{"id":390,"date":"2026-06-06T09:00:00","date_gmt":"2026-06-06T09:00:00","guid":{"rendered":"https:\/\/all-cancers.com\/cancer\/non-small-cell-lung-cancer-nsclc-cancer\/"},"modified":"2026-10-29T13:38:07","modified_gmt":"2026-10-29T13:38:07","slug":"non-small-cell-lung-cancer-nsclc-cancer","status":"publish","type":"cancer_type","link":"https:\/\/all-cancers.com\/zh-hk\/cancer\/non-small-cell-lung-cancer-nsclc-cancer\/","title":{"rendered":"\u975e\u5c0f\u7d30\u80de\u80ba\u764c (NSCLC)"},"content":{"rendered":"<div class=\"ac-blog-article\">\n<p class=\"ac-blog-lead\"><strong>\u975e\u5c0f\u7d30\u80de\u80ba\u764c (NSCLC) \u7d04\u4f54\u6240\u6709\u80ba\u764c\u7684 85%\uff0c\u6bcf\u5e74\u5c0d\u5168\u7403\u6578\u767e\u842c\u4eba\u7522\u751f\u6df1\u9060\u5f71\u97ff\u3002\u4e86\u89e3\u975e\u5c0f\u7d30\u80de\u80ba\u764c (NSCLC) \u9996\u5148\u8981\u8a8d\u8b58\u5230\u5b83\u662f\u8d77\u6e90\u65bc\u80ba\u4e0a\u76ae\u7d30\u80de\u7684\u591a\u7a2e\u764c\u75c7\u3002\u6b64\u5206\u985e\u5305\u62ec\u817a\u764c\u3001\u9c57\u72c0\u7d30\u80de\u764c\u548c\u5927\u7d30\u80de\u764c\uff0c\u6bcf\u7a2e\u764c\u75c7\u90fd\u6709\u4e0d\u540c\u7684\u751f\u7269\u5b78\u7279\u5fb5\u548c\u884c\u70ba\u3002<\/strong><\/p>\n<nav class=\"ac-blog-toc\" aria-label=\"\u672c\u6587\u5c0e\u89bd\">\n<p><strong>\u672c\u6587\u5c0e\u89bd<\/strong><\/p>\n<ul>\n<li><a href=\"#what-is-non-small-cell-lung-cancer-nsclc\">\u4ec0\u9ebc\u662f\u975e\u5c0f\u7d30\u80de\u80ba\u764c (NSCLC)\uff1f<\/a><\/li>\n<li><a href=\"#causes-and-risk-factors-of-non-small-cell-lung-cancer-nsclc\">\u975e\u5c0f\u7d30\u80de\u80ba\u764c (NSCLC) \u7684\u75c5\u56e0\u548c\u5371\u96aa\u56e0\u5b50<\/a><\/li>\n<li><a href=\"#discover-revolutionary-4d-metabolic-therapy\">\u63a2\u7d22\u9769\u547d\u6027\u7684 4D \u4ee3\u8b1d\u7642\u6cd5<\/a><\/li>\n<li><a href=\"#symptoms-of-non-small-cell-lung-cancer-nsclc\">\u975e\u5c0f\u7d30\u80de\u80ba\u764c (NSCLC) \u7684\u75c7\u72c0<\/a><\/li>\n<li><a href=\"#stages-of-non-small-cell-lung-cancer-nsclc-and-survival-rates\">\u975e\u5c0f\u7d30\u80de\u80ba\u764c (NSCLC) \u7684\u5206\u671f\u548c\u5b58\u6d3b\u7387<\/a><\/li>\n<li><a href=\"#limitations-of-traditional-therapies-for-non-small-cell-lung-cancer-nsclc\">\u975e\u5c0f\u7d30\u80de\u80ba\u764c (NSCLC) \u50b3\u7d71\u7642\u6cd5\u7684\u5c40\u9650\u6027<\/a><\/li>\n<\/ul>\n<\/nav>\n<h2 id=\"what-is-non-small-cell-lung-cancer-nsclc\">\u4ec0\u9ebc\u662f <strong>\u975e\u5c0f\u7d30\u80de\u80ba\u764c (NSCLC)<\/strong>?<\/h2>\n<p>\u5728\u7d30\u80de\u5c64\u9762\u4e0a\uff0c\u975e\u5c0f\u7d30\u80de\u80ba\u764c\uff08NSCLC\uff09\u8868\u73fe\u51fa\u4e00\u7a2e\u986f\u8457\u7684\u4ee3\u8b1d\u7570\u5e38\uff0c\u7a31\u70ba <strong>\u74e6\u723e\u5821\u6548\u61c9<\/strong>\uff0c\u5176\u4e2d\u764c\u7d30\u80de\u8655\u7406\u8461\u8404\u7cd6\u7684\u901f\u5ea6\u5927\u7d04\u662f\u6b63\u5e38\u7d30\u80de\u7684 200 \u500d\u3002\u5373\u4f7f\u5728\u6c27\u6c23\u5145\u8db3\u7684\u60c5\u6cc1\u4e0b\uff0c\u9019\u7a2e\u5c0d\u6709\u6c27\u7cd6\u89e3\u7684\u504f\u597d\u4e5f\u6703\u4fc3\u9032\u764c\u75c7\u7684\u5feb\u901f\u589e\u6b96\uff0c\u4e26\u70ba\u5275\u65b0\u7642\u6cd5\u63d0\u4f9b\u4ee3\u8b1d\u76ee\u6a19\u3002<\/p>\n<p>\u6839\u64da\u4e16\u754c\u885b\u751f\u7d44\u7e54\uff08WHO\uff0c2024 \u5e74\u6578\u64da\uff09\uff0c\u76ee\u524d\u80ba\u764c\u6bcf\u5e74\u5f71\u97ff\u7d04 220 \u842c\u4eba\u3002\u5728\u9999\u6e2f\u548c\u4e9e\u6d32\u5404\u5730\uff0c\u80ba\u764c\u76db\u884c\u7387\u4ecd\u7136\u5f88\u9ad8\uff0c\u90e8\u5206\u539f\u56e0\u662f\u5730\u5340\u7279\u5b9a\u7684\u907a\u50b3\u56e0\u7d20\u3001\u74b0\u5883\u5f71\u97ff\u548c\u751f\u6d3b\u65b9\u5f0f\u6a21\u5f0f\u3002<\/p>\n<ul>\n<li>\u5728\u9999\u6e2f\uff0c\u80ba\u764c\u662f\u764c\u75c7\u76f8\u95dc\u6b7b\u4ea1\u7684\u4e3b\u8981\u539f\u56e0\uff0c\u7d04\u4f54\u764c\u75c7\u6b7b\u4ea1\u7387\u768427%\u3002<\/li>\n<li>\u7537\u6027\u7684\u76db\u884c\u7387\u7565\u9ad8\u65bc\u5973\u6027\uff0c\u4f46\u4e0d\u5438\u83f8\u5973\u6027\u7684\u75c5\u4f8b\u6b63\u5728\u4e0a\u5347\uff0c\u7279\u5225\u662f\u8207 EGFR \u7a81\u8b8a\u76f8\u95dc\u7684\u817a\u764c\u5728\u4e9e\u6d32\u4eba\u7fa4\u4e2d\u5360\u4e3b\u5c0e\u5730\u4f4d\u3002<\/li>\n<\/ul>\n<p>\u975e\u5c0f\u7d30\u80de\u80ba\u764c (NSCLC) \u60a3\u8005\u7684\u7d93\u6b77\u5f88\u8907\u96dc\uff0c\u5305\u62ec\u6301\u7e8c\u54b3\u55fd\u3001\u547c\u5438\u56f0\u96e3\u548c\u75b2\u52de\u7b49\u8eab\u9ad4\u75c7\u72c0\uff0c\u4ee5\u53ca\u7126\u616e\u3001\u6182\u9b31\u548c\u751f\u6d3b\u54c1\u8cea\u4e0b\u964d\u7b49\u60c5\u7dd2\u8ca0\u64d4\u3002\u5728\u764c\u75c7\u6cbb\u7642\u7684\u540c\u6642\u5168\u9762\u89e3\u6c7a\u9019\u4e9b\u554f\u984c\u81f3\u95dc\u91cd\u8981\u3002<\/p>\n<p>\u65e9\u671f\u767c\u73fe\u4ecd\u662f\u6539\u5584\u7d50\u679c\u7684\u57fa\u77f3\u3002\u9999\u6e2f\u7684\u80ba\u90e8\u7be9\u6aa2\u8a08\u756b\u7b49\u63aa\u65bd\u6709\u52a9\u65bc\u65e9\u671f\u767c\u73fe\uff0c\u4e26\u986f\u8457\u63d0\u9ad8\u5b58\u6d3b\u7387\u3002\u900f\u904e\u6211\u5011\u7684\u5275\u65b0\u767c\u73fe\u66f4\u591a\u6709\u95dc\u65e9\u671f\u8a3a\u65b7\u65b9\u6cd5\u7684\u4fe1\u606f <a href=\"\/zh-hk\/cancer\/\">\u65e9\u671f\u764c\u75c7\u6aa2\u6e2c\u8a08\u5283<\/a>.<\/p>\n<h3 id=\"biological-basis-of-non-small-cell-lung-cancer-nsclc\">\u975e\u5c0f\u7d30\u80de\u80ba\u764c (NSCLC) \u7684\u751f\u7269\u5b78\u57fa\u790e<\/h3>\n<p>\u5f9e\u751f\u7269\u5b78\u89d2\u5ea6\u4f86\u770b\uff0c\u7576\u80ba\u4e0a\u76ae\u7d30\u80de\u767c\u751f\u57fa\u56e0\u7a81\u8b8a\u4e26\u5c0e\u81f4\u4e0d\u53d7\u63a7\u5236\u7684\u589e\u751f\u6642\uff0c\u5c31\u6703\u767c\u751f\u975e\u5c0f\u7d30\u80de\u80ba\u764c\u3002\u6b63\u5e38\u7684\u7d30\u80de\u9031\u671f\u6aa2\u67e5\u9ede\u88ab\u7e5e\u904e\uff0c\u63a7\u5236\u7d30\u80de\u4ee3\u8b1d\u7684\u9014\u5f91\u88ab\u91cd\u65b0\u7de8\u7a0b\uff0c\u63d0\u4f9b\u5feb\u901f\u5206\u88c2\u6240\u9700\u7684\u80fd\u91cf\u548c\u7d50\u69cb\u6210\u5206\u3002\u827e\u5229\u68ee\u548c\u585e\u9580\u624e\u7b49\u8afe\u8c9d\u723e\u734e\u5f97\u4e3b\u7814\u7a76\u4eba\u54e1\u5f37\u8abf\u4e86\u764c\u7d30\u80de\u4ee3\u8b1d\u5728\u816b\u7624\u751f\u9577\u548c\u5b58\u6d3b\u4e2d\u767c\u63ee\u7684\u95dc\u9375\u4f5c\u7528\u3002<\/p>\n<h3 id=\"types-of-non-small-cell-lung-cancer-nsclc\">\u975e\u5c0f\u7d30\u80de\u80ba\u764c (NSCLC) \u7684\u985e\u578b<\/h3>\n<ul>\n<li><strong>\u817a\u764c<\/strong> \u2013 \u6700\u5e38\u898b\u7684\u985e\u578b\uff0c\u901a\u5e38\u51fa\u73fe\u5728\u80ba\u90e8\u7684\u5916\u90e8\u5340\u57df\uff0c\u8207\u4e0d\u5438\u7159\u8005\u6216\u4ee5\u524d\u5438\u7159\u8005\u5bc6\u5207\u76f8\u95dc\u3002<\/li>\n<li><strong>\u9c57\u72c0\u7d30\u80de\u764c<\/strong> \u2013 \u901a\u5e38\u4f4d\u65bc\u4e3b\u652f\u6c23\u7ba1\u4e2d\u592e\uff0c\u8207\u9577\u671f\u5438\u83f8\u5bc6\u5207\u76f8\u95dc\u3002<\/li>\n<li><strong>\u5927\u7d30\u80de\u764c<\/strong> \u2013 \u6700\u4e0d\u5e38\u898b\u7684\u5f62\u5f0f\uff0c\u8fc5\u901f\u50b3\u64ad\u4e26\u6355\u6349\u4ee3\u8b1d\u4f9d\u8cf4\u6027\u653b\u64ca\u6027\u3002<\/li>\n<\/ul>\n<h2 id=\"causes-and-risk-factors-of-non-small-cell-lung-cancer-nsclc\">\u975e\u5c0f\u7d30\u80de\u80ba\u764c (NSCLC) \u7684\u75c5\u56e0\u548c\u5371\u96aa\u56e0\u5b50<\/h2>\n<p>\u5c0e\u81f4 NSCLC \u7684\u98a8\u96aa\u56e0\u7d20\u6709\u591a\u7a2e\uff0c\u5305\u62ec\u907a\u50b3\u50be\u5411\u3001\u74b0\u5883\u66b4\u9732\u548c\u751f\u6d3b\u65b9\u5f0f\u9078\u64c7\u3002<\/p>\n<h3 id=\"genetic-factors\">\u907a\u50b3\u56e0\u7d20<\/h3>\n<p>\u4e86\u89e3\u907a\u50b3\u5b78\u5c0d\u65bc NSCLC \u75c5\u7406\u5b78\u81f3\u95dc\u91cd\u8981\uff1a<\/p>\n<ul>\n<li><strong>EGFR\u7a81\u8b8a<\/strong> \u2013 \u5728\u4e9e\u6d32\u975e\u5438\u83f8\u8005\u4e2d\u5c24\u5176\u666e\u904d\uff0c\u5c0e\u81f4\u51fa\u73fe\u916a\u80fa\u9178\u6fc0\u9176\u6291\u5236\u5291 (TKI) \u7b49\u6a19\u9776\u6cbb\u7642\u9078\u64c7\u3002<\/li>\n<li><strong>ALK \u91cd\u6392\u548c KRAS \u7a81\u8b8a<\/strong> \u2013 \u9810\u6e2c\u6cbb\u7642\u7d50\u679c\u548c\u9810\u5f8c\u7684\u986f\u8457\u907a\u50b3\u7570\u5e38\u3002<\/li>\n<\/ul>\n<h3 id=\"environmental-and-lifestyle-factors\">\u74b0\u5883\u548c\u751f\u6d3b\u65b9\u5f0f\u56e0\u7d20<\/h3>\n<ul>\n<li><strong>\u5438\u7159<\/strong> \u2013 \u4e3b\u8981\u539f\u56e0\uff0c\u4f54\u5168\u7403\u75c5\u4f8b\u7684 85% \u4ee5\u4e0a\uff0c\u4f46\u4e9e\u6d32 NSCLC \u75c5\u4f8b\u4e2d\u5f88\u5927\u4e00\u90e8\u5206\u51fa\u73fe\u5728\u975e\u5438\u7159\u8005\u4e2d\uff0c\u51f8\u986f\u4e86\u907a\u50b3\u6613\u611f\u6027\u3002<\/li>\n<li><strong>\u7a7a\u6c23\u6c61\u67d3<\/strong> \u2013 \u8fc5\u901f\u6210\u70ba\u4e00\u500b\u91cd\u8981\u7684\u5340\u57df\u8b70\u984c\uff0c\u7279\u5225\u662f\u5728\u9999\u6e2f\u3001\u5317\u4eac\u548c\u6771\u4eac\u7b49\u4eba\u53e3\u7a20\u5bc6\u7684\u4e9e\u6d32\u57ce\u5e02\u3002<\/li>\n<li><strong>\u8077\u696d\u66b4\u9732<\/strong> \u2013 \u7d93\u5e38\u63a5\u89f8\u77f3\u68c9\u3001\u6c21\u6c23\u3001\u77fd\u9178\u9e7d\u6216\u91cd\u91d1\u5c6c\u6703\u986f\u8457\u589e\u52a0\u975e\u5c0f\u7d30\u80de\u80ba\u764c\u7684\u98a8\u96aa\u3002<\/li>\n<li><strong>\u751f\u6d3b\u65b9\u5f0f\u7684\u7d44\u6210\u90e8\u5206<\/strong> \u2013 \u4e0d\u826f\u98f2\u98df\u3001\u4e45\u5750\u884c\u70ba\u548c\u6162\u6027\u767c\u708e\u6703\u5f71\u97ff\u80ba\u764c\u6613\u611f\u6027\u3002<\/li>\n<\/ul>\n<h3 id=\"metabolic-vulnerabilities-in-nsclc-cells\">NSCLC \u7d30\u80de\u7684\u4ee3\u8b1d\u8106\u5f31\u6027<\/h3>\n<p>\u5229\u7528\u4ee3\u8b1d\u4f9d\u8cf4\u6027\u662f NSCLC \u6cbb\u7642\u7684\u4e00\u9805\u5275\u65b0\u3002\u5728\u4ee3\u8b1d\u65b9\u9762\uff0c\u5927\u7d04 