{"id":373,"date":"2026-07-10T09:00:00","date_gmt":"2026-07-10T09:00:00","guid":{"rendered":"https:\/\/all-cancers.com\/cancer\/adenoid-cystic-carcinoma-acc-cancer\/"},"modified":"2026-10-29T13:38:06","modified_gmt":"2026-10-29T13:38:06","slug":"adenoid-cystic-carcinoma-acc-cancer","status":"publish","type":"cancer_type","link":"https:\/\/all-cancers.com\/zh-hk\/cancer\/adenoid-cystic-carcinoma-acc-cancer\/","title":{"rendered":"\u817a\u6a23\u56ca\u6027\u764c (ACC)"},"content":{"rendered":"<div class=\"ac-blog-article\">\n<p class=\"ac-blog-lead\"><strong>\u817a\u6a23\u56ca\u6027\u764c (ACC) \u662f\u4e00\u7a2e\u7f55\u898b\u4f46\u5177\u6709\u4fb5\u8972\u6027\u7684\u764c\u75c7\uff0c\u901a\u5e38\u767c\u751f\u5728\u817a\u9ad4\u7d44\u7e54\u4e2d\uff0c\u5c24\u5176\u5f71\u97ff\u553e\u6db2\u817a\u3002 ACC \u7684\u4e3b\u8981\u7279\u5fb5\u662f\u751f\u9577\u7de9\u6162\u548c\u5fa9\u767c\u7387\u9ad8\uff0c\u70ba\u8a3a\u65b7\u548c\u6cbb\u7642\u5e36\u4f86\u4e86\u5de8\u5927\u7684\u6311\u6230\u3002\u96d6\u7136\u9019\u7a2e\u764c\u75c7\u985e\u578b\u5728\u5168\u7403\u7bc4\u570d\u5167\u5f88\u5c11\u898b\uff0c\u4f46\u9700\u8981\u5c08\u696d\u77e5\u8b58\u548c\u91cf\u8eab\u5b9a\u5236\u7684\u6cbb\u7642\u65b9\u6cd5\u624d\u80fd\u6709\u6548\u7ba1\u7406\u3002<\/strong><\/p>\n<nav class=\"ac-blog-toc\" aria-label=\"\u672c\u6587\u5c0e\u89bd\">\n<p><strong>\u672c\u6587\u5c0e\u89bd<\/strong><\/p>\n<ul>\n<li><a href=\"#what-is-adenoid-cystic-carcinoma-acc\">\u4ec0\u9ebc\u662f\u817a\u6a23\u56ca\u6027\u764c (ACC)\uff1f<\/a><\/li>\n<li><a href=\"#causes-and-risk-factors-of-adenoid-cystic-carcinoma-acc\">\u817a\u6a23\u56ca\u6027\u764c (ACC) \u7684\u75c5\u56e0\u548c\u5371\u96aa\u56e0\u5b50<\/a><\/li>\n<li><a href=\"#symptoms-of-adenoid-cystic-carcinoma-acc\">\u817a\u6a23\u56ca\u6027\u764c (ACC) \u7684\u75c7\u72c0<\/a><\/li>\n<li><a href=\"#stages-of-adenoid-cystic-carcinoma-acc-and-survival-rates\">\u817a\u6a23\u56ca\u6027\u764c (ACC) \u7684\u5206\u671f\u548c\u5b58\u6d3b\u7387<\/a><\/li>\n<li><a href=\"#limitations-of-traditional-therapies-for-adenoid-cystic-carcinoma-acc\">\u817a\u6a23\u56ca\u6027\u764c (ACC) \u50b3\u7d71\u7642\u6cd5\u7684\u5c40\u9650\u6027<\/a><\/li>\n<\/ul>\n<\/nav>\n<h2 id=\"what-is-adenoid-cystic-carcinoma-acc\">\u4ec0\u9ebc\u662f <strong>\u817a\u6a23\u56ca\u6027\u764c (ACC)<\/strong>?<\/h2>\n<p>\u5f9e\u751f\u7269\u5b78\u89d2\u5ea6\u4f86\u770b\uff0c\u817a\u6a23\u56ca\u6027\u764c (ACC) \u8d77\u6e90\u65bc\u6392\u5217\u5728\u8eab\u9ad4\u8a31\u591a\u5167\u8868\u9762\u548c\u5916\u8868\u9762\u7684\u817a\u4e0a\u76ae\u7d30\u80de\u3002\u764c\u7d30\u80de\u7684\u4ee3\u8b1d\uff0c\u5c24\u5176\u662f\u74e6\u723e\u5821\u6548\u61c9\uff0c\u8d77\u8457\u81f3\u95dc\u91cd\u8981\u7684\u4f5c\u7528\u3002\u5177\u9ad4\u4f86\u8aaa\uff0c\u817a\u6a23\u56ca\u6027\u764c (ACC) \u764c\u7d30\u80de\u56b4\u91cd\u4f9d\u8cf4\u7570\u5e38\u7684\u8461\u8404\u7cd6\u4ee3\u8b1d\uff0c\u6d88\u8017\u8461\u8404\u7cd6\u7684\u901f\u5ea6\u6bd4\u6b63\u5e38\u7d30\u80de\u5feb\u7d04 200 \u500d\u3002\u9019\u7a2e\u52a0\u901f\u7684\u4ee3\u8b1d\u7387\u6709\u5229\u65bc\u751f\u9577\u548c\u589e\u6b96\uff0c\u4f7f\u8461\u8404\u7cd6\u4ee3\u8b1d\u6210\u70ba\u503c\u5f97\u6ce8\u610f\u7684\u6cbb\u7642\u76ee\u6a19\u3002<\/p>\n<h3 id=\"prevalence-and-epidemiology-in-hong-kong-and-asia\">\u9999\u6e2f\u548c\u4e9e\u6d32\u7684\u76db\u884c\u7387\u548c\u6d41\u884c\u75c5\u5b78<\/h3>\n<p>\u5728\u5168\u7403\u7bc4\u570d\u5167\uff0c\u6bcf\u5e74\u5831\u544a\u7d04 1,200-1,500 \u4f8b\u65b0\u767c\u817a\u6a23\u56ca\u6027\u764c (ACC) \u75c5\u4f8b\uff0c\u986f\u793a\u5176\u662f\u4e00\u7a2e\u7f55\u898b\u7684\u60e1\u6027\u816b\u7624\u3002\u5728\u4e9e\u6d32\uff0c\u5305\u62ec\u9999\u6e2f\uff0c\u5176\u76db\u884c\u7387\u540c\u6a23\u8f03\u4f4e\uff0c\u4f46\u7531\u65bc\u5176\u7368\u7279\u7684\u767c\u751f\u6a21\u5f0f\u800c\u986f\u8457\u3002\u96d6\u7136 ACC \u901a\u5e38\u5f71\u97ff 40 \u6b72\u81f3 60 \u6b72\u4e4b\u9593\u7684\u6210\u5e74\u4eba\uff0c\u4f46\u5b83\u5e7e\u4e4e\u53ef\u4ee5\u51fa\u73fe\u5728\u4efb\u4f55\u5e74\u9f61\uff0c\u81e8\u5e8a\u7d71\u8a08\u6578\u64da\u986f\u793a\u5973\u6027\u7565\u4f54\u512a\u52e2\u3002<\/p>\n<ul>\n<li>\u5168\u7403\u767c\u751f\u7387\uff1a\u6bcf\u5e74\u7d04 1,200-1,500 \u4f8b\u3002<\/li>\n<li>\u5178\u578b\u5e74\u9f61\u7bc4\u570d\uff1a40-60\u6b72\u3002<\/li>\n<li>\u6027\u5225\u512a\u52e2\uff1a\u5973\u6027\u7565\u9ad8\u3002<\/li>\n<li>\u4e9e\u6d32\u7279\u6709\u7684\u98a8\u96aa\uff1a\u6c92\u6709\u660e\u78ba\u7684\u7a2e\u65cf\u504f\u597d\u5831\u544a\uff1b\u7136\u800c\uff0c\u7531\u65bc\u7f3a\u4e4f\u8a8d\u8b58\u548c\u5fae\u5999\u7684\u75c7\u72c0\u8868\u73fe\uff0c\u5ef6\u9072\u8a3a\u65b7\u5f88\u5e38\u898b\u3002<\/li>\n<\/ul>\n<h3 id=\"signs-symptoms-and-physical-impact\">\u5fb5\u5146\u3001\u75c7\u72c0\u548c\u8eab\u9ad4\u5f71\u97ff<\/h3>\n<p>\u65e9\u671f\u8b58\u5225\u817a\u6a23\u56ca\u6027\u764c (ACC) \u5c0d\u65bc\u6539\u5584\u9810\u5f8c\u81f3\u95dc\u91cd\u8981\u3002\u4e0d\u5e78\u7684\u662f\uff0c\u7531\u65bc\u5176\u96b1\u5bc6\u7684\u751f\u9577\u6a21\u5f0f\uff0c\u75c7\u72c0\u6700\u521d\u5f80\u5f80\u986f\u5f97\u5fae\u5999\uff1a<\/p>\n<ul>\n<li>\u553e\u6db2\u817a\u3001\u53e3\u8154\u6216\u5589\u56a8\u5340\u57df\u51fa\u73fe\u7121\u75db\u6027\u816b\u8139\u6216\u816b\u584a\u3002<\/li>\n<li>\u795e\u7d93\u53d7\u7d2f\u5c0e\u81f4\u9ebb\u6728\u3001\u81c9\u90e8\u7121\u529b\u6216\u795e\u7d93\u75db\u3002<\/li>\n<li>\u541e\u56a5\u6216\u6e05\u6670\u8aaa\u8a71\u56f0\u96e3\u3002<\/li>\n<li>\u665a\u671f\u816b\u7624\u90e8\u4f4d\u6301\u7e8c\u75bc\u75db\u6216\u4e0d\u9069\u3002<\/li>\n<\/ul>\n<p>\u5728\u60c5\u7dd2\u548c\u5fc3\u7406\u4e0a\uff0c\u817a\u6a23\u56ca\u6027\u764c (ACC) \u6703\u56b4\u91cd\u5f71\u97ff\u60a3\u8005\u548c\u5bb6\u5ead\uff0c\u5c0e\u81f4\u75b2\u52de\u3001\u7126\u616e\u3001\u6182\u9b31\u548c\u793e\u4ea4\u9000\u7e2e\u3002\u5305\u62ec\u5fc3\u7406\u8aee\u5546\u5728\u5167\u7684\u5168\u9762\u652f\u6301\u7cfb\u7d71\u662f\u9999\u6e2f\u6709\u200b\u200b\u6548\u7ba1\u7406\u9019\u9805\u8ca0\u64d4\u7684\u91cd\u8981\u7d44\u6210\u90e8\u5206\u3002<\/p>\n<p>\u4e86\u89e3\u66f4\u591a\u95dc\u65bc <a href=\"\/zh-hk\/treatment-cancer\/\">\u764c\u75c7\u751f\u7269\u5b78<\/a> \u6216\u63a2\u7d22\u6e96\u78ba\u800c\u8fc5\u901f <a href=\"\/zh-hk\/our-hospital\/\">AllCancer \u7684\u8a3a\u65b7<\/a>.