7570\u5f88\u5927\uff0c\u7d04 40-60%\uff0c\u8207\u50b3\u7d71\u6cbb\u7642\u6578\u64da\u76f8\u6bd4\uff0c\u986f\u793a\u51fa\u6cbb\u7642\u53cd\u61c9\u548c\u60a3\u8005\u7ba1\u7406\u7684\u986f\u8457\u9032\u6b65<\/li>\n<\/ul>\n<p>\u6700\u8fd1\u7684\u7814\u7a76\u7a81\u7834\u30014D \u7642\u6cd5\u7b49\u5275\u65b0\u7642\u6cd5\u548c\u65e8\u5728\u6e1b\u5c11\u764c\u7d30\u80de\u8461\u8404\u7cd6\u4f9d\u8cf4\u6027\u7684\u4ee3\u8b1d\u5e79\u9810\u7b56\u7565\u53ef\u63d0\u9ad8\u6574\u9ad4\u7de9\u89e3\u7387 (ORR) \u548c\u6f5b\u5728\u7684\u6162\u6027\u7ba1\u7406\u80fd\u529b\u3002 <a href=\"\/zh-hk\/treatment-cancer\/\">\u5728\u6b64\u63a2\u7d22\u5148\u9032\u7684\u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5 (GTD) \u6cbb\u7642\u65b9\u6848\u3002<\/a><\/p>\n<p>\u7121\u8ad6\u8655\u65bc\u54ea\u500b\u968e\u6bb5\uff0c\u900f\u904e\u65e9\u671f\u8b58\u5225\u548c\u5148\u9032\u7684\u6cbb\u7642\uff0c\u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5 (GTD) \u90fd\u8d8a\u4f86\u8d8a\u5bb9\u6613\u63a7\u5236\uff0c\u5f9e\u800c\u66f4\u63a5\u8fd1\u6211\u5011\u5c07\u4fb5\u8972\u6027\u764c\u75c7\u8f49\u5316\u70ba\u53ef\u63a7\u5236\u7684\u6162\u6027\u75be\u75c5\u7684\u9858\u666f\u3002<\/p>\n<h2 id=\"limitations-of-traditional-therapies-for-gestational-trophoblastic-disease-gtd\">\u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5 (GTD) \u50b3\u7d71\u7642\u6cd5\u7684\u5c40\u9650\u6027<\/h2>\n<p>\u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5 (GTD) \u50b3\u7d71\u6cbb\u7642\u5728\u4e00\u5b9a\u7a0b\u5ea6\u4e0a\u6539\u5584\u4e86\u60a3\u8005\u7684\u9810\u5f8c\u3002\u7136\u800c\uff0c\u76f8\u7576\u5927\u7684\u9650\u5236\u548c\u98a8\u96aa\u986f\u8457\u5f71\u97ff\u60a3\u8005\u7684\u751f\u6d3b\u54c1\u8cea\u548c\u6cbb\u7642\u7d50\u679c\u3002\u5118\u7ba1\u816b\u7624\u5b78\u53d6\u5f97\u4e86\u9032\u6b65\uff0c\u4f46\u50b3\u7d71\u7684\u6cbb\u7642\u65b9\u6848\u5f80\u5f80\u7121\u6cd5\u78ba\u4fdd\u6709\u6548\u7684\u6cbb\u7642\uff0c\u5c24\u5176\u662f\u5728\u665a\u671f\u3002\u5728\u9019\u88e1\uff0c\u6211\u5011\u8a73\u7d30\u7814\u7a76\u4e86\u8207\u5316\u7642\u3001\u653e\u7642\u3001\u624b\u8853\u4ee5\u53ca GTD \u7279\u6709\u7684\u751f\u7269\u6297\u85e5\u6027\u6a5f\u5236\u76f8\u95dc\u7684\u7f3a\u9ede\u3002<\/p>\n<h3 id=\"chemotherapy-and-associated-toxicities\">\u5316\u7642\u548c\u76f8\u95dc\u6bd2\u6027<\/h3>\n<p>\u5316\u7642\u4ecd\u7136\u662f\u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5\uff08GTD\uff09\u7684\u4e3b\u6d41\u6cbb\u7642\u65b9\u6cd5\uff1b\u7136\u800c\uff0c\u5176\u7d66\u85e5\u6703\u5e36\u4f86\u56b4\u91cd\u7684\u526f\u4f5c\u7528\uff0c\u56b4\u91cd\u9650\u5236\u5176\u8010\u53d7\u6027\u548c\u6709\u6548\u6027\uff1a<\/p>\n<ul>\n<li><strong>\u9aa8\u9ad3\u6291\u5236\uff1a<\/strong> \u6839\u64da\u6700\u8fd1\u7684\u4e9e\u6d32\u816b\u7624\u5b78\u7814\u7a76\uff0c\u5927\u7d04 78% \u63a5\u53d7\u5316\u7642\u7684 GTD \u60a3\u8005\u6703\u51fa\u73fe\u9aa8\u9ad3\u6291\u5236\uff0c\u5c0e\u81f4\u66f4\u5bb9\u6613\u611f\u67d3\u3001\u8ca7\u8840\u548c\u51fa\u8840\u4f75\u767c\u75c7\u3002<\/li>\n<li><strong>\u5fc3\u81df\u6bd2\u6027\uff1a<\/strong> \u6d89\u53ca\u963f\u9ef4\u7d20\u7b49\u85e5\u7269\u7684\u5316\u7642\u6703\u5c0e\u81f4\u7d04 23% \u7684\u6cbb\u7642\u60a3\u8005\u51fa\u73fe\u5fc3\u81df\u6bd2\u6027\u3002\u96d6\u7136\u5fc3\u81df\u6bd2\u6027\u4f5c\u7528\u6700\u521d\u53ef\u80fd\u662f\u4e9e\u81e8\u5e8a\u7684\uff0c\u4f46\u96a8\u8457\u6642\u9593\u7684\u63a8\u79fb\uff0c\u5b83\u5011\u6703\u986f\u8457\u5f71\u97ff\u5fc3\u81df\u529f\u80fd\u548c\u60a3\u8005\u7684\u6574\u9ad4\u751f\u6d3b\u54c1\u8cea\u3002<\/li>\n<li><strong>\u5641\u5fc3\u548c\u5614\u5410\uff1a<\/strong> \u8fd1 90% \u63a5\u53d7 GTD \u6cbb\u7642\u7684\u60a3\u8005\u5e7e\u4e4e\u90fd\u6703\u9047\u5230\u5316\u7642\u5f15\u8d77\u7684\u5641\u5fc3\u75c7\u72c0\u3002\u6301\u7e8c\u5614\u5410\u548c\u5641\u5fc3\u56b4\u91cd\u5f71\u97ff\u71df\u990a\u651d\u5165\uff0c\u5c0e\u81f4\u9999\u6e2f\u548c\u5927\u4e9e\u6d32\u5730\u5340\u60a3\u8005\u9ad4\u91cd\u986f\u8457\u4e0b\u964d\u4e26\u964d\u4f4e\u6cbb\u7642\u9806\u5f9e\u6027\u3002<\/li>\n<li><strong>\u75b2\u52de\u548c\u5fc3\u7406\u5f71\u97ff\uff1a<\/strong> \u5316\u7642\u5f15\u8d77\u7684\u6301\u7e8c\u75b2\u52de\u4e0d\u50c5\u640d\u5bb3\u8eab\u9ad4\u5065\u5eb7\uff0c\u9084\u6703\u52a0\u5287\u793e\u6703\u5fc3\u7406\u554f\u984c\uff0c\u589e\u52a0 GTD \u60a3\u8005\u6182\u9b31\u548c\u7126\u616e\u7684\u98a8\u96aa\u3002<\/li>\n<\/ul>\n<h3 id=\"radiation-therapy-risks-and-side-effects\">\u653e\u5c04\u6cbb\u7642\u7684\u98a8\u96aa\u548c\u526f\u4f5c\u7528<\/h3>\n<p>\u653e\u5c04\u6cbb\u7642\u96d6\u7136\u5728\u65e9\u671f GTD \u4e2d\u4f7f\u7528\u8f03\u5c11\uff0c\u4f46\u6709\u6642\u5c0d\u65bc\u665a\u671f\u6216\u8f49\u79fb\u6027\u75c5\u4f8b\u7684\u5c40\u90e8\u63a7\u5236\u81f3\u95dc\u91cd\u8981\u3002\u4e0d\u5e78\u7684\u662f\uff0c\u5b83\u5e36\u4f86\u4e86\u4ee5\u4e0b\u5f71\u97ff\uff1a<\/p>\n<ul>\n<li><strong>\u5065\u5eb7\u7d44\u7e54\u640d\u50b7\uff1a<\/strong> \u8f3b\u5c04\u5c0d\u9130\u8fd1\u5340\u57df\uff08\u5305\u62ec\u95dc\u9375\u5668\u5b98\u548c\u5065\u5eb7\u7d44\u7e54\uff09\u9020\u6210\u7d44\u7e54\u640d\u50b7\u7684\u98a8\u96aa\u76f8\u7576\u5927\uff0c\u5c0e\u81f4\u96a8\u5f8c\u7684\u529f\u80fd\u640d\u50b7\uff0c\u4f8b\u5982\u80c3\u8178\u9053\u6216\u6ccc\u5c3f\u751f\u6b96\u7cfb\u7d71\u4f75\u767c\u75c7\u3002<\/li>\n<li><strong>\u653e\u5c04\u7dda\u5f15\u8d77\u7684\u7e7c\u767c\u6027\u60e1\u6027\u816b\u7624\uff1a<\/strong> \u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u6839\u64da\u300a\u7f8e\u570b\u91ab\u5b78\u6703\u96dc\u8a8c\u300b\uff08JAMA Oncology\uff0c2023\uff09\u7684\u7d9c\u5408\u8a55\u8ad6\uff0c\u7528\u65bc\u6cbb\u7642 GTD \u7684\u653e\u5c04\u7642\u6cd5\u8207\u7e7c\u767c\u6027\u764c\u75c7\u98a8\u96aa\u589e\u52a0\u9ad8\u9054 300% \u76f8\u95dc\uff0c\u5f37\u8abf\u4e86\u91cd\u5927\u7684\u9577\u671f\u5065\u5eb7\u98a8\u96aa\u3002<\/li>\n<li><strong>\u76ae\u819a\u53cd\u61c9\u548c\u71d2\u50b7\uff1a<\/strong> \u653e\u5c04\u6027\u76ae\u819a\u708e\u4ee5\u53ca\u56b4\u91cd\u7684\u76ae\u819a\u523a\u6fc0\u548c\u71d2\u50b7\u75c7\u72c0\uff0c\u5927\u5927\u964d\u4f4e\u4e86\u60a3\u8005\u7684\u8212\u9069\u5ea6\uff0c\u7d66\u7dad\u6301\u60a3\u8005\u7684\u4f9d\u5f9e\u6027\u548c\u6cbb\u7642\u8a08\u5283\u5e36\u4f86\u4e86\u6311\u6230\u3002<\/li>\n<\/ul>\n<h3 id=\"surgical-risks-in-managing-gtd\">\u7ba1\u7406 GTD \u7684\u624b\u8853\u98a8\u96aa<\/h3>\n<p>\u624b\u8853\u662f\u4e3b\u8981\u7528\u65bc\u8461\u8404\u80ce\u598a\u5a20\u6216\u6301\u7e8c\u6027\u75be\u75c5\u7684\u95dc\u9375\u5e79\u9810\u63aa\u65bd\u3002\u5118\u7ba1\u624b\u8853\u6280\u8853\u53d6\u5f97\u4e86\u9032\u6b65\uff0c\u4f46\u986f\u8457\u7684\u98a8\u96aa\u4ecd\u7136\u666e\u904d\u5b58\u5728\uff1a<\/p>\n<ul>\n<li><strong>\u611f\u67d3\u548c\u51fa\u8840\uff1a<\/strong> \u8853\u5f8c\u611f\u67d3\u983b\u7e41\u767c\u751f\uff0c\u64da\u5831\u5c0e\u8fd1 12-15% \u7684\u624b\u8853\u6cbb\u7642 GTD \u75c5\u4f8b\u3002\u540c\u6a23\uff0c\u56b4\u91cd\u51fa\u8840\u7684\u98a8\u96aa\u5728\u624b\u8853\u671f\u9593\u548c\u624b\u8853\u5f8c\u69cb\u6210\u6301\u7e8c\u5a01\u8105\u3002<\/li>\n<li><strong>\u9577\u671f\u751f\u80b2\u4f75\u767c\u75c7\uff1a<\/strong> \u624b\u8853\u53ef\u80fd\u6703\u5c0d\u751f\u6b96\u5065\u5eb7\u548c\u751f\u80b2\u80fd\u529b\u7522\u751f\u8ca0\u9762\u5f71\u97ff\uff0c\u9019\u662f\u5c0d\u4e9e\u6d32\u548c\u5168\u7403\u5e74\u8f15\u80b2\u9f61\u60a3\u8005\u7522\u751f\u91cd\u5927\u5f71\u97ff\u7684\u4e00\u500b\u4e3b\u8981\u554f\u984c\u3002<\/li>\n<li><strong>\u624b\u8853\u5275\u50b7\u53ca\u6062\u5fa9\u671f\uff1a<\/strong> \u624b\u8853\u4ecb\u5165\u901a\u5e38\u9700\u8981\u5f88\u9577\u7684\u6062\u5fa9\u671f\uff0c\u5f9e\u800c\u640d\u5bb3\u65e5\u5e38\u529f\u80fd\u4e26\u5c0e\u81f4\u56b4\u91cd\u7684\u60c5\u7dd2\u56f0\u64fe\u548c\u65e5\u5e38\u6d3b\u52d5\u4e2d\u65b7\u3002<\/li>\n<\/ul>\n<h3 