50% \u7684\u764c\u7d30\u80de\u986f\u8457\u4f9d\u8cf4\u9ea9\u91af\u80fa\u9178\u4f86\u5408\u6210\u6838\u82f7\u9178\u4e26\u652f\u6301\u5feb\u901f\u589e\u6b96\uff0c\u9019\u63d0\u4f9b\u4e86\u6f5b\u5728\u7684\u6cbb\u7642\u6a19\u9776\u6a5f\u6703\u3002<\/p>\n<h3 id=\"asian-specific-risks\">\u4e9e\u6d32\u7279\u6709\u7684\u98a8\u96aa<\/h3>\n<ul>\n<li>\u7279\u5225\u662f\uff0cEGFR \u967d\u6027\u817a\u764c\u5728\u6771\u4e9e\u4eba\u7fa4\u4e2d\u66f4\u70ba\u5e38\u898b\u3002<\/li>\n<li>\u4e9e\u6d32\u90e8\u5206\u5730\u5340\u76db\u884c\u7684\u7a7a\u6c23\u6c61\u67d3\u548c\u5ba4\u5167\u70f9\u98ea\u65b9\u6cd5\u8207\u80ba\u764c\u767c\u751f\u7387\u8f03\u9ad8\u6709\u95dc\u3002<\/li>\n<\/ul>\n<p>\u65e9\u671f\u8b58\u5225\uff0c\u4f8b\u5982 EGFR \u7a81\u8b8a\u7be9\u6aa2\uff0c\u900f\u904e\u500b\u4eba\u5316\u91ab\u7642\u986f\u8457\u63d0\u9ad8\u6cbb\u7642\u6548\u679c\u3002\u900f\u904e\u63a2\u7d22\u6211\u5011\u7684\u7d9c\u5408\u6027\u63aa\u65bd\uff0c\u9f13\u52f5\u7a4d\u6975\u4e3b\u52d5\u7684\u5065\u5eb7\u7ba1\u7406 <a href=\"\/zh-hk\/cancer\/\">\u764c\u75c7\u7be9\u6aa2\u8a08\u5283<\/a>.<\/p>\n<h2 id=\"discover-revolutionary-4d-metabolic-therapy\">\u63a2\u7d22\u9769\u547d\u6027\u7684 4D \u4ee3\u8b1d\u7642\u6cd5<\/h2>\n<p>\u50b3\u7d71\u7684NSCLC\u6cbb\u7642\u4e3b\u8981\u96c6\u4e2d\u5728\u5316\u7642\u3001\u624b\u8853\u3001\u653e\u7642\u548c\u6a19\u9776\u6cbb\u7642\u3002\u7136\u800c\uff0cAllCancer \u958b\u5275\u4e86\u5275\u65b0 <strong>4D\u4ee3\u8b1d\u7642\u6cd5<\/strong>\uff0c\u5229\u7528\u8afe\u8c9d\u723e\u734e\u5f97\u4e3b\u7684\u7814\u7a76\u6210\u679c\uff08Allison\u3001Semenza \u6559\u6388\u3001\u674e\u570b\u83ef\u535a\u58eb\u548c\u5289\u570b\u9f8d\u6559\u6388\uff09\u3002<\/p>\n<ul>\n<li>68.7% \u7684\u986f\u8457\u6574\u9ad4\u7de9\u89e3\u7387 (ORR) \u8aaa\u660e\u4e86\u8b8a\u9769\u6027\u7684\u6cbb\u7642\u6f5b\u529b\u3002<\/li>\n<li>\u7d04 80% \u7684\u8f49\u79fb\u6027\u7167\u8b77\u4ee5\u5bb6\u5ead\u70ba\u57fa\u790e\uff0c\u65e2\u65b9\u4fbf\u53c8\u63d0\u9ad8\u75c5\u60a3\u8212\u9069\u5ea6\u3002<\/li>\n<li>\u300c\u5148\u6cbb\u6108\uff0c\u5f8c\u4ed8\u8cbb\u300d\u7684\u653f\u7b56\uff0c\u9ad4\u73fe\u4e86\u8207\u6df1\u5733\u524d\u6d77\u6cf0\u5eb7\u3001MD\u5b89\u5fb7\u68ee\u7b49\u77e5\u540d\u6a5f\u69cb\u5408\u4f5c\u5c0d\u60a3\u8005\u81f3\u4e0a\u8b77\u7406\u7684\u5805\u5b9a\u627f\u8afe\u3002<\/li>\n<\/ul>\n<p>\u4e86\u89e3\u5982\u4f55\u5275\u65b0 <a href=\"\/zh-hk\/treatment-cancer\/\">4D\u6cbb\u7642<\/a> \u6539\u8b8a\u975e\u5c0f\u7d30\u80de\u80ba\u764c\uff08NSCLC\uff09\u6cbb\u7642\uff0c\u5e36\u4f86\u65b0\u7684\u5e0c\u671b\uff0c\u6539\u8b8a\u9810\u5f8c\uff0c\u4e26\u986f\u8457\u63d0\u9ad8\u751f\u6d3b\u54c1\u8cea\u3002<\/p>\n<p><em>\u60a3\u8005\u611f\u8a00\uff1a<\/em> \u300c\u611f\u8b1d AllCancer \u9769\u547d\u6027\u7684 4D \u7642\u6cd5\uff0c\u6211\u7684\u751f\u6d3b\u5f9e\u9eef\u6de1\u7684\u8a3a\u65b7\u8f49\u8b8a\u70ba\u7de9\u89e3\u548c\u5e0c\u671b\u3002<strong>\u2014 \u7d04\u7ff0\uff0c\u9999\u6e2f<\/strong><\/p>\n<h2 id=\"symptoms-of-non-small-cell-lung-cancer-nsclc\">\u975e\u5c0f\u7d30\u80de\u80ba\u764c (NSCLC) \u7684\u75c7\u72c0<\/h2>\n<p>\u8b58\u5225\u975e\u5c0f\u7d30\u80de\u80ba\u764c (NSCLC) \u7684\u65e9\u671f\u75c7\u72c0\u53ef\u4ee5\u986f\u8457\u6539\u5584\u9810\u5f8c\u3002\u75c7\u72c0\u53ef\u80fd\u56e0\u816b\u7624\u4f4d\u7f6e\u3001\u751f\u7269\u5b78\u7279\u5fb5\u548c\u9032\u5c55\u968e\u6bb5\u800c\u7570\u3002\u5c0d\u9019\u4e9b\u75c7\u72c0\u7684\u8a8d\u8b58\uff0c\u7279\u5225\u662f\u5728\u9999\u6e2f\u548c\u4e9e\u6d32\u5404\u5730\u80ba\u764c\u60a3\u75c5\u7387\u8f03\u9ad8\u7684\u5730\u5340\uff0c\u5c0d\u65bc\u53ca\u6642\u8a3a\u65b7\u548c\u6709\u6548\u6cbb\u7642\u81f3\u95dc\u91cd\u8981\u3002<\/p>\n<h3 id=\"common-nsclc-symptoms-include\">\u5e38\u898b\u7684\u975e\u5c0f\u7d30\u80de\u80ba\u764c\u75c7\u72c0\u5305\u62ec\uff1a<\/h3>\n<ul>\n<li>\u6301\u7e8c\u54b3\u55fd\u4e14\u52a0\u91cd\u6216\u7121\u6cd5\u7de9\u89e3<\/li>\n<li>\u54af\u8840\uff08\u54b3\u51fa\u8840\u6db2\u6216\u9435\u93fd\u8272\u75f0\uff09<\/li>\n<li>\u547c\u5438\u6025\u4fc3\u548c\u547c\u5438\u56f0\u96e3<\/li>\n<li>\u80f8\u75db\u96a8\u8457\u6df1\u547c\u5438\u6216\u54b3\u55fd\u800c\u52a0\u5287<\/li>\n<li>\u53cd\u8986\u547c\u5438\u9053\u611f\u67d3\uff0c\u5982\u652f\u6c23\u7ba1\u708e\u6216\u80ba\u708e<\/li>\n<li>\u75b2\u52de\u548c\u6301\u7e8c\u7684\u75b2\u618a<\/li>\n<li>\u9ad4\u91cd\u610f\u5916\u6e1b\u8f15\u548c\u98df\u617e\u4e0d\u632f<\/li>\n<li>\u56e0\u816b\u7624\u58d3\u8feb\u795e\u7d93\u800c\u5c0e\u81f4\u8072\u97f3\u6c99\u555e\u6216\u8072\u97f3\u6539\u8b8a<\/li>\n<li>\u9838\u90e8\u6216\u81c9\u90e8\u56e0\u6dcb\u5df4\u7d50\u816b\u5927\u6216\u975c\u8108\u963b\u585e\u800c\u816b\u8139<\/li>\n<li>\u610f\u5916\u767c\u751f\u7684\u9aa8\u75db\u6216\u9aa8\u6298\uff08\u901a\u5e38\u8868\u793a\u8f49\u79fb\u64f4\u6563\uff09<\/li>\n<\/ul>\n<p>\u975e\u5c0f\u7d30\u80de\u80ba\u764c (NSCLC) \u75c7\u72c0\u8207\u816b\u7624\u751f\u7269\u5b78\u76f4\u63a5\u76f8\u95dc\u3002\u764c\u7d30\u80de\u7684\u751f\u9577\u6703\u963b\u585e\u6c23\u9053\uff0c\u58d3\u8feb\u795e\u7d93\u548c\u8840\u7ba1\u7b49\u5468\u570d\u7d50\u69cb\uff0c\u4e26\u56e0\u7d30\u80de\u6fc0\u7d20\u5347\u9ad8\u548c\u4ee3\u8b1d\u7d0a\u4e82\u800c\u5f15\u8d77\u5168\u8eab\u75c7\u72c0\u3002\u9451\u65bc\u975e\u5c0f\u7d30\u80de\u80ba\u764c\u7d30\u80de\u5c0d\u52a0\u901f\u8461\u8404\u7cd6\u4ee3\u8b1d\u7684\u4f9d\u8cf4\uff08\u74e6\u723e\u5821\u6548\u61c9\uff09\uff0c\u9ad4\u91cd\u6e1b\u8f15\u548c\u75b2\u52de\u7b49\u986f\u8457\u7684\u5168\u8eab\u75c7\u72c0\u7d93\u5e38\u51fa\u73fe\u8f03\u65e9\u3002\u65e9\u671f\u91ab\u5b78\u8a55\u4f30\u5c0d\u65bc\u7dad\u6301\u60a3\u8005\u5065\u5eb7\u548c\u63d0\u9ad8\u5b58\u6d3b\u7387\u4ecd\u7136\u81f3\u95dc\u91cd\u8981\u3002<\/p>\n<p>\u5982\u679c\u6301\u7e8c\u51fa\u73fe\u4e00\u7a2e\u6216\u591a\u7a2e\u75c7\u72c0\uff0c\u53ca\u6642\u8aee\u8a62\u91ab\u7642\u4fdd\u5065\u63d0\u4f9b\u8005\u81f3\u95dc\u91cd\u8981\u3002\u65e9\u671f\u6aa2\u6e2c\u5927\u5927\u63d0\u9ad8\u4e86\u6a19\u9776\u6cbb\u7642\u548c 4D \u7642\u6cd5\u7b49\u500b\u4eba\u5316\u4ee3\u8b1d\u6cbb\u7642\u7b49\u6cbb\u7642\u7684\u6709\u6548\u6027\u3002 <a href=\"\/zh-hk\/diagnostics.html\/\">\u4e86\u89e3\u6709\u95dc NSCLC \u8a3a\u65b7\u9078\u64c7\u7684\u66f4\u591a\u8cc7\u8a0a\u3002<\/a><\/p>\n<h2 id=\"stages-of-non-small-cell-lung-cancer-nsclc-and-survival-rates\">\u975e\u5c0f\u7d30\u80de\u80ba\u764c (NSCLC) \u7684\u5206\u671f\u548c\u5b58\u6d3b\u7387<\/h2>\n<p>\u4e86\u89e3\u975e\u5c0f\u7d30\u80de\u80ba\u764c (NSCLC) \u7684\u5206\u671f\u53ef\u70ba\u9810\u5f8c\u63d0\u4f9b\u6709\u50f9\u503c\u7684\u898b\u89e3\u4e26\u6307\u5c0e\u6a19\u9776\u6cbb\u7642\u7b56\u7565\u3002\u5206\u671f\u7cfb\u7d71\u8a55\u4f30\u816b\u7624\u5927\u5c0f\u3001\u6dcb\u5df4\u7d50\u53d7\u7d2f\u548c\u8f49\u79fb\u9032\u5c55\uff0c\u8207\u5b58\u6d3b\u6a5f\u7387\u548c\u5efa\u8b70\u6cbb\u7642\u76f4\u63a5\u76f8\u95dc\u3002<\/p>\n<h3 id=\"stage-1-non-small-cell-lung-cancer-nsclc\">\u7b2c\u4e00\u968e\u6bb5 \u2013 \u975e\u5c0f\u7d30\u80de\u80ba\u764c (NSCLC)<\/h3>\n<p>\u4f5c\u70ba NSCLC \u6700\u65e9\u53ef\u8b58\u5225\u7684\u968e\u6bb5\uff0c\u7b2c\u4e00\u968e\u6bb5\u6d89\u53ca\u56b4\u683c\u5c40\u9650\u65bc\u80ba\u90e8\u7684\u5c40\u90e8\u816b\u7624\u3002\u901a\u5e38\uff0c\u816b\u7624\u5c3a\u5bf8\u5c0f\u65bc 3 \u5398\u7c73\uff0c\u6c92\u6709\u4efb\u4f55\u6dcb\u5df4\u7d50\u53d7\u7d2f\u6216\u8f49\u79fb\u3002<\/p>\n<ul>\n<li>\u624b\u8853\u5207\u9664\u4ecd\u662f\u6cbb\u7642\u7684\u57fa\u77f3<\/li>\n<li>\u7576\u624b\u8853\u7981\u5fcc\u6642\uff0c\u653e\u5c04\u7642\u6cd5\u548c\u6a19\u9776\u4ee3\u8b1d\u7642\u6cd5\u53ef\u63d0\u4f9b\u6709\u6548\u7684\u6cbb\u7642\u9078\u64c7<\/li>\n<li>\u4e94\u5e74\u5b58\u6d3b\u7387\u53ef\u8d85\u904e 70-90%\uff0c\u51f8\u986f\u65e9\u671f\u6aa2\u6e2c\u548c\u8fc5\u901f\u81e8\u5e8a\u4ecb\u5165\u7684\u8feb\u5207\u6027<\/li>\n<\/ul>\n<h3 id=\"stage-2-non-small-cell-lung-cancer-nsclc\">\u7b2c 2 \u671f \u2013 \u975e\u5c0f\u7d30\u80de\u80ba\u764c (NSCLC)<\/h3>\n<p>\u6b64\u968e\u6bb5\u816b\u7624\u8f03\u5927\uff0c\u4e00\u822c\u57283-5\u516c\u5206\u4e4b\u9593\uff0c\u4e26\u6d89\u53ca\u5c40\u90e8\u6dcb\u5df4\u7d50\u6216\u80ba\u90e8\u8f03\u6df1\u7684\u7d44\u7e54\u3002\u7531\u65bc\u74e6\u723e\u5821\u6548\u61c9\u800c\u5c0e\u81f4\u7684\u4ee3\u8b1d\u9700\u6c42\u589e\u52a0\u5728\u5168\u8eab\u75c7\u72c0\u4e2d\u8b8a\u5f97\u660e\u986f\u3002<\/p>\n<ul>\n<li>\u5728\u53ef\u884c\u7684\u60c5\u6cc1\u4e0b\uff0c\u624b\u8853\u5207\u9664\u4ecd\u7136\u975e\u5e38\u6709\u5229<\/li>\n<li>\u901a\u5e38\u63a1\u7528\u8f14\u52a9\u5316\u7642\u548c\u653e\u5c04\u6cbb\u7642\uff0c\u65e8\u5728\u6d88\u9664\u764c\u7d30\u80de\u7684\u5fae\u5c0f\u6b98\u7559<\/li>\n<li>\u4ee3\u8b1d\u7642\u6cd5\u7684\u4f7f\u7528\uff0c\u91cd\u9ede\u5728\u65bc\u764c\u7d30\u80de\u5728\u8461\u8404\u7cd6\u548c\u8c37\u6c28\u9170\u80fa\u4ee3\u8b1d\u4e2d\u7684\u8106\u5f31\u6027\uff0c\u5448\u73fe\u51fa\u6709\u524d\u666f\u7684\u6cbb\u7642\u5275\u65b0<\/li>\n<li>\u4e94\u5e74\u5b58\u6d3b\u7387\u7d04 50-70%\uff0c\u900f\u904e\u7d9c\u5408\u6cbb\u7642\u5177\u6709\u5de8\u5927\u7684\u6539\u5584\u6f5b\u529b<\/li>\n<\/ul>\n<h3 id=\"stage-3-non-small-cell-lung-cancer-nsclc\">\u7b2c 3 \u671f \u2013 \u975e\u5c0f\u7d30\u80de\u80ba\u764c (NSCLC)<\/h3>\n<p>3 \u671f NSCLC \u8868\u793a\u665a\u671f\u5c40\u90e8\u75be\u75c5\u3002\u764c\u75c7\u5ee3\u6cdb\u4fb5\u5165\u9644\u8fd1\u7684\u6dcb\u5df4\u7d50\uff0c\u4e26\u53ef\u80fd\u767c\u751f\u816b\u7624\u76f4\u63a5\u64f4\u6563\u5230\u80f8\u58c1\u6216\u4e3b\u8981\u6c23\u9053\u7b49\u5468\u570d\u7d44\u7e54\u3002<\/p>\n<ul>\n<li>\u6cbb\u7642\u5305\u62ec\u5316\u7642\u3001\u653e\u7642\uff0c\u6709\u6642\u9084\u5305\u62ec\u624b\u8853\u7684\u591a\u6a21\u5f0f\u7d44\u5408\uff0c\u53d6\u6c7a\u65bc\u816b\u7624\u7684\u53ef\u64cd\u4f5c\u6027\u548c\u60a3\u8005\u7684\u5065\u5eb7\u72c0\u6cc1<\/li>\n<li>\u8afe\u8c9d\u723e\u734e\u5f97\u4e3b