<\/p>\n<h2 id=\"causes-and-risk-factors-of-adenoid-cystic-carcinoma-acc\">\u817a\u6a23\u56ca\u6027\u764c (ACC) \u7684\u75c5\u56e0\u548c\u5371\u96aa\u56e0\u5b50<\/h2>\n<h3 id=\"genetic-factors-and-molecular-profiles\">\u907a\u50b3\u56e0\u7d20\u548c\u5206\u5b50\u8b5c<\/h3>\n<p>\u817a\u6a23\u56ca\u6027\u764c (ACC) \u4e2d\u7d93\u5e38\u767c\u73fe\u67d0\u4e9b\u57fa\u56e0\u7a81\u8b8a\u6216\u5206\u5b50\u8b8a\u5316\u3002\u4f8b\u5982\uff0c\u5728\u5927\u7d04 60-70% \u7684 ACC \u75c5\u4f8b\u4e2d\u89c0\u5bdf\u5230 MYB-NFIB \u878d\u5408\u57fa\u56e0\u3002\u9019\u7a2e\u878d\u5408\u6539\u8b8a\u4fc3\u9032\u7570\u5e38\u7684\u7d30\u80de\u5b58\u6d3b\u9014\u5f91\u548c\u8a0a\u865f\u50b3\u5c0e\uff0c\u5f9e\u800c\u4fc3\u9032\u816b\u7624\u751f\u9577\u548c\u6301\u7e8c\u5b58\u5728\u3002<\/p>\n<ul>\n<li>\u5e38\u898b\u57fa\u56e0\u7a81\u8b8a\uff1aMYB-NFIB\u878d\u5408\u57fa\u56e0 <strong>60-70% \u7684\u75c5\u4f8b<\/strong>.<\/li>\n<li>BRCA1\/2 \u7a81\u8b8a\u5f88\u7f55\u898b\uff0c\u4f46\u8207\u5404\u7a2e\u764c\u75c7\uff08\u5076\u723e\u5305\u62ec ACC\uff09\u7684\u5bb6\u65cf\u6613\u611f\u6027\u6709\u95dc\u3002<\/li>\n<li>\u503c\u5f97\u6ce8\u610f\u7684\u57fa\u56e0\u8868\u73fe\uff1ac-KIT \u548c EGFR \u7a81\u8b8a\u88ab\u4f5c\u70ba\u6f5b\u5728\u7684\u6cbb\u7642\u6a19\u9776\u9032\u884c\u7814\u7a76\u3002<\/li>\n<\/ul>\n<h3 id=\"environmental-and-occupational-factors\">\u74b0\u5883\u548c\u8077\u696d\u56e0\u7d20<\/h3>\n<p>\u8207\u80ba\u764c\u6216\u76ae\u819a\u764c\u7b49\u8a31\u591a\u764c\u75c7\u4e0d\u540c\uff0c\u6c92\u6709\u660e\u78ba\u7684\u74b0\u5883\u66b4\u9732\u6216\u8077\u696d\u56e0\u7d20\u8207\u817a\u6a23\u56ca\u6027\u764c (ACC) \u76f4\u63a5\u76f8\u95dc\u3002\u7136\u800c\uff0c\u6709\u9650\u7684\u7814\u7a76\u8868\u660e\u8207\u4ee5\u4e0b\u56e0\u7d20\u53ef\u80fd\u5b58\u5728\u95dc\u806f\uff1a<\/p>\n<ul>\n<li>\u66b4\u9732\u65bc\u8f3b\u5c04\uff0c\u5c24\u5176\u662f\u5148\u524d\u63a5\u53d7\u904e\u982d\u9838\u764c\u6cbb\u7642\u8f3b\u5c04\u7684\u8f3b\u5c04\u3002<\/li>\n<li>\u67d0\u4e9b\u5de5\u696d\u5316\u5b78\u54c1\uff08\u5118\u7ba1\u8b49\u64da\u4ecd\u4e0d\u78ba\u5b9a\uff09\u3002<\/li>\n<li>\u6b77\u53f2\u4e0a\u9700\u8981\u653e\u5c04\u6cbb\u7642\u7684\u91ab\u5b78\u6cbb\u7642\u3002<\/li>\n<\/ul>\n<h3 id=\"lifestyle-factors-and-metabolic-vulnerabilities\">\u751f\u6d3b\u65b9\u5f0f\u56e0\u7d20\u548c\u4ee3\u8b1d\u8106\u5f31\u6027<\/h3>\n<p>\u751f\u6d3b\u65b9\u5f0f\u56e0\u7d20\u8207 ACC \u4e4b\u9593\u7684\u660e\u78ba\u76f8\u95dc\u6027\u6975\u5c0f\u3002\u5118\u7ba1\u5982\u6b64\uff0c\u7531\u65bc\u764c\u75c7\u4ee3\u8b1d\u4f9d\u8cf4\u6027\uff0c\u95dc\u9375\u7684\u4ee3\u8b1d\u8106\u5f31\u6027\u5f15\u8d77\u4e86\u4eba\u5011\u7684\u8208\u8da3\uff1a<\/p>\n<ul>\n<li>\u9ad8\u8461\u8404\u7cd6\u6d88\u8017\u7387\uff08\u74e6\u723e\u5821\u6548\u61c9\uff09\u4fc3\u9032\u5feb\u901f\u6210\u9577\u3002<\/li>\n<li>\u5927\u7d04 50% \u7684\u75c5\u4f8b\u5b58\u5728\u9ea9\u91af\u80fa\u9178\u4f9d\u8cf4\u6027\uff0c\u652f\u6301\u6838\u82f7\u9178\u5408\u6210\u548c\u589e\u6b96\u3002<\/li>\n<li>\u7f3a\u6c27\u5fae\u74b0\u5883\u4fc3\u9032\u8840\u7ba1\u751f\u6210\u548c\u65e5\u76ca\u4fb5\u8972\u6027\u7684\u816b\u7624\u8868\u578b\u3002<\/li>\n<\/ul>\n<h3 id=\"regional-risk-factors-specific-to-hong-kong-and-asia\">\u9999\u6e2f\u548c\u4e9e\u6d32\u7279\u6709\u7684\u5340\u57df\u98a8\u96aa\u56e0\u7d20<\/h3>\n<p>\u76ee\u524d\u6b63\u5728\u9032\u884c\u7684\u6d41\u884c\u75c5\u5b78\u8abf\u67e5\u5c1a\u672a\u767c\u73fe\u9999\u6e2f\u6216\u4e9e\u6d32\u4eba\u7fa4\u5c0d\u817a\u6a23\u56ca\u6027\u764c (ACC) \u6709\u7279\u5b9a\u7684\u7a2e\u65cf\u50be\u5411\u3002\u7136\u800c\uff0c\u5728\u4e9e\u6d32\u666e\u904d\u89c0\u5bdf\u5230\u7684\u5ef6\u9072\u8a3a\u65b7\u8207\u75c5\u8b8a\u7d93\u5e38\u88ab\u5ffd\u8996\u6216\u6700\u521d\u88ab\u8aa4\u8a8d\u70ba\u662f\u826f\u6027\u75c5\u8b8a\u6709\u95dc\u3002\u66f4\u91cd\u8996\u5ba3\u50b3\u6d3b\u52d5\u548c\u9ad8\u54c1\u8cea\u7684\u91ab\u7642\u4fdd\u5065\u670d\u52d9\u4ecd\u7136\u662f\u53d6\u5f97\u66f4\u597d\u7d50\u679c\u7684\u95dc\u9375\u3002<\/p>\n<p>\u5c0d\u65bc\u4efb\u4f55\u767c\u73fe\u6301\u7e8c\u3001\u4e0d\u5c0b\u5e38\u7684\u817a\u9ad4\u816b\u8139\u6216\u795e\u7d93\u4e0d\u9069\u7684\u4eba\u4f86\u8aaa\uff0c\u53ca\u6642\u5c31\u91ab\u81f3\u95dc\u91cd\u8981\u3002 AllCancer \u9f13\u52f5\u65e9\u671f\u7be9\u6aa2\uff0c\u63a1\u7528\u6211\u5011\u6700\u5148\u9032\u7684\u4ee3\u8b1d\u816b\u7624\u5b78\u8a08\u5283\u7684\u4eba\u53ef\u4ee5\u986f\u8457\u6539\u5584\u9810\u5f8c\u3002<\/p>\n<p>\u4e86\u89e3\u6211\u5011\u7684\u9769\u547d\u6027\u7684 <a href=\"\/zh-hk\/treatment-cancer\/\">4D \u7642\u6cd5\u6539\u8b8a\u817a\u6a23\u56ca\u6027\u764c (ACC) \u6cbb\u7642<\/a> \u5177\u6709\u8afe\u8c9d\u723e\u734e\u7372\u734e\u7814\u7a76\u652f\u63f4\u6280\u8853\u7684\u9078\u9805\u3002<\/p>\n<h3 id=\"preventive-measures-and-early-detection-strategies\">\u9810\u9632\u63aa\u65bd\u548c\u65e9\u671f\u767c\u73fe\u7b56\u7565<\/h3>\n<p>\u5118\u7ba1\u7531\u65bc\u75c5\u56e0\u4e0d\u660e\uff0c\u76ee\u524d\u91dd\u5c0d\u817a\u6a23\u56ca\u6027\u764c\uff08ACC\uff09\u7684\u5177\u9ad4\u9810\u9632\u65b9\u6cd5\u6709\u9650\uff0c\u4f46\u4e00\u822c\u7684\u9810\u9632\u6027\u5065\u5eb7\u884c\u70ba\u4ecd\u5c0d\u6574\u9ad4\u5065\u5eb7\u5927\u6709\u88e8\u76ca\uff1a<\/p>\n<ul>\n<li>\u5b9a\u671f\u9ad4\u6aa2\uff0c\u91cd\u9ede\u662f\u982d\u90e8\u548c\u9838\u90e8\u8a55\u4f30\u3002<\/li>\n<li>\u767c\u73fe\u6301\u7e8c\u6027\u816b\u584a\u6216\u795e\u7d93\u76f8\u95dc\u75c7\u72c0\u5f8c\u7acb\u5373\u9032\u884c\u8a3a\u65b7\u7be9\u6aa2\u3002<\/li>\n<li>\u5021\u5c0e\u63d0\u9ad8\u516c\u773e\u5c0d ACC \u7b49\u7f55\u898b\u817a\u764c\u7684\u8a8d\u8b58\u3002<\/li>\n<\/ul>\n<p>AllCancer \u5f37\u70c8\u5021\u5c0e\u7a4d\u6975\u4e3b\u52d5\u7684\u5065\u5eb7\u7dad\u8b77\uff0c\u4e26\u9f13\u52f5\u5c0d\u7570\u5e38\u75c7\u72c0\u7acb\u5373\u5c31\u91ab\uff0c\u9019\u7b26\u5408\u6211\u5011\u7684\u4f7f\u547d\uff0c\u5373\u5230 2025 \u5e74\u5c07\u817a\u6a23\u56ca\u6027\u764c (ACC) \u7b49\u764c\u75c7\u8f49\u8b8a\u70ba\u53ef\u63a7\u5236\u7684\u6162\u6027\u75be\u75c5\u3002<\/p>\n<h2 id=\"symptoms-of-adenoid-cystic-carcinoma-acc\">\u817a\u6a23\u56ca\u6027\u764c (ACC) \u7684\u75c7\u72c0<\/h2>\n<p>\u53ca\u65e9\u8b58\u5225\u817a\u6a23\u56ca\u6027\u764c (ACC) \u7684\u75c7\u72c0\u53ef\u4ee5\u986f\u8457\u6539\u5584\u6cbb\u7642\u7d50\u679c\u3002\u75c7\u72c0\u6839\u64da\u816b\u7624\u4f4d\u7f6e\u548c\u75be\u75c5\u968e\u6bb5\u800c\u6709\u6240\u4e0d\u540c\uff0c\u53cd\u6620\u4e86\u816b\u7624\u751f\u7269\u5b78\uff0c\u4f8b\u5982\u751f\u9577\u901f\u5ea6\u3001\u9644\u8fd1\u7d44\u7e54\u7684\u6d78\u6f64\u548c\u8f49\u79fb\u6f5b\u529b\u3002\u4ee5\u4e0b\u662f\u60a3\u8005\u5728\u4e0d\u540c\u968e\u6bb5\u53ef\u80fd\u51fa\u73fe\u7684\u5e38\u898b\u75c7\u72c0\u7684\u6982\u8ff0\u3002<\/p>\n<h3 id=\"common-symptoms-of-adenoid-cystic-carcinoma-acc\">\u817a\u6a23\u56ca\u6027\u764c (ACC) \u7684\u5e38\u898b\u75c7\u72c0<\/h3>\n<ul>\n<li>\u76ae\u4e0b\u6216\u817a\u9ad4\u5167\u53ef\u611f\u89ba\u5230\u7684\u816b\u584a\u6216\u816b\u584a<\/li>\n<li>\u56e0\u795e\u7d93\u53d7\u7d2f\u800c\u5c0e\u81f4\u53d7\u5f71\u97ff\u5340\u57df\u5468\u570d\u75bc\u75db\u6216\u9ebb\u6728<\/li>\n<li>\u541e\u56a5\u56f0\u96e3\uff08\u5982\u679c\u816b\u7624\u4f4d\u65bc\u5589\u56a8\u6216\u553e\u6db2\u817a\u9644\u8fd1\uff09<\/li>\n<li>\u8a00\u8a9e\u6216\u8072\u97f3\u7684\u8b8a\u5316\uff08\u5f71\u97ff\u53e3\u8154\u6216\u5589\u90e8\u7684\u816b\u7624\uff09<\/li>\n<li>\u7531\u65bc\u8166\u795e\u7d93\u53d7\u640d\u800c\u5c0e\u81f4\u81c9\u90e8\u7121\u529b\u6216\u7671\u7613<\/li>\n<li>\u6301\u7e8c\u6027\u9f3b\u585e\u6216\u9f3b\u7ac7\u554f\u984c\uff08ACC \u5f71\u97ff\u9f3b\u8154\uff09<\/li>\n<li>\u53e3\u8154\u6216\u9f3b\u9053\u51fa\u8840\uff08\u7531\u65bc\u9ecf\u819c\u6f70\u760d\uff09<\/li>\n<li>\u75c5\u7076\u9644\u8fd1\u816b\u8139\u6216\u7570\u5e38\u611f\u89ba<\/li>\n<li>\u5118\u7ba1\u4f11\u606f\u4ecd\u6162\u6027\u75b2\u52de<\/li>\n<li>\u98df\u617e\u4e0d\u632f\u5c0e\u81f4\u4e0d\u660e\u539f\u56e0\u7684\u9ad4\u91cd\u6e1b\u8f15<\/li>\n<\/ul>\n<h3 id=\"stage-dependent-symptoms-of-adenoid-cystic-carcinoma-acc\">\u817a\u6a23\u56ca\u6027\u764c (ACC) \u7684\u5206\u671f\u76f8\u95dc\u75c7\u72c0<\/h3>\n<h4>\u65e9\u671f\u75c7\u72c0<\/h4>\n<ul>\n<li>\u5c0f\u800c\u7121\u75db\u7684\u816b\u584a\u901a\u5e38\u5728\u4e0d\u89f8\u8a3a\u7684\u60c5\u6cc1\u4e0b\u4e0d\u6613\u5bdf\u89ba<\/li>\n<li>\u53d7\u5f71\u97ff\u5340\u57df\u6709\u8f15\u5fae\u4e0d\u9069\u6216\u9593\u6b47\u6027\u9ebb\u6728<\/li>\n<li>\u8f15\u5fae\u541e\u56a5\u56f0\u96e3\uff0c\u5c24\u5176\u662f\u5403\u56fa\u9ad4\u98df\u7269\u6642\u8f03\u660e\u986f<\/li>\n<\/ul>\n<h4>\u4e2d\u671f\u75c7\u72c0<\/h4>\n<ul>\n<li>\u8f03\u5927\u7684\u53ef\u89f8\u53ca\u816b\u584a\uff0c\u53ef\u80fd\u6703\u8b8a\u5f97\u75bc\u75db<\/li>\n<li>\u66f4\u660e\u986f\u7684\u4e0d\u9069\uff0c\u5305\u62ec\u6301\u7e8c\u7684\u9ebb\u6728\u6216\u523a\u75db\u611f<\/li>\n<li>\u60a3\u8005\u8a3b\u610f\u5230\u5c3a\u5bf8\u589e\u5927\u7684\u53ef\u898b\u6027<\/li>\n<li>\u75c7\u72c0\u59cb\u7d42\u6bd4\u8f03\u9ebb\u7169\uff0c\u4f46\u53ef\u80fd\u4ecd\u7136\u5f88\u6eab\u548c\uff0c\u6700\u521d\u53ef\u4ee5\u6d88\u9664\u3002<\/li>\n<\/ul>\n<h4>\u665a\u671f\u548c\u665a\u671f\u75c7\u72c0<\/h4>\n<ul>\n<li>\u56b4\u91cd\u7684\u795e\u7d93\u53d7\u7d2f\u5c0e\u81f4\u6162\u6027\u3001\u56b4\u91cd\u7684\u75bc\u75db\u6216\u7671\u7613<\/li>\n<li>\u541e\u56a5\u56f0\u96e3\uff08\u541e\u56a5\u56f0\u96e3\uff09\u548c\u6e05\u6670\u8aaa\u8a71<\/li>\n<li>\u7531\u65bc\u529f\u80fd\u53d7\u640d\u6216\u963b\u585e\u800c\u5c0e\u81f4\u9ad4\u91cd\u6025\u5287\u4e0b\u964d\u548c\u71df\u990a\u4e0d\u8db3<\/li>\n<li>\u816b\u7624\u6f70\u760d\u548c\u9ecf\u819c\u90e8\u4f4d\u6301\u7e8c\u51fa\u8840<\/li>\n<li>\u8f49\u79fb\u75c7\u72c0\u5305\u62ec\u54b3\u55fd\uff08\u80ba\u8f49\u79fb\uff09\u3001\u9aa8\u75db\uff08\u9aa8\u9abc\u8f49\u79fb\uff09\u6216\u9ec3\u75b8\uff08\u809d\u81df\u53d7\u7d2f\uff09<\/li>\n<li>\u865b\u5f31\u548c\u75b2\u52de\u52a0\u5287\uff0c\u56b4\u91cd\u5f71\u97ff\u751f\u6d3b\u8cea\u91cf<\/li>\n<\/ul>\n<p>\u65e9\u671f\u8a55\u4f30\u548c\u8a3a\u65b7\u6e2c\u8a66\u5c0d\u65bc\u6709\u6548\u6cbb\u7642\u817a\u6a23\u56ca\u6027\u764c (ACC) \u81f3\u95dc\u91cd\u8981\u3002\u5982\u679c\u60a8\u767c\u73fe\u4efb\u4f55\u9019\u4e9b\u65e9\u671f\u8de1\u8c61\uff0c\u8acb\u7acb\u5373\u5c0b\u6c42\u91ab\u7642\u8a55\u4f30\uff0c\u4ee5\u6539\u5584\u60a8\u7684\u6cbb\u7642\u7d50\u679c\u3002 <a href=\"\/zh-hk\/our-hospital\/\">\u5728\u6b64\u63a2\u7d22 ACC \u7684\u8a3a\u65b7\u65b9\u6cd5\u3002<\/a><\/p>\n<h2 id=\"stages-of-adenoid-cystic-carcinoma-acc-and-survival-rates\">\u817a\u6a23\u56ca\u6027\u764c (ACC) \u7684\u5206\u671f\u548c\u5b58\u6d3b\u7387<\/h2>\n<p>\u817a\u6a23\u56ca\u6027\u764c\uff08ACC\uff09\u7684\u9810\u5f8c\u5728\u5f88\u5927\u7a0b\u5ea6\u4e0a\u53d6\u6c7a\u65bc\u53ca\u6642\u8b58\u5225\u548c\u8a3a\u65b7\u5206\u671f\u3002\u91dd\u5c0d\u9999\u6e2f\u548c\u4e9e\u6d32\u7684\u7814\u7a76\u986f\u793a\u51fa\u4e0d\u540c\u7684\u7d50\u679c\uff0c\u5f37\u8abf\u65e9\u671f\u4ecb\u5165\u548c\u5148\u9032\u7684\u91ab\u7642\u57fa\u790e\u8a2d\u65bd\u3002<\/p>\n<h3 id=\"stage-1-adenoid-cystic-carcinoma-acc\">\u7b2c\u4e00\u968e\u6bb5 \u2013 \u817a\u6a23\u56ca\u6027\u764c (ACC)<\/h3>\n<p>\u521d\u59cb\u968e\u6bb5 ACC \u901a\u5e38\u4fb7\u9650\u65bc\u4e00\u500b\u5c0f\u5340\u57df\uff0c\u5c1a\u672a\u5f71\u97ff\u9130\u8fd1\u7684\u89e3\u5256\u90e8\u4f4d\u6216\u6dcb\u5df4\u7d50\u3002\u5178\u578b\u7279\u5fb5\u5305\u62ec\uff1a<\/p>\n<ul>\n<li>\u5c40\u9650\u6027\u3001\u55ae\u4e00\u816b\u7624\uff0c\u76f4\u5f91\u901a\u5e38\u5c0f\u65bc 2 \u5398\u7c73<\/li>\n<li>\u7121\u5c40\u90e8\u64f4\u6563\u6216\u6dcb\u5df4\u7d50\u5f71\u97ff\u7684\u8b49\u64da<\/li>\n<\/ul>\n<p>\u6cbb\u7642\u4e3b\u8981\u5305\u62ec\u624b\u8853\u5207\u9664\uff0c\u96a8\u5f8c\u901a\u5e38\u9032\u884c\u5c40\u90e8\u653e\u5c04\u6cbb\u7642\u4ee5\u9632\u6b62\u5fa9\u767c\u3002\u5340\u57df\u6578\u64da\u652f\u6301\u65e9\u671f\u6aa2\u6e2c\u7684\u975e\u5e38\u7a4d\u6975\u7684\u9810\u5f8c\uff0c\u986f\u793a\u8a3a\u65b7\u5f8c 5 \u5e74\u5b58\u6d3b\u7387\u8d85\u904e 90%\u3002<\/p>\n<h3 id=\"stage-2-adenoid-cystic-carcinoma-acc\">\u7b2c 2 \u671f \u2013 \u817a\u6a23\u56ca\u6027\u764c (ACC)<\/h3>\n<p>\u5728\u9019\u500b\u4e2d\u9593\u968e\u6bb5\uff0c\u816b\u7624\u958b\u59cb\u8868\u73fe\u51fa\u660e\u986f\u7684\u7279\u5fb5\uff1a<\/p>\n<ul>\n<li>\u816b\u7624\u5927\u65bc2\u5398\u7c73\uff0c\u50c5\u9650\u65bc\u5c40\u90e8\u5340\u57df<\/li>\n<li>\u7121\u6dcb\u5df4\u7d50\u53d7\u7d2f\u6216\u6dcb\u5df4\u7d50\u53d7\u7d2f\u6975\u5c11<\/li>\n<li>\u795e\u7d93\u6d78\u6f64\u5c0e\u81f4\u4e2d\u5ea6\u75c7\u72c0\u7684\u53ef\u80fd\u6027\u589e\u52a0<\/li>\n<\/ul>\n<p>\u6cbb\u7642\u6703\u7a0d\u5fae\u52a0\u5f37\uff0c\u901a\u5e38\u6d89\u53ca\u624b\u8853\u4ecb\u5165\u8207\u653e\u5c04\u6cbb\u7642\u76f8\u7d50\u5408\uff0c\u4ee5\u78ba\u4fdd\u6839\u9664\u3002\u4e9e\u6d32\u5340\u57df\u6578\u64da\u986f\u793a 