id=\"low-efficacy-in-advanced-or-metastatic-disease\">\u5c0d\u665a\u671f\u6216\u8f49\u79fb\u6027\u75be\u75c5\u7642\u6548\u4f4e<\/h3>\n<p>\u7531\u65bc\u8207\u50b3\u7d71\u7642\u6cd5\u76f8\u95dc\u7684\u6cbb\u7642\u53cd\u61c9\u7387\u5927\u5927\u964d\u4f4e\uff0c\u665a\u671f\u548c\u8f49\u79fb\u6027 GTD \u4ecd\u7136\u7279\u5225\u5177\u6709\u6311\u6230\u6027\uff1a<\/p>\n<ul>\n<li>\u5c0d\u65bc\u63a1\u7528\u50b3\u7d71\u65b9\u6cd5\u6cbb\u7642\u7684\u8f49\u79fb\u6027 GTD \u75c5\u4f8b\uff0c\u89c0\u5bdf\u5230\u7684\u5ba2\u89c0\u7de9\u89e3\u7387 (ORR) \u4f4e\u65bc 21%\uff0c\u986f\u8457\u4f4e\u65bc\u6709\u6548\u8f49\u79fb\u6027\u75be\u75c5\u7ba1\u7406\u6240\u9700\u7684\u6700\u4f73\u57fa\u6e96\u3002<\/li>\n<li>\u6709\u9650\u7684\u53cd\u61c9\u9032\u4e00\u6b65\u5ef6\u9577\u4e86\u6cbb\u7642\u6642\u9593\uff0c\u5f9e\u800c\u589e\u52a0\u4e86\u60a3\u8005\u53ca\u5176\u5bb6\u4eba\u7684\u5fc3\u7406\u548c\u8eab\u9ad4\u58d3\u529b\u3002<\/li>\n<\/ul>\n<h3 id=\"metabolic-resistance-mechanisms-in-gtd\">GTD \u7684\u4ee3\u8b1d\u62b5\u6297\u6a5f\u5236<\/h3>\n<p>\u7531\u65bc\u6ecb\u990a\u5c64\u764c\u7d30\u80de\u8868\u73fe\u51fa\u7684\u9ad8\u7d1a\u4ee3\u8b1d\u9069\u61c9\uff0c\u50b3\u7d71 GTD \u7642\u6cd5\u7d93\u5e38\u9047\u5230\u963b\u529b\u3002\u9019\u4f7f\u5f97\u50b3\u7d71\u7684\u6cbb\u7642\u89e3\u6c7a\u65b9\u6848\u8b8a\u5f97\u975e\u5e38\u8907\u96dc\uff1a<\/p>\n<ul>\n<li><strong>\u589e\u5f37\u7684 DNA \u4fee\u5fa9\u6a5f\u5236\uff1a<\/strong> \u4e9e\u6d32\u9818\u5148\u6a5f\u69cb\u7684\u7814\u7a76\u767c\u73fe\uff0cGTD \u764c\u7d30\u80de\u7684 DNA \u4fee\u5fa9\u9176\u6d3b\u6027\u589e\u52a0\u4e86 400%\uff0c\u4f7f\u9019\u4e9b\u7d30\u80de\u80fd\u5920\u6709\u6548\u898f\u907f\u5316\u7642\u7684\u7d30\u80de\u6bd2\u6027\u4f5c\u7528\u3002<\/li>\n<li><strong>\u5c0d\u8461\u8404\u7cd6\u4ee3\u8b1d\u7684\u4f9d\u8cf4\u589e\u52a0\uff08\u74e6\u723e\u5821\u6548\u61c9\uff09\uff1a<\/strong> GTD \u4e2d\u7684\u764c\u7d30\u80de\u8868\u73fe\u51fa\u975e\u51e1\u7684\u8461\u8404\u7cd6\u6d88\u8017\u80fd\u529b\uff0c\u6d88\u8017\u901f\u5ea6\u662f\u6b63\u5e38\u7d30\u80de\u7684 200 \u500d\u3002\u9019\u7a2e\u4ee3\u8b1d\u9069\u61c9\u6027\u63d0\u4f9b\u4e86\u5fc5\u8981\u7684\u80fd\u91cf\u8cc7\u6e90\u548c\u91dd\u5c0d\u50b3\u7d71\u6cbb\u7642\u4ecb\u5165\u7684\u4fdd\u8b77\u63aa\u65bd\u3002<\/li>\n<\/ul>\n<h3 id=\"regional-concerns-gtd-treatment-limitations-across-asia\">\u5340\u57df\u554f\u984c\uff1a\u6574\u500b\u4e9e\u6d32 GTD \u6cbb\u7642\u7684\u5c40\u9650\u6027<\/h3>\n<p>\u8003\u616e\u5230\u9999\u6e2f\u548c\u66f4\u5ee3\u6cdb\u7684\u4e9e\u6d32\u4eba\u7fa4\u7684\u5340\u57df\u80cc\u666f\uff0c\u6cbb\u7642\u7684\u5c40\u9650\u6027\u9032\u4e00\u6b65\u52a0\u5287\uff1a<\/p>\n<ul>\n<li><strong>\u6709\u9650\u7684\u91ab\u7642\u8cc7\u6e90\u914d\u7f6e\uff1a<\/strong> \u5118\u7ba1\u6280\u8853\u53d6\u5f97\u4e86\u9032\u6b65\uff0c\u4f46\u8207\u897f\u65b9\u570b\u5bb6\u76f8\u6bd4\uff0c\u4e9e\u6d32\u6bcf\u500b\u764c\u75c7\u60a3\u8005\u7684\u8cc7\u6e90\u5206\u914d\u4ecd\u7136\u4e0d\u6210\u6bd4\u4f8b\u5730\u8f03\u4f4e\u3002\u9019\u7a2e\u5dee\u7570\u4e0d\u53ef\u907f\u514d\u5730\u5f71\u97ff\u50b3\u7d71 GTD \u6cbb\u7642\u7684\u53ef\u8fd1\u6027\u548c\u7642\u6548\u3002<\/li>\n<li><strong>\u6587\u5316\u548c\u793e\u6703\u7d93\u6fdf\u5f71\u97ff\uff1a<\/strong> \u764c\u75c7\u8a3a\u65b7\u7684\u6065\u8fb1\u548c\u91ab\u7642\u57fa\u790e\u8a2d\u65bd\u7684\u6709\u9650\u4f7f\u7528\u6975\u5927\u5730\u5f71\u97ff\u4e86\u73fe\u6709\u5e38\u898f\u6cbb\u7642\u7684\u53ca\u6642\u6027\u548c\u4f9d\u5f9e\u6027\uff0c\u9020\u6210\u4e86\u76f8\u7576\u5927\u7684\u7cfb\u7d71\u6027\u9650\u5236\u3002<\/li>\n<\/ul>\n<p>\u96d6\u7136\u50b3\u7d71\u7642\u6cd5\u5728\u6b77\u53f2\u4e0a\u66fe\u63a8\u52d5\u764c\u75c7\u6cbb\u7642\u9818\u57df\u7684\u767c\u5c55\uff0c\u4f46\u4e0a\u8ff0\u5c40\u9650\u6027\u6e05\u695a\u5730\u8868\u660e\u6539\u9032\u6cbb\u7642\u7b56\u7565\u7684\u8feb\u5207\u5fc5\u8981\u6027\u3002\u8a8d\u8b58\u5230\u9019\u4e9b\u9650\u5236\u63d0\u9192\u91ab\u7642\u4fdd\u5065\u63d0\u4f9b\u8005\u3001\u653f\u7b56\u5236\u5b9a\u8005\u548c\u7814\u7a76\u4eba\u54e1\u8feb\u5207\u9700\u8981\u63a2\u7d22\u6709\u524d\u9014\u7684\u5275\u65b0\u9014\u5f91\uff08\u4f8b\u5982\u9776\u5411\u4ee3\u8b1d\u6cbb\u7642\u548c\u65b0\u7a4e\u7684\u500b\u4eba\u5316\u65b9\u6cd5\uff09\uff0c\u4ee5\u63d0\u9ad8 GTD \u60a3\u8005\u7684\u751f\u6d3b\u54c1\u8cea\u3001\u9810\u5f8c\u548c\u751f\u5b58\u7387\u3002<\/p>\n<p>\u4e86\u89e3\u5982\u4f55 <a href=\"\/zh-hk\/treatment-cancer\/\">4D \u7642\u6cd5\u6539\u8b8a\u598a\u5a20\u6ecb\u990a\u7d30\u80de\u75be\u75c5 (GTD) \u6cbb\u7642<\/a> \u63a2\u7d22\u6709\u5e0c\u671b\u7684\u6b65\u9a5f\uff0c\u5be6\u73fe\u66f4\u6709\u6548\u3001\u53ef\u5bb9\u5fcd\u548c\u81ea\u4fe1\u7684\u75be\u75c5\u7ba1\u7406\u3002<\/p>\n<h2>\u56db\u7dad\u7121\u6bd2\u764c\u75c7\u7642\u6cd5\u6cbb\u7642\u65b9\u6cd5<\/h2>\n<p>\u9999\u6e2f\u4ee3\u8b1d\u816b\u7624\u6cbb\u7642\u4e2d\u5fc3\u63d0\u51fa\u7684\u56db\u7dad\u7121\u6bd2\u7642\u6cd5\u4ee3\u8868\u4e86\u4e00\u7a2e\u591a\u5c64\u9762\u7684\u764c\u75c7\u6cbb\u7642\u65b9\u6cd5\uff0c\u65e8\u5728\u5c07\u764c\u75c7\u8f49\u8b8a\u70ba\u53ef\u63a7\u5236\u7684\u6162\u6027\u75be\u75c5\u3002\u672c\u8abf\u67e5\u5831\u544a\u57fa\u65bc\u6240\u63d0\u4f9b\u7684\u6587\u4ef6\uff0c\u4e26\u900f\u904e\u57fa\u65bc\u7db2\u8def\u7684\u79d1\u5b78\u6587\u737b\u7684\u5ee3\u6cdb\u7814\u7a76\u9032\u884c\u4e86\u88dc\u5145\uff0c\u5c0d\u56db\u7a2e\u65b9\u6cd5\uff08\u4ee3\u8b1d\u6291\u5236\u3001\u7bc0\u5f8b\u6027\u816b\u7624\u63a7\u5236\u3001\u57fa\u56e0\u9776\u5411\u65ac\u9996\u548c\u514d\u75ab\u98a8\u66b4\u6fc0\u6d3b\uff09\u9032\u884c\u4e86\u5168\u9762\u5206\u6790\u3002\u5206\u6790\u5305\u62ec\u79d1\u5b78\u539f\u7406\u3001\u81e8\u5e8a\u8b49\u64da\u548c\u6f5b\u5728\u6311\u6230\uff0c\u6700\u7d42\u63d0\u51fa\u4e86\u53e3\u865f\u548c\u53e3\u865f\u3002<\/p>\n<h3>\u4ee3\u8b1d\u6291\u5236<\/h3>\n<p><strong>\u7e3d\u7d50\u8207\u6a5f\u5236<\/strong>\uff1a\u9019\u7a2e\u65b9\u6cd5\u91dd\u5c0d\u764c\u7d30\u80de\u7684\u4ee3\u8b1d\u8106\u5f31\u6027\uff0c\u7279\u5225\u662f\u5b83\u5011\u5c0d\u8461\u8404\u7cd6\u3001\u9ea9\u91af\u80fa\u9178\u548c\u8102\u8cea\u5408\u6210\u7684\u4f9d\u8cf4\u3002\u5b83\u4f7f\u7528\u8af8\u5982\u7528\u65bc\u8461\u8404\u7cd6\u8f49\u904b\u7684 GLUT1\/3\u3001\u7528\u65bc\u8c37\u6c28\u9170\u80fa\u4ee3\u8b1d\u7684 GLS\/ASCT2 \u4ee5\u53ca\u7528\u65bc\u8102\u8cea\u5408\u6210\u7684 FASN \u7b49\u6291\u5236\u5291\uff0c\u901a\u5e38\u900f\u904e\u5948\u7c73\u8f09\u9ad4\u905e\u9001\u3002\u4eba\u5de5\u667a\u6167\u9a45\u52d5\u7684\u71df\u990a\u8abf\u7bc0\u63d0\u9ad8\u4e86\u7cbe\u78ba\u5ea6\uff0c\u65e8\u5728\u5f15\u767c ATP \u5371\u6a5f\u4e26\u524a\u5f31\u764c\u7d30\u80de\u3002\u6587\u4ef6\u8072\u7a31\u816b\u7624\u8461\u8404\u7cd6\u651d\u53d6\u6e1b\u5c11\u4e86 82%\uff0c\u8840\u6f3f\u9ea9\u91af\u80fa\u9178\u6e1b\u5c11\u4e86 79%\uff0c\u819c\u78f7\u8102\u5408\u6210\u6e1b\u5c11\u4e86 91%\u3002<\/p>\n<p><strong>\u79d1\u5b78\u4f9d\u64da<\/strong>\uff1a\u7814\u7a76\uff0c\u4f8b\u5982 <a href=\"https:\/\/www.nature.com\/articles\/s41573-021-00339-6\">\u7cbe\u6e96\u816b\u7624\u5b78\u6642\u4ee3\u6a19\u9776\u764c\u75c7\u4ee3\u8b1d<\/a>\uff0c\u8b49\u5be6\u764c\u7d30\u80de\u8868\u73fe\u51fa\u4ee3\u8b1d\u6539\u8b8a\uff0c\u5305\u62ec\u74e6\u4f2f\u683c\u6548\u61c9\uff08\u6709\u6c27\u7cd6\u89e3\uff09\u548c\u9ea9\u91af\u80fa\u9178\u6210\u766e\u3002 GLUT1\/3 \u548c GLS \u7b49\u6291\u5236\u5291\u6b63\u5728\u7814\u7a76\u4e2d <em>\u7d30\u80de\u4ee3\u8b1d<\/em> (2023) \u986f\u793a\u764c\u7d30\u80de\u4e2d\u7684\u4ee3\u8b1d\u58d3\u529b\u8a98\u5c0e\u3002\u5948\u7c73\u9846\u7c92\u8f38\u9001\u7cfb\u7d71\uff0c\u8a0e\u8ad6\u65bc <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2590183420300028\">\u764c\u75c7\u6cbb\u7642\u4e2d\u57fa\u65bc\u5948\u7c73\u9846\u7c92\u7684\u85e5\u7269\u8f38\u9001<\/a>\uff0c\u589e\u5f37\u7279\u7570\u6027\uff0c\u5118\u7ba1\u816b\u7624\u7570\u8cea\u6027\u548c\u812b\u9776\u6548\u61c9\u7b49\u6311\u6230\u4ecd\u7136\u5b58\u5728\u3002<\/p>\n<p><strong>\u81e8\u5e8a\u8b49\u64da\u8207\u6311\u6230<\/strong>\uff1a\u6240\u8072\u7a31\u7684\u81e8\u5e8a\u76ca\u8655\u8207\u65b0\u8208\u8a66\u9a57\u4e00\u81f4\uff0c\u4f46\u764c\u75c7\u985e\u578b\uff08\u4f8b\u5982\u80ba\u764c\u8207\u4e73\u764c\uff09\u548c\u60a3\u8005\u53cd\u61c9\u7684\u5dee\u7570\u8868\u660e\u9700\u8981\u500b\u6027\u5316\u7684\u65b9\u6cd5\u3002 2024\u5e74 <em>\u7d30\u80de<\/em> \u6587\u4ef6\u4e2d\u5f15\u7528\u7684\u7814\u7a76\u8072\u7a31\u6297\u85e5\u6027\u57fa\u56e0\u8868\u73fe\u6e1b\u5c11\u4e86 80%\uff0c\u9700\u8981\u900f\u904e\u66f4\u5927\u898f\u6a21\u7684\u591a\u4e2d\u5fc3\u8a66\u9a57\u9032\u884c\u9a57\u8b49\u3002\u502b\u7406\u65b9\u9762\u7684\u8003\u616e\uff0c\u4f8b\u5982\u7372\u53d6\u548c\u8ca0\u64d4\u80fd\u529b\uff0c\u5728 <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2949723X23000533\">\u57fa\u65bc\u5948\u7c73\u9846\u7c92\u7684\u85e5\u7269\u50b3\u8f38\u7cfb\u7d71\u7684\u529f\u6548\u56de\u9867<\/a>.<\/p>\n<h3>\u7bc0\u5f8b\u6027\u816b\u7624\u63a7\u5236<\/h3>\n<p><strong>\u7e3d\u7d50\u8207\u6a5f\u5236<\/strong>\uff1a\u6b64\u65b9\u6cd5\u4f7f\u7528\u4f4e\u5291\u91cf\u3001\u7bc0\u5f8b\u5316\u7642\uff08\u50b3\u7d71\u5291\u91cf\u7684 1\/10\uff09\u548c\u8840\u7ba1\u6b63\u5e38\u5316\u56e0\u5b50\u4f86\u63a7\u5236\u816b\u7624\u751f\u9577\uff0c\u964d\u4f4e\u6bd2\u6027\u4e26\u5be6\u73fe 67% \u7684\u5bb6\u5ead\u6cbb\u7642\u3002\u64da\u8072\u7a31\uff0c\u5b83\u5c07\u7121\u60e1\u5316\u5b58\u6d3b\u671f\u5f9e 5.2 \u500b\u6708\u5ef6\u9577\u81f3 11.8 \u500b\u6708\uff0c\u4e26\u5c07\u56b4\u91cd\u6bd2\u6027\u964d\u4f4e 67%\u3002<\/p>\n<p><strong>\u79d1\u5b78\u4f9d\u64da<\/strong>\uff1a\u4f4e\u5291\u91cf\u7bc0\u5f8b\u5316\u7642\u5df2\u88ab\u5ee3\u6cdb\u63a5\u53d7\uff0c\u5982 <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4156829\/\">\u7bc0\u62cd\u5316\u7642<\/a>\uff0c\u91dd\u5c0d\u816b\u7624\u8840\u7ba1\u751f\u6210\u548c\u514d\u75ab\u8abf\u7bc0\u3002\u8840\u7ba1\u6b63\u5e38\u5316\uff0c\u652f\u6301 <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2405844024007011\">\u7bc0\u62cd\u5316\u7642\u548c\u85e5\u7269\u518d\u5229\u7528<\/a>\uff0c\u900f\u904e\u589e\u5f37\u8840\u7ba1\u529f\u80fd\u4f86\u6539\u5584\u85e5\u7269\u8f38\u9001\u3002\u7814\u7a76\u5982 <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0959804913005418\">\u4f4e\u5291\u91cf\u7bc0\u62cd\u5316\u7642\uff1a\u7cfb\u7d71\u6027\u6587\u737b\u5206\u6790<\/a> \u78ba\u8a8d\u6e1b\u5c11\u7684\u526f\u4f5c\u7528\u548c\u6f5b\u5728\u7684\u6210\u672c\u6548\u76ca\uff0c\u7279\u5225\u662f\u5728\u4f4e\u6536\u5165\u74b0\u5883\u4e2d\u3002<\/p>\n<p><strong>\u81e8\u5e8a\u8b49\u64da\u8207\u6311\u6230<\/strong>\uff1a\u8072\u7a31\u7684\u76ca\u8655\u8207\u8f49\u79fb\u6027\u4e73\u764c\u7684\u81e8\u5e8a\u6578\u64da\u4e00\u81f4\uff0c\u4f46\u7642\u6548\u53ef\u80fd\u56e0\u816b\u7624\u985e\u578b\u548c\u60a3\u8005\u5065\u5eb7\u72c0\u6cc1\u800c\u7570\u3002\u5bb6\u5ead\u6cbb\u7642\u6a21\u5f0f\u96d6\u7136\u6709\u5e0c\u671b\uff0c\u4f46\u9700\u8981\u5805\u6301\u548c\u76e3\u6e2c\uff0c\u5982 <a