70-85% \u7684 5 \u5e74\u5b58\u6d3b\u7387\uff0c\u5f37\u70c8\u5f37\u8abf\u4e86\u5728\u4e3b\u8981\u6cbb\u7642\u5f8c\u6301\u7e8c\u76e3\u6e2c\u60a3\u8005\u7684\u5fc5\u8981\u6027\u3002<\/p>\n<h3 id=\"stage-3-adenoid-cystic-carcinoma-acc\">\u7b2c 3 \u671f \u2013 \u817a\u6a23\u56ca\u6027\u764c (ACC)<\/h3>\n<p>\u968e\u6bb5 3 \u8868\u793a\u665a\u671f\u5c40\u90e8\u75be\u75c5\uff0c\u7ba1\u7406\u66f4\u52a0\u8907\u96dc\uff1a<\/p>\n<ul>\n<li>\u5b58\u5728\u660e\u986f\u7684\u9130\u8fd1\u7d44\u7e54\u6d78\u6f64\u6216\u795e\u7d93\u53d7\u7d2f<\/li>\n<li>\u5340\u57df\u6dcb\u5df4\u7d50\u958b\u59cb\u51fa\u73fe\u53d7\u7d2f\uff0c\u4f46\u6c92\u6709\u9060\u7aef\u5668\u5b98\u8f49\u79fb<\/li>\n<li>\u816b\u7624\u7684\u75c7\u72c0\u548c\u529f\u80fd\u640d\u5bb3\u7684\u91cd\u8981\u904e\u7a0b\u65e5\u76ca\u589e\u591a<\/li>\n<\/ul>\n<p>\u7d9c\u5408\u591a\u6a21\u5f0f\u6cbb\u7642\u901a\u5e38\u5305\u62ec\u5ee3\u6cdb\u7684\u624b\u8853\u3001\u653e\u5c04\u6cbb\u7642\u548c\u6f5b\u5728\u7684\u5168\u8eab\u8f14\u52a9\u6cbb\u7642\u3002\u5df2\u767c\u8868\u7684\u9999\u6e2f\u548c\u4e9e\u6d32\u7814\u7a76\u5f37\u8abf\uff0c\u7b2c 3 \u671f\u817a\u6a23\u56ca\u6027\u764c (ACC) \u7684 5 \u5e74\u5b58\u6d3b\u7387\u7d04\u70ba 50-70%\uff0c\u53d6\u6c7a\u65bc\u6700\u4f73\u7684\u591a\u6a21\u5f0f\u6cbb\u7642\u3002<\/p>\n<h3 id=\"stage-4-adenoid-cystic-carcinoma-acc\">\u7b2c 4 \u671f \u2013 \u817a\u6a23\u56ca\u6027\u764c (ACC)<\/h3>\n<p>\u968e\u6bb5 4 \u4ee3\u8868\u8f49\u79fb\u6027 ACC\uff0c\u986f\u793a\u75be\u75c5\u5df2\u64f4\u6563\u5230\u8f03\u9060\u7684\u5730\u5340\uff1a<\/p>\n<ul>\n<li>\u8f49\u79fb\u6027\u816b\u7624\u7684\u8b49\u64da\uff0c\u5c24\u5176\u662f\u80ba\u3001\u809d\u3001\u9aa8\u6216\u8166\u4e2d\u7684\u8f49\u79fb\u6027\u816b\u7624<\/li>\n<li>\u75c7\u72c0\u56b4\u91cd\u4e14\u751f\u6d3b\u54c1\u8cea\u660e\u986f\u53d7\u640d<\/li>\n<li>\u66f4\u8907\u96dc\u7684\u7ba1\u7406\u9700\u8981\u5148\u9032\u7684\u7cfb\u7d71\u6cbb\u7642\u548c\u652f\u6301\u6027\u8b77\u7406\u670d\u52d9<\/li>\n<\/ul>\n<p>\u5118\u7ba1\u7b2c\u56db\u968e\u6bb5\u7684\u9810\u5f8c\u53ef\u80fd\u5177\u6709\u6311\u6230\u6027\uff0c\u4f46\u7cbe\u6e96\u91ab\u5b78\u6280\u8853\u3001\u6a19\u9776\u6cbb\u7642\u548c\u57fa\u65bc\u4ee3\u8b1d\u7684\u6cbb\u7642\u7b49\u6700\u65b0\u9032\u5c55\u73fe\u5728\u70ba\u9577\u671f\u7ba1\u7406\u665a\u671f ACC \u5e36\u4f86\u4e86\u5e0c\u671b\u3002\u5728\u91dd\u5c0d\u4e9e\u6d32\u7684\u7814\u7a76\u4e2d\uff0c\u9ad8\u968e\u8a3a\u65b7\u5f8c 3 \u81f3 5 \u5e74\u7684\u5b58\u6d3b\u7387\u5e73\u5747\u70ba 20-30%\uff0c\u51f8\u986f\u4e86\u65e9\u671f\u4ecb\u5165\u548c 4D \u4ee3\u8b1d\u816b\u7624\u7642\u6cd5\u7b49\u5275\u65b0\u6cbb\u7642\u7684\u91cd\u8981\u6027\u3002 <a href=\"\/zh-hk\/treatment-cancer\/\">\u4e86\u89e3\u6709\u95dc\u9ad8\u7d1a ACC \u6cbb\u7642\u65b9\u6848\u7684\u66f4\u591a\u8cc7\u8a0a\u3002<\/a><\/p>\n<h2 id=\"limitations-of-traditional-therapies-for-adenoid-cystic-carcinoma-acc\">\u817a\u6a23\u56ca\u6027\u764c (ACC) \u50b3\u7d71\u7642\u6cd5\u7684\u5c40\u9650\u6027<\/h2>\n<h3 id=\"chemotherapy-s-limited-efficacy-and-toxicity-in-adenoid-cystic-carcinoma-acc\">\u5316\u7642\u5c0d\u817a\u6a23\u56ca\u6027\u764c (ACC) \u7684\u6709\u9650\u7642\u6548\u548c\u6bd2\u6027<\/h3>\n<p>\u5316\u7642\u4ecd\u7136\u662f\u4e3b\u6d41\u7684\u764c\u75c7\u6cbb\u7642\u65b9\u6cd5\u3002\u7136\u800c\uff0c\u5c0d\u65bc\u817a\u6a23\u56ca\u6027\u764c\uff08ACC\uff09\uff0c\u5316\u7642\u7684\u7642\u6548\u4f4e\u5f97\u4ee4\u4eba\u5931\u671b\uff0c\u5c24\u5176\u662f\u5728\u665a\u671f\u8f49\u79fb\u671f\u3002\u50b3\u7d71\u5316\u7642\u6cbb\u7642\u8f49\u79fb\u6027 ACC \u7684\u6574\u9ad4\u5ba2\u89c0\u7de9\u89e3\u7387 (ORR) \u4f4e\u5f97\u9a5a\u4eba\uff0c\u4f4e\u65bc 21%\u3002\u6b64\u5916\uff0c\u5316\u7642\u60a3\u8005\u7d93\u5e38\u7d93\u6b77\u56b4\u91cd\u7684\u4e0d\u826f\u53cd\u61c9\uff0c\u5f71\u97ff\u4ed6\u5011\u7684\u6574\u9ad4\u6cbb\u7642\u9ad4\u9a57\u548c\u751f\u6d3b\u54c1\u8cea\u3002<\/p>\n<ul>\n<li>\u7d04 78% \u63a5\u53d7\u5316\u7642\u7684\u60a3\u8005\u6703\u51fa\u73fe\u9aa8\u9ad3\u6291\u5236\u3002<\/li>\n<li>\u5fc3\u81df\u6bd2\u6027\u5f71\u97ff\u9ad8\u9054 23% \u7684\u60a3\u8005\uff0c\u8207\u9577\u671f\u767c\u751f\u7387\u6709\u986f\u8457\u76f8\u95dc\u3002<\/li>\n<li>\u56b4\u91cd\u75b2\u52de\u548c\u5641\u5fc3\u5927\u5927\u964d\u4f4e\u4e86\u60a3\u8005\u5c0d\u9019\u4e9b\u7a4d\u6975\u7642\u6cd5\u7684\u4f9d\u5f9e\u6027\u548c\u6574\u9ad4\u8010\u53d7\u6027\u3002<\/li>\n<li>\u300aJAMA Oncology 2023\u300b\u5f37\u8abf\u5316\u7642\u5f8c\u7e7c\u767c\u6027\u764c\u75c7\u98a8\u96aa\u589e\u52a0\u4e86 300%\uff0c\u4ee4\u4eba\u9707\u9a5a\u3002<\/li>\n<\/ul>\n<p>\u9019\u4e9b\u986f\u8457\u7684\u4e0d\u826f\u53cd\u61c9\u51f8\u986f\u4e86\u65b0\u7684\u6cbb\u7642\u7b56\u7565\u7684\u5fc5\u8981\u6027\uff0c\u8a72\u7b56\u7565\u53ef\u4ee5\u6700\u5927\u9650\u5ea6\u5730\u6e1b\u5c11\u6bd2\u6027\uff0c\u540c\u6642\u589e\u5f37\u764c\u7d30\u80de\u9776\u5411\u6027\u2014\u2014\u5c24\u5176\u8207\u9999\u6e2f\u548c\u4e9e\u6d32\u7684\u60a3\u8005\u76f8\u95dc\uff0c\u56e0\u70ba\u9019\u4e9b\u5730\u5340\u7684\u885b\u751f\u8cc7\u6e90\u548c\u53ca\u6642\u5e79\u9810\u53ef\u80fd\u6703\u5e36\u4f86\u984d\u5916\u7684\u6311\u6230\u3002<\/p>\n<h3 id=\"radiotherapy-induced-complications-in-adenoid-cystic-carcinoma-acc\">\u817a\u6a23\u56ca\u6027\u764c (ACC) \u653e\u5c04\u6cbb\u7642\u5f15\u8d77\u7684\u4f75\u767c\u75c7<\/h3>\n<p>\u653e\u5c04\u6cbb\u7642\u4ecd\u662f\u6cbb\u7642\u817a\u6a23\u56ca\u6027\u764c\u4e0d\u53ef\u6216\u7f3a\u7684\u4e00\u90e8\u5206\uff0c\u901a\u5e38\u5728\u8853\u5f8c\u4f7f\u7528\u3002\u7136\u800c\uff0c\u5b58\u5728\u4e00\u4e9b\u56b4\u91cd\u7684\u9650\u5236\uff0c\u6703\u986f\u8457\u5f71\u97ff\u60a3\u8005\u7684\u6cbb\u7642\u7d50\u679c\u3002\u63a5\u53d7\u653e\u5c04\u6cbb\u7642\u53ef\u80fd\u6703\u5c0d\u5468\u570d\u6b63\u5e38\u7d44\u7e54\u9020\u6210\u6301\u4e45\u640d\u50b7\u548c\u529f\u80fd\u969c\u7919\uff0c\u901a\u5e38\u6703\u51fa\u73fe\u56b4\u91cd\u7684\u4f75\u767c\u75c7\uff1a<\/p>\n<ul>\n<li>\u8d85\u904e 