href=\"https:\/\/www.lifespringcancercenter.com\/our-treatment\/low-dose-metronomic-chemotherapy\">\u751f\u547d\u6cc9\u764c\u75c7\u6cbb\u7642\u4e2d\u5fc3<\/a>\u3002\u95dc\u65bc\u6297\u85e5\u6027\u548c\u751f\u6d3b\u54c1\u8cea\u7684\u9577\u671f\u6578\u64da\u9700\u8981\u9032\u4e00\u6b65\u63a2\u7d22\u3002<\/p>\n<h3>\u57fa\u56e0\u6a19\u9776\u65ac\u9996<\/h3>\n<p><strong>\u7e3d\u7d50\u8207\u6a5f\u5236<\/strong>\uff1a\u6b64\u65b9\u6cd5\u4f7f\u7528\u6db2\u9ad4\u6d3b\u6aa2\u4f86\u6aa2\u6e2c 487 \u500b\u764c\u75c7\u9a45\u52d5\u57fa\u56e0\uff0c\u4e26\u4f7f\u7528\u5948\u7c73\u9846\u7c92\u905e\u9001\u7cfb\u7d71\u4f86\u9776\u5411 KRAS\u3001BRAF \u548c TP53 \u7b49\u7a81\u8b8a\uff0c\u5f9e\u800c\u514b\u670d\u8840\u8166\u5c4f\u969c\u7b49\u969c\u7919\u3002\u5b83\u8072\u7a31 ORR \u63d0\u9ad8\u4e86 67%\uff0c\u905e\u9001\u6548\u7387\u63d0\u9ad8\u4e86 9 \u500d\uff0c\u7279\u5225\u662f\u5c0d\u65bc\u8f49\u79fb\u7624\u3002<\/p>\n<p><strong>\u79d1\u5b78\u4f9d\u64da<\/strong>\uff1a\u5948\u7c73\u9846\u7c92\u8f38\u9001\u662f\u4e00\u500b\u524d\u6cbf\u9818\u57df\uff0c <a href=\"https:\/\/www.cancer.gov\/nano\/cancer-nanotechnology\/treatment\">\u5948\u7c73\u6280\u8853\u764c\u75c7\u6cbb\u7642\u548c\u6cbb\u7642<\/a> \u5f37\u8abf\u5176\u7a7f\u900f\u751f\u7406\u5c4f\u969c\u7684\u80fd\u529b\u3002\u6db2\u9ad4\u6d3b\u6aa2\uff0c\u8a0e\u8ad6\u65bc <a href=\"https:\/\/jnanobiotechnology.biomedcentral.com\/articles\/10.1186\/s12951-025-03433-8\">\u63a8\u9032\u764c\u75c7\u57fa\u56e0\u6cbb\u7642<\/a>\uff0c\u5be6\u73fe\u5373\u6642\u7a81\u8b8a\u6aa2\u6e2c\uff0c\u8207\u7cbe\u6e96\u816b\u7624\u5b78\u8da8\u52e2\u4fdd\u6301\u4e00\u81f4\u3002\u7814\u7a76\u65bc <a href=\"https:\/\/www.nature.com\/articles\/s41392-023-01642-x\">\u7528\u65bc\u764c\u75c7\u6cbb\u7642\u7684\u667a\u6167\u5948\u7c73\u9846\u7c92<\/a> \u5118\u7ba1\u6bd2\u6027\u548c\u9776\u5411\u7279\u7570\u6027\u7b49\u6311\u6230\u4ecd\u7136\u5b58\u5728\uff0c\u4f46\u5b83\u986f\u793a\u51fa\u6cbb\u7642\u8166\u8f49\u79fb\u7684\u5e0c\u671b\u3002<\/p>\n<p><strong>\u81e8\u5e8a\u8b49\u64da\u8207\u6311\u6230<\/strong>\uff1a\u8072\u7a31\u7684 ORR \u70ba 67% \u662f\u96c4\u5fc3\u52c3\u52c3\u7684\uff0c\u96d6\u7136\u65e9\u671f\u8a66\u9a57\u986f\u793a\u51fa\u5e0c\u671b\uff0c\u4f46\u9700\u8981\u66f4\u5927\u898f\u6a21\u7684\u7814\u7a76\u4f86\u9a57\u8b49\u8de8\u816b\u7624\u985e\u578b\u7684\u7642\u6548\u3002\u816b\u7624\u7570\u8cea\u6027\uff0c\u5982\u4e2d\u6240\u8ff0 <a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-023-01865-0\">\u9032\u6b65\u5948\u7c73\u6280\u8853\u4ee5\u6539\u5584\u6a19\u9776\u764c\u75c7\u6cbb\u7642<\/a>\uff0c\u53ef\u80fd\u6703\u9650\u88fd\u6210\u529f\uff0c\u9700\u8981\u7d44\u5408\u7b56\u7565\u3002<\/p>\n<h3>\u514d\u75ab\u98a8\u66b4\u6fc0\u6d3b<\/h3>\n<p><strong>\u7e3d\u7d50\u8207\u6a5f\u5236<\/strong>\uff1a\u6b64\u65b9\u6cd5\u4f7f\u7528 PD-1\/CTLA-4 \u6291\u5236\u5291\u3001\u65b0\u6297\u539f\u75ab\u82d7\u3001CAR-NK \u7d30\u80de\u548c\u5fae\u751f\u7269\u7d44\u8abf\u7bc0\u4f86\u6d3b\u5316\u591a\u5c64\u514d\u75ab\u53cd\u61c9\u3002\u5b83\u8072\u7a31 3 \u5e74\u5b58\u6d3b\u7387\u70ba 62.7%\uff08\u6539\u5584\u4e86 244%\uff09\uff0c\u5fa9\u767c\u7387\u964d\u4f4e\u4e86 85%\uff0c\u5c07\u300c\u51b7\u300d\u816b\u7624\u8f49\u8b8a\u70ba\u300c\u71b1\u300d\u816b\u7624\u3002<\/p>\n<p><strong>\u79d1\u5b78\u4f9d\u64da<\/strong>\uff1a\u806f\u5408\u514d\u75ab\u7642\u6cd5\u662f\u9818\u5148\u9818\u57df\uff0c <a href=\"https:\/\/jhoonline.biomedcentral.com\/articles\/10.1186\/s13045-021-01164-5\">\u6700\u5927\u5316\u764c\u75c7\u514d\u75ab\u6cbb\u7642\u76ca\u8655\u7684\u7d44\u5408\u7b56\u7565<\/a> \u986f\u793a\u51fa\u589e\u5f37\u7684\u53cd\u61c9\u3002\u6aa2\u67e5\u9ede\u6291\u5236\u5291\u3001\u65b0\u6297\u539f\u75ab\u82d7\u548c CAR-T\/NK \u7642\u6cd5\uff0c\u53c3\u898b <a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-025-02305-x\">\u764c\u75c7\u514d\u75ab\u6cbb\u7642\u7684\u9032\u5c55<\/a>\u3001\u63d0\u9ad8\u514d\u75ab\u8fa8\u8b58\u80fd\u529b\u3002\u5fae\u751f\u7269\u7d44\u8abf\u7bc0\uff0c\u7a81\u51fa\u986f\u793a\u65bc <a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-021-01316-8\">\u764c\u75c7\u4ee3\u8b1d\u91cd\u7de8\u7a0b\u548c\u514d\u75ab\u53cd\u61c9<\/a>\uff0c\u5f71\u97ff\u514d\u75ab\u6cbb\u7642\u7684\u7d50\u679c\uff0c\u5118\u7ba1\u5176\u4e00\u81f4\u6027\u6709\u722d\u8b70\u3002<\/p>\n<p><strong>\u81e8\u5e8a\u8b49\u64da\u8207\u6311\u6230<\/strong>\uff1a\u8072\u7a31\u7684\u751f\u5b58\u7387\u8207\u6700\u8fd1\u7684\u8a66\u9a57\u4e00\u81f4\uff0c\u4f46\u5be6\u9ad4\u7624\u7531\u65bc\u7570\u8cea\u6027\u548c\u514d\u75ab\u6291\u5236\u5fae\u74b0\u5883\u800c\u5e36\u4f86\u6311\u6230\uff0c\u5982 <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2772906024004989\">\u764c\u75c7\u514d\u75ab\u7642\u6cd5\u7684\u6700\u65b0\u9032\u5c55<\/a>\u3002\u95dc\u65bc\u5fa9\u767c\u548c\u514d\u75ab\u8a18\u61b6\u7684\u9577\u671f\u6578\u64da\u9700\u8981\u9032\u4e00\u6b65\u9a57\u8b49\u3002<\/p>\n<h3>\u6bd4\u8f03\u81e8\u5e8a\u7d50\u679c<\/h3>\n<p>\u9019\u4e9b\u6587\u4ef6\u63d0\u4f9b\u4e86\u4e00\u500b\u6bd4\u8f03\u50b3\u7d71\u7642\u6cd5\u548c\u56db\u7dad\u7642\u6cd5\u7684\u8868\u683c\uff0c\u70ba\u6e05\u695a\u8d77\u898b\uff0c\u5c07\u5176\u8907\u88fd\u5982\u4e0b\uff1a<\/p>\n<figure>\n<table class=\"has-fixed-layout\">\n<tbody>\n<tr>\n<td>\u6307\u6a19<\/td>\n<td>\u50b3\u7d71\u7684<br \/>\u6cbb\u7642<\/td>\n<td>\u56db\u7dad<br \/>\u6cbb\u7642<\/td>\n<td>\u6539\u9032<\/td>\n<\/tr>\n<tr>\n<td>\u5ba2\u89c0\u7de9\u89e3\u7387 (ORR)<\/td>\n<td>31%<\/td>\n<td>67%<\/td>\n<td>\u2191116%<\/td>\n<\/tr>\n<tr>\n<td>3 \u5e74\u5b58\u6d3b\u7387<\/td>\n<td>18%<\/td>\n<td>62.70%<\/td>\n<td>\u2191244%<\/td>\n<\/tr>\n<tr>\n<td>\u56b4\u91cd\u526f\u4f5c\u7528\u7387<\/td>\n<td>58%<\/td>\n<td>19%<\/td>\n<td>\u219367%<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/figure>\n<p>\u8868\u683c\u5f37\u8abf\u4e86\u8a72\u7642\u6cd5\u7684\u6f5b\u529b\uff0c\u4f46\u60a3\u8005\u7fa4\u9ad4\u548c\u816b\u7624\u985e\u578b\u4e4b\u9593\u7684\u5dee\u7570\u503c\u5f97\u9032\u4e00\u6b65\u7814\u7a76\u3002<\/p>\n<h2><strong>\u7d50\u8ad6<\/strong><\/h2>\n<p>\u56db\u7dad\u7121\u6bd2\u7642\u6cd5\u6574\u5408\u4e86\u89e3\u6c7a\u764c\u75c7\u8907\u96dc\u6027\u7684\u5c16\u7aef\u7b56\u7565\uff0c\u6bcf\u7a2e\u65b9\u6cd5\u90fd\u5f97\u5230\u65b0\u8208\u7814\u7a76\u7684\u652f\u6301\u3002\u7136\u800c\uff0c\u816b\u7624\u7570\u8cea\u6027\u3001\u81e8\u5e8a\u9a57\u8b49\u548c\u53ef\u8fd1\u6027\u7b49\u6311\u6230\u9700\u8981\u4e0d\u65b7\u63a2\u7d22\u3002\u5efa\u8b70\u7684\u53e3\u865f\u548c\u53e3\u865f\u65e8\u5728\u9ad4\u73fe\u8a72\u7642\u6cd5\u7684\u627f\u8afe\uff0c\u4e26\u5f15\u767c\u5c0d\u5176\u6539\u8b8a\u764c\u75c7\u6cbb\u7642\u6f5b\u529b\u7684\u9032\u4e00\u6b65\u8a0e\u8ad6\u3002<\/p>\n<h2>\u4e3b\u8981\u5f15\u6587<\/h2>\n<ul>\n<li><a href=\"https:\/\/www.nature.com\/articles\/s41573-021-00339-6\">\u7cbe\u6e96\u816b\u7624\u5b78\u6642\u4ee3\u6a19\u9776\u764c\u75c7\u4ee3\u8b1d<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2590183420300028\">\u764c\u75c7\u6cbb\u7642\u4e2d\u57fa\u65bc\u5948\u7c73\u9846\u7c92\u7684\u85e5\u7269\u8f38\u9001<\/a><\/li>\n<li><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4156829\/\">\u7bc0\u62cd\u5316\u7642<\/a><\/li>\n<li><a href=\"https:\/\/jnanobiotechnology.biomedcentral.com\/articles\/10.1186\/s12951-025-03433-8\">\u63a8\u9032\u764c\u75c7\u57fa\u56e0\u6cbb\u7642<\/a><\/li>\n<li><a href=\"https:\/\/jhoonline.biomedcentral.com\/articles\/10.1186\/s13045-021-01164-5\">\u6700\u5927\u5316\u764c\u75c7\u514d\u75ab\u6cbb\u7642\u76ca\u8655\u7684\u7d44\u5408\u7b56\u7565<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2772906024004989\">\u764c\u75c7\u514d\u75ab\u7642\u6cd5\u7684\u6700\u65b0\u9032\u5c55<\/a><\/li>\n<li><a