50% \u7684\u63a5\u53d7\u9ad8\u5291\u91cf\u653e\u5c04\u6cbb\u7642\u7684\u60a3\u8005\u6703\u51fa\u73fe\u7d44\u7e54\u7e96\u7dad\u5316\uff0c\u5c0e\u81f4\u5668\u5b98\u548c\u7d44\u7e54\u529f\u80fd\u4e0b\u964d\u3002<\/li>\n<li>\u6162\u6027\u9ecf\u819c\u708e\u5f71\u97ff\u7d04 42% \u7684\u60a3\u8005\uff0c\u56b4\u91cd\u5f71\u97ff\u98f2\u98df\u548c\u8aaa\u8a71\u7b49\u65e5\u5e38\u6d3b\u52d5\u3002<\/li>\n<li>\u653e\u5c04\u6cbb\u7642\u76f8\u95dc\u7684\u795e\u7d93\u640d\u50b7\u6703\u5c0e\u81f4\u6301\u7e8c\u7684\u795e\u7d93\u6027\u75bc\u75db\uff0c\u986f\u8457\u964d\u4f4e\u60a3\u8005\u7684\u751f\u6d3b\u54c1\u8cea\u3002<\/li>\n<li>\u6b64\u5916\uff0c\u6b63\u5982\u8457\u540d\u816b\u7624\u5b78\u7814\u7a76\u4e00\u81f4\u5831\u5c0e\u7684\u90a3\u6a23\uff0c\u9ad8\u5291\u91cf\u8f3b\u5c04\u66b4\u9732\u986f\u8457\u589e\u52a0\u7e7c\u767c\u6027\u60e1\u6027\u816b\u7624\u7684\u98a8\u96aa\u3002<\/li>\n<\/ul>\n<p>\u9451\u65bc\u9999\u6e2f\u8001\u5e74\u4eba\u53e3\u7684\u4e0d\u65b7\u589e\u52a0\u548c ACC \u767c\u75c5\u7387\u7684\u4e0a\u5347\uff0c\u9019\u4e9b\u4f75\u767c\u75c7\u7684\u56b4\u91cd\u7a0b\u5ea6\u548c\u6301\u7e8c\u6642\u9593\u9700\u8981\u4ed4\u7d30\u8003\u616e\u6cbb\u7642\u7b56\u7565\uff0c\u4ee5\u9632\u6b62\u6b64\u985e\u4f7f\u4eba\u8870\u5f31\u7684\u526f\u4f5c\u7528\u3002<\/p>\n<h3 id=\"surgical-treatment-risks-and-limitations-for-adenoid-cystic-carcinoma-acc\">\u817a\u6a23\u56ca\u6027\u764c (ACC) \u7684\u624b\u8853\u6cbb\u7642\u98a8\u96aa\u548c\u5c40\u9650\u6027<\/h3>\n<p>\u624b\u8853\u5207\u9664\u4ecd\u662f\u817a\u6a23\u56ca\u6027\u764c\u6cbb\u7642\u7b56\u7565\u7684\u57fa\u77f3\u65b9\u6cd5\u3002\u7136\u800c\uff0c\u4e00\u4e9b\u969c\u7919\u963b\u7919\u4e86\u5176\u5ee3\u6cdb\u61c9\u7528\u3002<\/p>\n<ul>\n<li>\u7531\u65bc\u5fa9\u767c\uff0c\u901a\u5e38\u9700\u8981\u91cd\u8907\u624b\u8853\u5e79\u9810\uff0c\u5f9e\u800c\u589e\u52a0\u5c0d\u56b4\u91cd\u611f\u67d3\u7684\u6613\u611f\u6027\uff0c\u64da\u5831\u9053\uff0c\u6839\u64da\u60a3\u8005\u4ff1\u9ad4\u56e0\u7d20\uff0c\u98a8\u96aa\u767c\u751f\u7387\u5728 8% \u81f3 15% \u4e4b\u9593\u3002<\/li>\n<li>\u8907\u96dc\u7684\u5916\u79d1\u624b\u8853\u6703\u589e\u52a0\u6f5b\u5728\u7684\u4f75\u767c\u75c7\uff0c\u4f8b\u5982\u50b7\u53e3\u7652\u5408\u53d7\u640d\uff0c\u9019\u53ef\u80fd\u6703\u4f7f\u4f4f\u9662\u6642\u9593\u5ef6\u9577 2-4 \u9031\uff0c\u5f9e\u800c\u5927\u5927\u589e\u52a0\u91ab\u7642\u8cbb\u7528\u3002<\/li>\n<li>\u8853\u5f8c\u795e\u7d93\u640d\u50b7\u901a\u5e38\u6703\u5c0e\u81f4\u60a3\u8005\u9577\u671f\u529f\u80fd\u969c\u7919\u548c\u6162\u6027\u75bc\u75db\uff0c\u5f9e\u800c\u5927\u5927\u964d\u4f4e\u65e5\u5e38\u529f\u80fd\u3002<\/li>\n<\/ul>\n<p>\u5728\u9999\u6e2f\u7b49\u4eba\u53e3\u7a20\u5bc6\u7684\u57ce\u5e02\uff0c\u624b\u8853\u7684\u8907\u96dc\u6027\u548c\u6f2b\u9577\u7684\u6062\u5fa9\u6642\u9593\u7d66\u91ab\u7642\u4fdd\u5065\u8cc7\u6e90\u548c\u60a3\u8005\u7d93\u6fdf\u7a69\u5b9a\u6027\u5e36\u4f86\u4e86\u8ca0\u64d4\uff0c\u51f8\u986f\u4e86\u5c0d\u6ce8\u91cd\u5b89\u5168\u548c\u5feb\u901f\u6062\u5fa9\u7684\u5275\u65b0\u6cbb\u7642\u7684\u8feb\u5207\u9700\u6c42\u3002<\/p>\n<h3 id=\"metabolic-resistance-mechanisms-understanding-treatment-resistance-in-adenoid-cy\">\u4ee3\u8b1d\u6297\u85e5\u6027\u6a5f\u5236\uff1a\u4e86\u89e3\u817a\u6a23\u56ca\u6027\u764c (ACC) \u7684\u6cbb\u7642\u6297\u85e5\u6027<\/h3>\n<p>\u764c\u7d30\u80de\uff0c\u5c24\u5176\u662f\u817a\u6a23\u56ca\u6027\u764c\uff0c\u5c0d\u50b3\u7d71\u6cbb\u7642\u8868\u73fe\u51fa\u5f37\u5927\u7684\u9069\u61c9\u6027\u62b5\u6297\u6a5f\u5236\u3002\u9019\u4e9b\u7d30\u80de\u5229\u7528\u5347\u9ad8\u7684\u4ee3\u8b1d\u6d3b\u52d5\uff08\u5c24\u5176\u662f\u74e6\u4f2f\u683c\u6548\u61c9\uff09\u4f86\u7dad\u6301\u764c\u75c7\u589e\u751f\u548c\u6cbb\u7642\u6297\u85e5\u6027\u3002<\/p>\n<ul>\n<li>ACC \u764c\u7d30\u80de\u7684 DNA \u4fee\u5fa9\u9176\u6d3b\u6027\u589e\u52a0\u9ad8\u9054 400%\uff0c\u6709\u52a9\u65bc\u5feb\u901f\u4fee\u5fa9\u6cbb\u7642\u5f15\u8d77\u7684\u907a\u50b3\u640d\u50b7\u4e26\u4fc3\u9032\u5feb\u901f\u6297\u85e5\u6027\u3002<\/li>\n<li>\u9019\u4e9b\u60e1\u6027\u7d30\u80de\u8868\u73fe\u51fa\u56b4\u91cd\u7684\u8461\u8404\u7cd6\u4f9d\u8cf4\u6027\uff0c\u6d88\u8017\u8461\u8404\u7cd6\u7684\u901f\u5ea6\u6bd4\u6b63\u5e38\u7d30\u80de\u9ad8\u51fa\u8fd1 200 \u500d\u3002\u9019\u7a2e\u8461\u8404\u7cd6\u7684\u9ad8\u5ea6\u4f9d\u8cf4\u6027\u4fc3\u9032\u4e86\u5316\u7642\u6216\u653e\u5c04\u640d\u50b7\u5f8c\u7684\u80fd\u91cf\u5bc6\u96c6\u9632\u79a6\u548c\u4fee\u5fa9\u6a5f\u5236\u3002<\/li>\n<li>\u5c0d\u9ea9\u91af\u80fa\u9178\u4ee3\u8b1d\u7684\u65e5\u76ca\u4f9d\u8cf4\u4f7f\u50b3\u7d71\u6cbb\u7642\u6548\u679c\u9032\u4e00\u6b65\u8907\u96dc\u5316\uff0c\u5728\u50b3\u7d71\u7642\u6cd5\u5178\u578b\u7684\u71df\u990a\u9650\u5236\u689d\u4ef6\u4e0b\u7dad\u6301\u764c\u7d30\u80de\u7684\u5b58\u6d3b\u3002<\/li>\n<\/ul>\n<p>\u9451\u65bc ACC \u7684\u4ee3\u8b1d\u5f48\u6027\uff0c\u63a1\u7528\u76f4\u63a5\u91dd\u5c0d\u9019\u4e9b\u4ee3\u8b1d\u9069\u61c9\u7684\u6cbb\u7642\u7b56\u7565\u53ef\u80fd\u6703\u5927\u5927\u63d0\u9ad8\u6cbb\u7642\u6210\u529f\u7387\uff0c\u9019\u8aaa\u660e\u4e86\u5728\u81e8\u5e8a\u5be6\u8e10\u4e2d\u8f49\u5411\u57fa\u65bc\u4ee3\u8b1d\u7684\u5275\u65b0\u7642\u6cd5\u7684\u5fc5\u8981\u6027\u3002<\/p>\n<h3 id=\"addressing-the-treatment-gap-in-hong-kong-and-asia\">\u89e3\u6c7a\u9999\u6e2f\u548c\u4e9e\u6d32\u7684\u6cbb\u7642\u5dee\u8ddd<\/h3>\n<p>\u4e9e\u6d32\u4eba\u53e3\uff0c\u5c24\u5176\u662f\u9999\u6e2f\u4eba\u53e3\uff0c\u817a\u6a23\u56ca\u6027\u764c\u7684\u767c\u751f\u7387\u6b63\u5728\u4e0a\u5347\u3002\u50b3\u7d71\u764c\u75c7\u6cbb\u7642\u7684\u6b21\u4f73\u7642\u6548\u548c\u56b4\u91cd\u6bd2\u6027\u7d66\u91ab\u7642\u4fdd\u5065\u5c08\u696d\u4eba\u54e1\u548c\u60a3\u8005\u5e36\u4f86\u4e86\u6311\u6230\uff1a<\/p>\n<ul>\n<li>\u5728\u4eba\u53e3\u7a20\u5bc6\u3001\u8cc7\u6e90\u7dca\u5f35\u7684\u91ab\u7642\u57fa\u790e\u8a2d\u65bd\u4e2d\uff0c\u6cbb\u7642\u5ef6\u8aa4\u6703\u986f\u8457\u589e\u52a0\u764c\u75c7\u4f75\u767c\u75c7\u7684\u98a8\u96aa\u3002<\/li>\n<li>\u5148\u9032\u7684\u91dd\u5c0d\u6027\u5e79\u9810\u63aa\u65bd\u7684\u53ef\u7528\u6027\u6709\u9650\uff0c\u5c0e\u81f4\u5c0d\u50b3\u7d71\u65b9\u6cd5\u7684\u4f9d\u8cf4\uff0c\u7e7c\u767c\u6027\u4f75\u767c\u75c7\u8f03\u9ad8\uff0c\u5c0d\u81e8\u5e8a\u7d50\u679c\u7522\u751f\u4e0d\u5229\u5f71\u97ff\u3002<\/li>\n<li>\u5927\u773e\u5c0d\u6cbb\u7642\u65b9\u6848\u7684\u8a8d\u8b58\u4e0d\u8db3\uff0c\u9032\u4e00\u6b65\u52a0\u5287\u4e86\u53ca\u6642\u7372\u5f97\u5148\u9032\u3001\u66f4\u6709\u6548\u7684\u6cbb\u7642\u65b9\u6848\u7684\u56f0\u96e3\u3002<\/li>\n<\/ul>\n<p>\u56e0\u6b64\uff0c\u7e2e\u5c0f\u666e\u904d\u5b58\u5728\u7684\u6cbb\u7642\u5dee\u8ddd\u9700\u8981\u52a0\u901f\u5be6\u65bd\u5275\u65b0\u7642\u6cd5\uff0c\u64f4\u5927\u60a3\u8005\u7684\u53ef\u53ca\u6027\u548c\u7d9c\u5408 ACC \u6cbb\u7642\u7b56\u7565\u7684\u6709\u6548\u6027\u3002<\/p>\n<h3 id=\"conclusion-moving-towards-next-generation-therapies-in-adenoid-cystic-carcinoma-\">\u7d50\u8ad6\uff1a\u817a\u6a23\u56ca\u6027\u764c (ACC) \u9081\u5411\u4e0b\u4e00\u4ee3\u6cbb\u7642<\/h3>\n<p>\u5316\u7642\u3001\u653e\u7642\u548c\u624b\u8853\u65b9\u6cd5\u7684\u660e\u986f\u9650\u5236\u51f8\u986f\u4e86\u817a\u6a23\u56ca\u6027\u764c\u7684\u5de8\u5927\u6cbb\u7642\u5dee\u8ddd\u3002\u89e3\u6c7a\u56fa\u6709\u7684\u6cbb\u7642\u6297\u85e5\u6027\u3001\u56b4\u91cd\u7684\u526f\u4f5c\u7528\u548c\u8cc7\u6e90\u5bc6\u96c6\u578b\u9700\u6c42\u5f37\u8abf\u8feb\u5207\u9700\u8981\u958b\u62d3\u5275\u65b0\u7684\u6cbb\u7642\u65b9\u6cd5\u3002<\/p>\n<p>\u57fa\u65bc\u4ee3\u8b1d\u7684\u6a19\u9776\u6cbb\u7642\u6709\u671b\u5be6\u73fe\u66f4\u9ad8\u7684\u7279\u7570\u6027\uff0c\u6e1b\u5c11\u56b4\u91cd\u7684\u4e0d\u826f\u53cd\u61c9\uff0c\u4e26\u6709\u53ef\u80fd\u5c07 ACC \u8f49\u8b8a\u70ba\u66f4\u6613\u65bc\u63a7\u5236\u7684\u6162\u6027\u72c0\u614b\u3002\u900f\u904e\u5c07\u7814\u7a76\u6295\u8cc7\u548c\u81e8\u5e8a\u61c9\u7528\u96c6\u4e2d\u5728 ACC \u764c\u7d30\u80de\u56fa\u6709\u7684\u4ee3\u8b1d\u8106\u5f31\u6027\uff0c\u6211\u5011\u53ef\u4ee5\u8fce\u4f86\u4e00\u500b\u5145\u6eff\u5e0c\u671b\u7684\u672a\u4f86\u2014\u2014\u900f\u904e\u6df1\u5733\u524d\u6d77\u6cf0\u5eb7\u7b49\u7576\u5730\u5408\u4f5c\u5925\u4f34\u4ee5\u53ca\u8207 MD \u5b89\u5fb7\u68ee\u7684\u5168\u7403\u5408\u4f5c\u7684\u9032\u4e00\u6b65\u652f\u6301\u3002<\/p>\n<h2>\u56db\u7dad\u7121\u6bd2\u764c\u75c7\u7642\u6cd5\u6cbb\u7642\u65b9\u6cd5<\/h2>\n<p>\u9999\u6e2f\u4ee3\u8b1d\u816b\u7624\u6cbb\u7642\u4e2d\u5fc3\u63d0\u51fa\u7684\u56db\u7dad\u7121\u6bd2\u7642\u6cd5\u4ee3\u8868\u4e86\u4e00\u7a2e\u591a\u5c64\u9762\u7684\u764c\u75c7\u6cbb\u7642\u65b9\u6cd5\uff0c\u65e8\u5728\u5c07\u764c\u75c7\u8f49\u8b8a\u70ba\u53ef\u63a7\u5236\u7684\u6162\u6027\u75be\u75c5\u3002\u672c\u8abf\u67e5\u5831\u544a\u57fa\u65bc\u6240\u63d0\u4f9b\u7684\u6587\u4ef6\uff0c\u4e26\u900f\u904e\u57fa\u65bc\u7db2\u8def\u7684\u79d1\u5b78\u6587\u737b\u7684\u5ee3\u6cdb\u7814\u7a76\u9032\u884c\u4e86\u88dc\u5145\uff0c\u5c0d\u56db\u7a2e\u65b9\u6cd5\uff08\u4ee3\u8b1d\u6291\u5236\u3001\u7bc0\u5f8b\u6027\u816b\u7624\u63a7\u5236\u3001\u57fa\u56e0\u9776\u5411\u65ac\u9996\u548c\u514d\u75ab\u98a8\u66b4\u6fc0\u6d3b\uff09\u9032\u884c\u4e86\u5168\u9762\u5206\u6790\u3002\u5206\u6790\u5305\u62ec\u79d1\u5b78\u539f\u7406\u3001\u81e8\u5e8a\u8b49\u64da\u548c\u6f5b\u5728\u6311\u6230\uff0c\u6700\u7d42\u63d0\u51fa\u4e86\u53e3\u865f\u548c\u53e3\u865f\u3002<\/p>\n<h3>\u4ee3\u8b1d\u6291\u5236<\/h3>\n<p><strong>\u7e3d\u7d50\u8207\u6a5f\u5236<\/strong>\uff1a\u9019\u7a2e\u65b9\u6cd5\u91dd\u5c0d\u764c\u7d30\u80de\u7684\u4ee3\u8b1d\u8106\u5f31\u6027\uff0c\u7279\u5225\u662f\u5b83\u5011\u5c0d\u8461\u8404\u7cd6\u3001\u9ea9\u91af\u80fa\u9178\u548c\u8102\u8cea\u5408\u6210\u7684\u4f9d\u8cf4\u3002\u5b83\u4f7f\u7528\u8af8\u5982\u7528\u65bc\u8461\u8404\u7cd6\u8f49\u904b\u7684 GLUT1\/3\u3001\u7528\u65bc\u8c37\u6c28\u9170\u80fa\u4ee3\u8b1d\u7684 GLS\/ASCT2 \u4ee5\u53ca\u7528\u65bc\u8102\u8cea\u5408\u6210\u7684 FASN \u7b49\u6291\u5236\u5291\uff0c\u901a\u5e38\u900f\u904e\u5948\u7c73\u8f09\u9ad4\u905e\u9001\u3002\u4eba\u5de5\u667a\u6167\u9a45\u52d5\u7684\u71df\u990a\u8abf\u7bc0\u63d0\u9ad8\u4e86\u7cbe\u78ba\u5ea6\uff0c\u65e8\u5728\u5f15\u767c ATP \u5371\u6a5f\u4e26\u524a\u5f31\u764c\u7d30\u80de\u3002\u6587\u4ef6\u8072\u7a31\u816b\u7624\u8461\u8404\u7cd6\u651d\u53d6\u6e1b\u5c11\u4e86 82%\uff0c\u8840\u6f3f\u9ea9\u91af\u80fa\u9178\u6e1b\u5c11\u4e86 79%\uff0c\u819c\u78f7\u8102\u5408\u6210\u6e1b\u5c11\u4e86 91%\u3002<\/p>\n<p><strong>\u79d1\u5b78\u4f9d\u64da<\/strong>\uff1a\u7814\u7a76\uff0c\u4f8b\u5982 <a href=\"https:\/\/www.nature.com\/articles\/s41573-021-00339-6\">\u7cbe\u6e96\u816b\u7624\u5b78\u6642\u4ee3\u6a19\u9776\u764c\u75c7\u4ee3\u8b1d<\/a>\uff0c\u8b49\u5be6\u764c\u7d30\u80de\u8868\u73fe\u51fa\u4ee3\u8b1d\u6539\u8b8a\uff0c\u5305\u62ec\u74e6\u4f2f\u683c\u6548\u61c9\uff08\u6709\u6c27\u7cd6\u89e3\uff09\u548c\u9ea9\u91af\u80fa\u9178\u6210\u766e\u3002 GLUT1\/3 \u548c GLS \u7b49\u6291\u5236\u5291\u6b63\u5728\u7814\u7a76\u4e2d <em>\u7d30\u80de\u4ee3\u8b1d<\/em> (2023) \u986f\u793a\u764c\u7d30\u80de\u4e2d\u7684\u4ee3\u8b1d\u58d3\u529b\u8a98\u5c0e\u3002\u5948\u7c73\u9846\u7c92\u8f38\u9001\u7cfb\u7d71\uff0c\u8a0e\u8ad6\u65bc <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2590183420300028\">\u764c\u75c7\u6cbb\u7642\u4e2d\u57fa\u65bc\u5948\u7c73\u9846\u7c92\u7684\u85e5\u7269\u8f38\u9001<\/a>\uff0c\u589e\u5f37\u7279\u7570\u6027\uff0c\u5118\u7ba1\u816b\u7624\u7570\u8cea\u6027\u548c\u812b\u9776\u6548\u61c9\u7b49\u6311\u6230\u4ecd\u7136\u5b58\u5728\u3002<\/p>\n<p><strong>\u81e8\u5e8a\u8b49\u64da\u8207\u6311\u6230<\/strong>\uff1a\u6240\u8072\u7a31\u7684\u81e8\u5e8a\u76ca\u8655\u8207\u65b0\u8208\u8a66\u9a57\u4e00\u81f4\uff0c\u4f46\u764c\u75c7\u985e\u578b\uff08\u4f8b\u5982\u80ba\u764c\u8207\u4e73\u764c\uff09\u548c\u60a3\u8005\u53cd\u61c9\u7684\u5dee\u7570\u8868\u660e\u9700\u8981\u500b\u6027\u5316\u7684\u65b9\u6cd5\u3002 2024\u5e74 <em>\u7d30\u80de<\/em> \u6587\u4ef6\u4e2d\u5f15\u7528\u7684\u7814\u7a76\u8072\u7a31\u6297\u85e5\u6027\u57fa\u56e0\u8868\u73fe\u6e1b\u5c11\u4e86 80%\uff0c\u9700\u8981\u900f\u904e\u66f4\u5927\u898f\u6a21\u7684\u591a\u4e2d\u5fc3\u8a66\u9a57\u9032\u884c\u9a57\u8b49\u3002\u502b\u7406\u65b9\u9762\u7684\u8003\u616e\uff0c\u4f8b\u5982\u7372\u53d6\u548c\u8ca0\u64d4\u80fd\u529b\uff0c\u5728 <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2949723X23000533\">\u57fa\u65bc\u5948\u7c73\u9846\u7c92\u7684\u85e5\u7269\u50b3\u8f38\u7cfb\u7d71\u7684\u529f\u6548\u56de\u9867<\/a>.