href=\"https:\/\/www.cancer.gov\/nano\/cancer-nanotechnology\/treatment\">\u5948\u7c73\u6280\u8853\u764c\u75c7\u6cbb\u7642\u548c\u6cbb\u7642<\/a><\/li>\n<li><a href=\"https:\/\/www.nature.com\/articles\/s41392-023-01642-x\">\u7528\u65bc\u764c\u75c7\u6cbb\u7642\u7684\u667a\u6167\u5948\u7c73\u9846\u7c92<\/a><\/li>\n<li><a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-021-01316-8\">\u764c\u75c7\u4ee3\u8b1d\u91cd\u7de8\u7a0b\u548c\u514d\u75ab\u53cd\u61c9<\/a><\/li>\n<li><a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-025-02305-x\">\u764c\u75c7\u514d\u75ab\u6cbb\u7642\u7684\u9032\u5c55<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2405844024007011\">\u7bc0\u62cd\u5316\u7642\u548c\u85e5\u7269\u518d\u5229\u7528<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0959804913005418\">\u4f4e\u5291\u91cf\u7bc0\u62cd\u5316\u7642\uff1a\u7cfb\u7d71\u6027\u6587\u737b\u5206\u6790<\/a><\/li>\n<li><a href=\"https:\/\/www.lifespringcancer.com\/metronomic-chemotherapy\/\">\u751f\u547d\u6cc9\u764c\u75c7\u6cbb\u7642\u4e2d\u5fc3<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2772906024004989\">\u57fa\u65bc\u5948\u7c73\u9846\u7c92\u7684\u85e5\u7269\u50b3\u8f38\u7cfb\u7d71\u7684\u529f\u6548\u56de\u9867<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2772906024004989\">\u9032\u6b65\u5948\u7c73\u6280\u8853\u4ee5\u6539\u5584\u6a19\u9776\u764c\u75c7\u6cbb\u7642<\/a><\/li>\n<\/ul>\n<hr>\n<div class=\"ac-blog-cta\">\n<h2>\u9700\u8981\u5354\u52a9\u4e86\u89e3\u6cbb\u7642\u9078\u64c7\uff1f<\/h2>\n<p>\u6211\u5011\u7684\u60a3\u8005\u670d\u52d9\u5718\u968a\u53ef\u4ee5\u5e6b\u52a9\u60a8\u6e96\u5099\u5831\u544a\u4e26\u5b89\u6392\u9069\u7576\u7684\u5c08\u5bb6\u8aee\u8a62\u3002\u672c\u6587\u662f\u4e00\u822c\u8a0a\u606f\uff0c\u800c\u4e0d\u662f\u8a3a\u65b7\u3002<\/p>\n<p><a href=\"\/zh-hk\/appointment\/\">\u9810\u7d04\u8aee\u8a62<\/a> &nbsp;|&nbsp; <a href=\"\/zh-hk\/cancer\/\">\u63a2\u7d22\u6240\u6709\u764c\u75c7\u985e\u578b<\/a><\/p>\n<\/div>\n<p class=\"ac-blog-disclaimer\"><em>\u91ab\u7642\u514d\u8cac\u8072\u660e\uff1a\u672c\u6587\u50c5\u7528\u65bc\u4e00\u822c\u6559\u80b2\uff0c\u4e0d\u80fd\u53d6\u4ee3\u5408\u683c\u81e8\u5e8a\u91ab\u751f\u7684\u5efa\u8b70\u3002\u6cbb\u7642\u6c7a\u5b9a\u61c9\u57fa\u65bc\u500b\u4eba\u7684\u8a3a\u65b7\u3001\u5206\u671f\u3001\u75c5\u7406\u548c\u6574\u9ad4\u5065\u5eb7\u72c0\u6cc1\u3002\u5982\u679c\u60a8\u767c\u73fe\u6301\u7e8c\u6216\u4ee4\u4eba\u64d4\u6182\u7684\u75c7\u72c0\uff0c\u8acb\u5c0b\u6c42\u91ab\u7642\u8a55\u4f30\u3002<\/em><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Gestational Trophoblastic Disease (GTD) describes a rare group of tumors originating from placental tissue, specifically from cells known as trophoblasts.<\/p>","protected":false},"featured_media":227,"menu_order":37,"template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-359","cancer_type","type-cancer_type","status-publish","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/all-cancers.com\/zh-hk\/wp-json\/wp\/v2\/cancer_type\/359","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/all-cancers.com\/zh-hk\/wp-json\/wp\/v2\/cancer_type"}],"about":[{"href":"https:\/\/all-cancers.com\/zh-hk\/wp-json\/wp\/v2\/types\/cancer_type"}],"version-history":[{"count":1,"href":"https:\/\/all-cancers.com\/zh-hk\/wp-json\/wp\/v2\/cancer_type\/359\/revisions"}],"predecessor-version":[{"id":499,"href":"https:\/\/all-cancers.com\/zh-hk\/wp-json\/wp\/v2\/cancer_type\/359\/revisions\/499"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/all-cancers.com\/zh-hk\/wp-json\/wp\/v2\/media\/227"}],"wp:attachment":[{"href":"https:\/\/all-cancers.com\/zh-hk\/wp-json\/wp\/v2\/media?parent=359"}],"curies":[{"name":"\u53ef\u6fd5\u6027\u7c89\u5291","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}