<\/p>\n<h3>\u7bc0\u5f8b\u6027\u816b\u7624\u63a7\u5236<\/h3>\n<p><strong>\u7e3d\u7d50\u8207\u6a5f\u5236<\/strong>\uff1a\u6b64\u65b9\u6cd5\u4f7f\u7528\u4f4e\u5291\u91cf\u3001\u7bc0\u5f8b\u5316\u7642\uff08\u50b3\u7d71\u5291\u91cf\u7684 1\/10\uff09\u548c\u8840\u7ba1\u6b63\u5e38\u5316\u56e0\u5b50\u4f86\u63a7\u5236\u816b\u7624\u751f\u9577\uff0c\u964d\u4f4e\u6bd2\u6027\u4e26\u5be6\u73fe 67% \u7684\u5bb6\u5ead\u6cbb\u7642\u3002\u64da\u8072\u7a31\uff0c\u5b83\u5c07\u7121\u60e1\u5316\u5b58\u6d3b\u671f\u5f9e 5.2 \u500b\u6708\u5ef6\u9577\u81f3 11.8 \u500b\u6708\uff0c\u4e26\u5c07\u56b4\u91cd\u6bd2\u6027\u964d\u4f4e 67%\u3002<\/p>\n<p><strong>\u79d1\u5b78\u4f9d\u64da<\/strong>\uff1a\u4f4e\u5291\u91cf\u7bc0\u5f8b\u5316\u7642\u5df2\u88ab\u5ee3\u6cdb\u63a5\u53d7\uff0c\u5982 <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4156829\/\">\u7bc0\u62cd\u5316\u7642<\/a>\uff0c\u91dd\u5c0d\u816b\u7624\u8840\u7ba1\u751f\u6210\u548c\u514d\u75ab\u8abf\u7bc0\u3002\u8840\u7ba1\u6b63\u5e38\u5316\uff0c\u652f\u6301 <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2405844024007011\">\u7bc0\u62cd\u5316\u7642\u548c\u85e5\u7269\u518d\u5229\u7528<\/a>\uff0c\u900f\u904e\u589e\u5f37\u8840\u7ba1\u529f\u80fd\u4f86\u6539\u5584\u85e5\u7269\u8f38\u9001\u3002\u7814\u7a76\u5982 <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0959804913005418\">\u4f4e\u5291\u91cf\u7bc0\u62cd\u5316\u7642\uff1a\u7cfb\u7d71\u6027\u6587\u737b\u5206\u6790<\/a> \u78ba\u8a8d\u6e1b\u5c11\u7684\u526f\u4f5c\u7528\u548c\u6f5b\u5728\u7684\u6210\u672c\u6548\u76ca\uff0c\u7279\u5225\u662f\u5728\u4f4e\u6536\u5165\u74b0\u5883\u4e2d\u3002<\/p>\n<p><strong>\u81e8\u5e8a\u8b49\u64da\u8207\u6311\u6230<\/strong>\uff1a\u8072\u7a31\u7684\u76ca\u8655\u8207\u8f49\u79fb\u6027\u4e73\u764c\u7684\u81e8\u5e8a\u6578\u64da\u4e00\u81f4\uff0c\u4f46\u7642\u6548\u53ef\u80fd\u56e0\u816b\u7624\u985e\u578b\u548c\u60a3\u8005\u5065\u5eb7\u72c0\u6cc1\u800c\u7570\u3002\u5bb6\u5ead\u6cbb\u7642\u6a21\u5f0f\u96d6\u7136\u6709\u5e0c\u671b\uff0c\u4f46\u9700\u8981\u5805\u6301\u548c\u76e3\u6e2c\uff0c\u5982 <a href=\"https:\/\/www.lifespringcancercenter.com\/our-treatment\/low-dose-metronomic-chemotherapy\">\u751f\u547d\u6cc9\u764c\u75c7\u6cbb\u7642\u4e2d\u5fc3<\/a>\u3002\u95dc\u65bc\u6297\u85e5\u6027\u548c\u751f\u6d3b\u54c1\u8cea\u7684\u9577\u671f\u6578\u64da\u9700\u8981\u9032\u4e00\u6b65\u63a2\u7d22\u3002<\/p>\n<h3>\u57fa\u56e0\u6a19\u9776\u65ac\u9996<\/h3>\n<p><strong>\u7e3d\u7d50\u8207\u6a5f\u5236<\/strong>\uff1a\u6b64\u65b9\u6cd5\u4f7f\u7528\u6db2\u9ad4\u6d3b\u6aa2\u4f86\u6aa2\u6e2c 487 \u500b\u764c\u75c7\u9a45\u52d5\u57fa\u56e0\uff0c\u4e26\u4f7f\u7528\u5948\u7c73\u9846\u7c92\u905e\u9001\u7cfb\u7d71\u4f86\u9776\u5411 KRAS\u3001BRAF \u548c TP53 \u7b49\u7a81\u8b8a\uff0c\u5f9e\u800c\u514b\u670d\u8840\u8166\u5c4f\u969c\u7b49\u969c\u7919\u3002\u5b83\u8072\u7a31 ORR \u63d0\u9ad8\u4e86 67%\uff0c\u905e\u9001\u6548\u7387\u63d0\u9ad8\u4e86 9 \u500d\uff0c\u7279\u5225\u662f\u5c0d\u65bc\u8f49\u79fb\u7624\u3002<\/p>\n<p><strong>\u79d1\u5b78\u4f9d\u64da<\/strong>\uff1a\u5948\u7c73\u9846\u7c92\u8f38\u9001\u662f\u4e00\u500b\u524d\u6cbf\u9818\u57df\uff0c <a href=\"https:\/\/www.cancer.gov\/nano\/cancer-nanotechnology\/treatment\">\u5948\u7c73\u6280\u8853\u764c\u75c7\u6cbb\u7642\u548c\u6cbb\u7642<\/a> \u5f37\u8abf\u5176\u7a7f\u900f\u751f\u7406\u5c4f\u969c\u7684\u80fd\u529b\u3002\u6db2\u9ad4\u6d3b\u6aa2\uff0c\u8a0e\u8ad6\u65bc <a href=\"https:\/\/jnanobiotechnology.biomedcentral.com\/articles\/10.1186\/s12951-025-03433-8\">\u63a8\u9032\u764c\u75c7\u57fa\u56e0\u6cbb\u7642<\/a>\uff0c\u5be6\u73fe\u5373\u6642\u7a81\u8b8a\u6aa2\u6e2c\uff0c\u8207\u7cbe\u6e96\u816b\u7624\u5b78\u8da8\u52e2\u4fdd\u6301\u4e00\u81f4\u3002\u7814\u7a76\u65bc <a href=\"https:\/\/www.nature.com\/articles\/s41392-023-01642-x\">\u7528\u65bc\u764c\u75c7\u6cbb\u7642\u7684\u667a\u6167\u5948\u7c73\u9846\u7c92<\/a> \u5118\u7ba1\u6bd2\u6027\u548c\u9776\u5411\u7279\u7570\u6027\u7b49\u6311\u6230\u4ecd\u7136\u5b58\u5728\uff0c\u4f46\u5b83\u986f\u793a\u51fa\u6cbb\u7642\u8166\u8f49\u79fb\u7684\u5e0c\u671b\u3002<\/p>\n<p><strong>\u81e8\u5e8a\u8b49\u64da\u8207\u6311\u6230<\/strong>\uff1a\u8072\u7a31\u7684 ORR \u70ba 67% \u662f\u96c4\u5fc3\u52c3\u52c3\u7684\uff0c\u96d6\u7136\u65e9\u671f\u8a66\u9a57\u986f\u793a\u51fa\u5e0c\u671b\uff0c\u4f46\u9700\u8981\u66f4\u5927\u898f\u6a21\u7684\u7814\u7a76\u4f86\u9a57\u8b49\u8de8\u816b\u7624\u985e\u578b\u7684\u7642\u6548\u3002\u816b\u7624\u7570\u8cea\u6027\uff0c\u5982\u4e2d\u6240\u8ff0 <a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-023-01865-0\">\u9032\u6b65\u5948\u7c73\u6280\u8853\u4ee5\u6539\u5584\u6a19\u9776\u764c\u75c7\u6cbb\u7642<\/a>\uff0c\u53ef\u80fd\u6703\u9650\u88fd\u6210\u529f\uff0c\u9700\u8981\u7d44\u5408\u7b56\u7565\u3002<\/p>\n<h3>\u514d\u75ab\u98a8\u66b4\u6fc0\u6d3b<\/h3>\n<p><strong>\u7e3d\u7d50\u8207\u6a5f\u5236<\/strong>\uff1a\u6b64\u65b9\u6cd5\u4f7f\u7528 PD-1\/CTLA-4 \u6291\u5236\u5291\u3001\u65b0\u6297\u539f\u75ab\u82d7\u3001CAR-NK \u7d30\u80de\u548c\u5fae\u751f\u7269\u7d44\u8abf\u7bc0\u4f86\u6d3b\u5316\u591a\u5c64\u514d\u75ab\u53cd\u61c9\u3002\u5b83\u8072\u7a31 3 \u5e74\u5b58\u6d3b\u7387\u70ba 62.7%\uff08\u6539\u5584\u4e86 244%\uff09\uff0c\u5fa9\u767c\u7387\u964d\u4f4e\u4e86 85%\uff0c\u5c07\u300c\u51b7\u300d\u816b\u7624\u8f49\u8b8a\u70ba\u300c\u71b1\u300d\u816b\u7624\u3002<\/p>\n<p><strong>\u79d1\u5b78\u4f9d\u64da<\/strong>\uff1a\u806f\u5408\u514d\u75ab\u7642\u6cd5\u662f\u9818\u5148\u9818\u57df\uff0c <a href=\"https:\/\/jhoonline.biomedcentral.com\/articles\/10.1186\/s13045-021-01164-5\">\u6700\u5927\u5316\u764c\u75c7\u514d\u75ab\u6cbb\u7642\u76ca\u8655\u7684\u7d44\u5408\u7b56\u7565<\/a> \u986f\u793a\u51fa\u589e\u5f37\u7684\u53cd\u61c9\u3002\u6aa2\u67e5\u9ede\u6291\u5236\u5291\u3001\u65b0\u6297\u539f\u75ab\u82d7\u548c CAR-T\/NK \u7642\u6cd5\uff0c\u53c3\u898b <a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-025-02305-x\">\u764c\u75c7\u514d\u75ab\u6cbb\u7642\u7684\u9032\u5c55<\/a>\u3001\u63d0\u9ad8\u514d\u75ab\u8fa8\u8b58\u80fd\u529b\u3002\u5fae\u751f\u7269\u7d44\u8abf\u7bc0\uff0c\u7a81\u51fa\u986f\u793a\u65bc <a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-021-01316-8\">\u764c\u75c7\u4ee3\u8b1d\u91cd\u7de8\u7a0b\u548c\u514d\u75ab\u53cd\u61c9<\/a>\uff0c\u5f71\u97ff\u514d\u75ab\u6cbb\u7642\u7684\u7d50\u679c\uff0c\u5118\u7ba1\u5176\u4e00\u81f4\u6027\u6709\u722d\u8b70\u3002<\/p>\n<p><strong>\u81e8\u5e8a\u8b49\u64da\u8207\u6311\u6230<\/strong>\uff1a\u8072\u7a31\u7684\u751f\u5b58\u7387\u8207\u6700\u8fd1\u7684\u8a66\u9a57\u4e00\u81f4\uff0c\u4f46\u5be6\u9ad4\u7624\u7531\u65bc\u7570\u8cea\u6027\u548c\u514d\u75ab\u6291\u5236\u5fae\u74b0\u5883\u800c\u5e36\u4f86\u6311\u6230\uff0c\u5982 <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2772906024004989\">\u764c\u75c7\u514d\u75ab\u7642\u6cd5\u7684\u6700\u65b0\u9032\u5c55<\/a>\u3002\u95dc\u65bc\u5fa9\u767c\u548c\u514d\u75ab\u8a18\u61b6\u7684\u9577\u671f\u6578\u64da\u9700\u8981\u9032\u4e00\u6b65\u9a57\u8b49\u3002<\/p>\n<h3>\u6bd4\u8f03\u81e8\u5e8a\u7d50\u679c<\/h3>\n<p>\u9019\u4e9b\u6587\u4ef6\u63d0\u4f9b\u4e86\u4e00\u500b\u6bd4\u8f03\u50b3\u7d71\u7642\u6cd5\u548c\u56db\u7dad\u7642\u6cd5\u7684\u8868\u683c\uff0c\u70ba\u6e05\u695a\u8d77\u898b\uff0c\u5c07\u5176\u8907\u88fd\u5982\u4e0b\uff1a<\/p>\n<figure>\n<table class=\"has-fixed-layout\">\n<tbody>\n<tr>\n<td>\u6307\u6a19<\/td>\n<td>\u50b3\u7d71\u7684<br \/>\u6cbb\u7642<\/td>\n<td>\u56db\u7dad<br \/>\u6cbb\u7642<\/td>\n<td>\u6539\u9032<\/td>\n<\/tr>\n<tr>\n<td>\u5ba2\u89c0\u7de9\u89e3\u7387 (ORR)<\/td>\n<td>31%<\/td>\n<td>67%<\/td>\n<td>\u2191116%<\/td>\n<\/tr>\n<tr>\n<td>3 \u5e74\u5b58\u6d3b\u7387<\/td>\n<td>18%<\/td>\n<td>62.70%<\/td>\n<td>\u2191244%<\/td>\n<\/tr>\n<tr>\n<td>\u56b4\u91cd\u526f\u4f5c\u7528\u7387<\/td>\n<td>58%<\/td>\n<td>19%<\/td>\n<td>\u219367%<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/figure>\n<p>\u8868\u683c\u5f37\u8abf\u4e86\u8a72\u7642\u6cd5\u7684\u6f5b\u529b\uff0c\u4f46\u60a3\u8005\u7fa4\u9ad4\u548c\u816b\u7624\u985e\u578b\u4e4b\u9593\u7684\u5dee\u7570\u503c\u5f97\u9032\u4e00\u6b65\u7814\u7a76\u3002<\/p>\n<h2><strong>\u7d50\u8ad6<\/strong><\/h2>\n<p>\u56db\u7dad\u7121\u6bd2\u7642\u6cd5\u6574\u5408\u4e86\u89e3\u6c7a\u764c\u75c7\u8907\u96dc\u6027\u7684\u5c16\u7aef\u7b56\u7565\uff0c\u6bcf\u7a2e\u65b9\u6cd5\u90fd\u5f97\u5230\u65b0\u8208\u7814\u7a76\u7684\u652f\u6301\u3002\u7136\u800c\uff0c\u816b\u7624\u7570\u8cea\u6027\u3001\u81e8\u5e8a\u9a57\u8b49\u548c\u53ef\u8fd1\u6027\u7b49\u6311\u6230\u9700\u8981\u4e0d\u65b7\u63a2\u7d22\u3002\u5efa\u8b70\u7684\u53e3\u865f\u548c\u53e3\u865f\u65e8\u5728\u9ad4\u73fe\u8a72\u7642\u6cd5\u7684\u627f\u8afe\uff0c\u4e26\u5f15\u767c\u5c0d\u5176\u6539\u8b8a\u764c\u75c7\u6cbb\u7642\u6f5b\u529b\u7684\u9032\u4e00\u6b65\u8a0e\u8ad6\u3002<\/p>\n<h2>\u4e3b\u8981\u5f15\u6587<\/h2>\n<ul>\n<li><a href=\"https:\/\/www.nature.com\/articles\/s41573-021-00339-6\">\u7cbe\u6e96\u816b\u7624\u5b78\u6642\u4ee3\u6a19\u9776\u764c\u75c7\u4ee3\u8b1d<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2590183420300028\">\u764c\u75c7\u6cbb\u7642\u4e2d\u57fa\u65bc\u5948\u7c73\u9846\u7c92\u7684\u85e5\u7269\u8f38\u9001<\/a><\/li>\n<li><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4156829\/\">\u7bc0\u62cd\u5316\u7642<\/a><\/li>\n<li><a href=\"https:\/\/jnanobiotechnology.biomedcentral.com\/articles\/10.1186\/s12951-025-03433-8\">\u63a8\u9032\u764c\u75c7\u57fa\u56e0\u6cbb\u7642<\/a><\/li>\n<li><a href=\"https:\/\/jhoonline.biomedcentral.com\/articles\/10.1186\/s13045-021-01164-5\">\u6700\u5927\u5316\u764c\u75c7\u514d\u75ab\u6cbb\u7642\u76ca\u8655\u7684\u7d44\u5408\u7b56\u7565<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2772906024004989\">\u764c\u75c7\u514d\u75ab\u7642\u6cd5\u7684\u6700\u65b0\u9032\u5c55<\/a><\/li>\n<li><a href=\"https:\/\/www.cancer.gov\/nano\/cancer-nanotechnology\/treatment\">\u5948\u7c73\u6280\u8853\u764c\u75c7\u6cbb\u7642\u548c\u6cbb\u7642<\/a><\/li>\n<li><a href=\"https:\/\/www.nature.com\/articles\/s41392-023-01642-x\">\u7528\u65bc\u764c\u75c7\u6cbb\u7642\u7684\u667a\u6167\u5948\u7c73\u9846\u7c92<\/a><\/li>\n<li><a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-021-01316-8\">\u764c\u75c7\u4ee3\u8b1d\u91cd\u7de8\u7a0b\u548c\u514d\u75ab\u53cd\u61c9<\/a><\/li>\n<li><a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-025-02305-x\">\u764c\u75c7\u514d\u75ab\u6cbb\u7642\u7684\u9032\u5c55<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2405844024007011\">\u7bc0\u62cd\u5316\u7642\u548c\u85e5\u7269\u518d\u5229\u7528<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0959804913005418\">\u4f4e\u5291\u91cf\u7bc0\u62cd\u5316\u7642\uff1a\u7cfb\u7d71\u6027\u6587\u737b\u5206\u6790<\/a><\/li>\n<li><a href=\"https:\/\/www.lifespringcancer.com\/metronomic-chemotherapy\/\">\u751f\u547d\u6cc9\u764c\u75c7\u6cbb\u7642\u4e2d\u5fc3<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2772906024004989\">\u57fa\u65bc\u5948\u7c73\u9846\u7c92\u7684\u85e5\u7269\u50b3\u8f38\u7cfb\u7d71\u7684\u529f\u6548\u56de\u9867<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2772906024004989\">\u9032\u6b65\u5948\u7c73\u6280\u8853\u4ee5\u6539\u5584\u6a19\u9776\u764c\u75c7\u6cbb\u7642<\/a><\/li>\n<\/ul>\n<hr>\n<div class=\"ac-blog-cta\">\n<h2>\u9700\u8981\u5354\u52a9\u4e86\u89e3\u6cbb\u7642\u9078\u64c7\uff1f<\/h2>\n<p>\u6211\u5011\u7684\u60a3\u8005\u670d\u52d9\u5718\u968a\u53ef\u4ee5\u5e6b\u52a9\u60a8\u6e96\u5099\u5831\u544a\u4e26\u5b89\u6392\u9069\u7576\u7684\u5c08\u5bb6\u8aee\u8a62\u3002\u672c\u6587\u662f\u4e00\u822c\u8a0a\u606f\uff0c\u800c\u4e0d\u662f\u8a3a\u65b7\u3002<\/p>\n<p><a href=\"\/zh-hk\/appointment\/\">\u9810\u7d04\u8aee\u8a62<\/a> &nbsp;|&nbsp; <a href=\"\/zh-hk\/cancer\/\">\u63a2\u7d22\u6240\u6709\u764c\u75c7\u985e\u578b<\/a><\/p>\n<\/div>\n<p class=\"ac-blog-disclaimer\"><em>\u91ab\u7642\u514d\u8cac\u8072\u660e\uff1a\u672c\u6587\u50c5\u7528\u65bc\u4e00\u822c\u6559\u80b2\uff0c\u4e0d\u80fd\u53d6\u4ee3\u5408\u683c\u81e8\u5e8a\u91ab\u751f\u7684\u5efa\u8b70\u3002\u6cbb\u7642\u6c7a\u5b9a\u61c9\u57fa\u65bc\u500b\u4eba\u7684\u8a3a\u65b7\u3001\u5206\u671f\u3001\u75c5\u7406\u548c\u6574\u9ad4\u5065\u5eb7\u72c0\u6cc1\u3002\u5982\u679c\u60a8\u767c\u73fe\u6301\u7e8c\u6216\u4ee4\u4eba\u64d4\u6182\u7684\u75c7\u72c0\uff0c\u8acb\u5c0b\u6c42\u91ab\u7642\u8a55\u4f30\u3002<\/em><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Adenoid Cystic Carcinoma (ACC) is an uncommon yet aggressive type of cancer that usually arises in glandular tissues, particularly affecting salivary glands.<\/p>","protected":false},"featured_media":256,"menu_order":51,"template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center 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