James Allison \u535a\u58eb\u548c Gregg Semenza \u535a\u58eb\u958b\u5275\u7684\u6a19\u9776\u7642\u6cd5\u548c\u514d\u75ab\u7642\u6cd5\u63d0\u4f9b\u4e86\u984d\u5916\u7684\u7b56\u7565\u66ff\u4ee3\u65b9\u6848\uff0c\u4ee3\u8b1d\u7642\u6cd5\u6b63\u5728\u7a4d\u6975\u7814\u7a76\u4e2d<\/li>\n<li>\u6301\u7e8c\u7684\u5275\u65b0\u5df2\u5c07 3 \u671f NSCLC \u7684\u4e94\u5e74\u5b58\u6d3b\u7387\u63d0\u9ad8\u81f3 30-55%\uff0c\u9019\u5c0d\u63a8\u9032\u4ee3\u8b1d\u6cbb\u7642\u7b56\u7565\u5177\u6709\u5f37\u5927\u7684\u52d5\u529b<\/li>\n<\/ul>\n<h3 id=\"stage-4-non-small-cell-lung-cancer-nsclc\">\u7b2c 4 \u671f \u2013 \u975e\u5c0f\u7d30\u80de\u80ba\u764c (NSCLC)<\/h3>\n<p>\u7b2c 4 \u671f NSCLC \u4ee3\u8868\u8f49\u79fb\u6027\u75be\u75c5\uff0c\u764c\u7d30\u80de\u5df2\u900f\u904e\u8840\u6d41\u6216\u6dcb\u5df4\u9014\u5f91\u64f4\u6563\u5230\u9060\u7aef\u90e8\u4f4d\uff0c\u4f8b\u5982\u5927\u8166\u3001\u809d\u81df\u3001\u9aa8\u9abc\u6216\u814e\u4e0a\u817a\u3002\u9019\u4e00\u968e\u6bb5\u7684\u9810\u5f8c\u6311\u6230\u986f\u8457\u589e\u52a0\uff0c\u51f8\u986f\u4e86\u7b56\u7565\u6027\u75be\u75c5\u7ba1\u7406\u7684\u8feb\u5207\u6027\u3002<\/p>\n<ul>\n<li>\u5305\u62ec\u5316\u7642\u3001\u6a19\u9776\u6cbb\u7642\u548c\u514d\u75ab\u6aa2\u67e5\u9ede\u6291\u5236\u5291\u5728\u5167\u7684\u5168\u8eab\u6027\u6cbb\u7642\u662f\u7ba1\u7406\u548c\u53ef\u80fd\u63a7\u5236\u75be\u75c5\u9032\u5c55\u7684\u6838\u5fc3\u65b9\u6cd5<\/li>\n<li>\u5728\u5ee3\u6cdb\u7814\u7a76\u548c\u5168\u7403\u5408\u4f5c\u7684\u652f\u6301\u4e0b\uff0c\u91dd\u5c0d\u7368\u7279\u764c\u7d30\u80de\u751f\u7269\u80fd\u7684\u5275\u65b0\u4ee3\u8b1d\u7642\u6cd5\u81f4\u529b\u65bc\u5c07 NSCLC \u8f49\u8b8a\u70ba\u53ef\u63a7\u5236\u7684\u6162\u6027\u75be\u75c5<\/li>\n<li>\u300c\u5148\u6cbb\u6108\uff0c\u5f8c\u4ed8\u8cbb\u300d\u652f\u4ed8\u653f\u7b56\u7b49\u8209\u63aa\u4ee5\u53ca\u8207 MD \u5b89\u5fb7\u68ee\u548c\u6df1\u5733\u524d\u6d77\u6cf0\u5eb7\u7b49\u5168\u7403\u77e5\u540d\u6a5f\u69cb\u7684\u5408\u4f5c\u5f37\u8abf\u4e86\u60a3\u8005\u7372\u5f97\u7a81\u7834\u6027\u6cbb\u7642\u7684\u6a5f\u6703<\/li>\n<li>\u5118\u7ba1\u4e09\u5e74\u5b58\u6d3b\u7387\u70ba 10-30% \u7684\u6b77\u53f2\u5b58\u6d3b\u7387\uff0c\u4f46\u6839\u690d\u65bc\u4ee3\u8b1d\u548c\u514d\u75ab\u5b78\u7406\u89e3\u7684\u6301\u7e8c\u6cbb\u7642\u5275\u65b0\u6709\u671b\u986f\u8457\u6539\u5584\u7d50\u679c\u548c\u751f\u6d3b\u8cea\u91cf<\/li>\n<\/ul>\n<p>\u6bcf\u500b NSCLC \u968e\u6bb5\u90fd\u53cd\u6620\u4e86\u4e0d\u540c\u7684\u751f\u7269\u5b78\u73fe\u8c61\uff0c\u53d7\u5230\u7368\u7279\u7684\u764c\u75c7\u4ee3\u8b1d\u3001\u751f\u9577\u884c\u70ba\u548c\u514d\u75ab\u7cfb\u7d71\u76f8\u4e92\u4f5c\u7528\u7684\u5f71\u97ff\u3002\u6191\u85c9\u8afe\u8c9d\u723e\u734e\u5f97\u4e3b\u7814\u7a76\u7684\u6301\u7e8c\u5275\u65b0\u4ee5\u53ca\u674e\u570b\u83ef\u535a\u58eb\u548c\u5289\u570b\u9f8d\u6559\u6388\u7b49\u5c08\u696d\u4eba\u58eb\u5ee3\u6cdb\u7684\u81e8\u5e8a\u5c08\u696d\u77e5\u8b58\uff0c\u5168\u9762\u7684\u81e8\u5e8a\u65b9\u6cd5\u63d0\u4f9b\u4e86\u512a\u5316\u7684\u60a3\u8005\u8b77\u7406\u8def\u5f91\uff0c\u65e8\u5728\u986f\u8457\u6539\u5584\u6574\u500b\u9999\u6e2f\u548c\u4e9e\u6d32\u7684\u6cbb\u7642\u7d50\u679c\u3002 <a href=\"\/zh-hk\/treatment-options.html\/\">\u63a2\u7d22 NSCLC \u7684\u8a73\u7d30\u6cbb\u7642\u65b9\u6848\u3002<\/a><\/p>\n<h2 id=\"limitations-of-traditional-therapies-for-non-small-cell-lung-cancer-nsclc\">\u975e\u5c0f\u7d30\u80de\u80ba\u764c (NSCLC) \u50b3\u7d71\u7642\u6cd5\u7684\u5c40\u9650\u6027<\/h2>\n<h3 id=\"chemotherapy-a-double-edged-sword-in-nsclc-treatment\">\u5316\u5b78\u6cbb\u7642\uff1a\u975e\u5c0f\u7d30\u80de\u80ba\u764c\u6cbb\u7642\u7684\u96d9\u9762\u5203<\/h3>\n<p>\u5316\u7642\u4ecd\u7136\u662f\u975e\u5c0f\u7d30\u80de\u80ba\u764c\uff08NSCLC\uff09\u6cbb\u7642\u7684\u57fa\u77f3\uff1b\u7136\u800c\uff0c\u5316\u7642\u5f15\u8d77\u7684\u6bd2\u6027\u7684\u6b98\u9177\u73fe\u5be6\u4e0d\u5bb9\u5ffd\u8996\u3002\u50b3\u7d71\u5316\u7642\u4ee5\u5feb\u901f\u5206\u88c2\u7684\u764c\u7d30\u80de\u70ba\u76ee\u6a19\uff0c\u4f46\u4e5f\u6703\u5f71\u97ff\u5065\u5eb7\u589e\u6b96\u7684\u7d30\u80de\uff0c\u5c0e\u81f4\u9aa8\u9ad3\u6291\u5236\u7b49\u4f7f\u4eba\u8870\u5f31\u7684\u526f\u4f5c\u7528\uff08\u767c\u751f\u7387 78%\uff09\uff0c\u986f\u8457\u589e\u52a0\u60a3\u8005\u5c0d\u611f\u67d3\u3001\u8ca7\u8840\u548c\u51fa\u8840\u4e26\u767c\u75c7\u7684\u8106\u5f31\u6027\uff0c\u6b63\u5982\u6700\u8fd1\u7684\u300a\u7f8e\u570b\u91ab\u5b78\u6703\u96dc\u8a8c\u300b\u816b\u7624\u5b78\u7814\u7a76 (2023) \u6240\u5831\u544a\u7684\u90a3\u6a23\u3002<\/p>\n<p>\u6b64\u5916\uff0c\u5316\u7642\u7684\u975e\u7279\u7570\u6027\u9084\u6703\u5c0e\u81f4\u9ad8\u9054 23% \u7684\u63a5\u53d7\u5e38\u7528\u5316\u7642\u85e5\u7269\uff08\u5982\u963f\u9ef4\u7d20\u548c\u74b0\u78f7\u9170\u80fa\uff09\u6cbb\u7642\u7684\u60a3\u8005\u51fa\u73fe\u56b4\u91cd\u7684\u5fc3\u81df\u6bd2\u6027\uff0c\u9019\u51f8\u986f\u4e86\u4e00\u500b\u56b4\u91cd\u7684\u98a8\u96aa\uff0c\u7279\u5225\u662f\u5c0d\u65bc\u8001\u5e74\u60a3\u8005\u6216\u5728\u9999\u6e2f\u548c\u6574\u500b\u4e9e\u6d32\u8001\u9f61\u5316\u4eba\u7fa4\u4e2d\u666e\u904d\u5b58\u5728\u5fc3\u81df\u75c5\u7684\u60a3\u8005\u3002<\/p>\n<ul>\n<li>\u9aa8\u9ad3\u6291\u5236\u98a8\u96aa\uff1a78%<\/li>\n<li>\u5fc3\u81df\u6bd2\u6027\uff1a23%<\/li>\n<li>\u56b4\u91cd\u5641\u5fc3\u548c\u5614\u5410\uff1a&gt;70%\u7684\u60a3\u8005<\/li>\n<li>\u9700\u8981\u4f4f\u9662\u6cbb\u7642\u7684\u611f\u67d3\u98a8\u96aa\u589e\u52a0\uff1a60%<\/li>\n<\/ul>\n<p>\u6b64\u5916\uff0c\u5316\u7642\u5e38\u5e38\u7121\u6cd5\u70ba\u665a\u671f NSCLC \u63d0\u4f9b\u6301\u4e45\u7684\u6cbb\u7642\u76ca\u8655\uff0c\u5728\u8f49\u79fb\u60c5\u6cc1\u4e0b\u5ba2\u89c0\u7de9\u89e3\u7387\u964d\u81f3 21% \u4ee5\u4e0b\u3002\u9019\u6975\u5927\u5730\u9650\u5236\u4e86\u4e9e\u6d32\u4eba\u7fa4\u4e2d\u666e\u904d\u5b58\u5728\u7684\u665a\u671f\u8a3a\u65b7\u7684\u7642\u6548\uff0c\u9700\u8981\u66f4\u6709\u91dd\u5c0d\u6027\u548c\u53ef\u8010\u53d7\u7684\u7b56\u7565\u4f86\u6cbb\u7642\u975e\u5c0f\u7d30\u80de\u80ba\u764c (NSCLC)\u3002<\/p>\n<h3 id=\"radiation-therapy-not-without-consequences\">\u653e\u5c04\u6cbb\u7642\uff1a\u4e26\u975e\u6c92\u6709\u5f8c\u679c<\/h3>\n<p>\u653e\u5c04\u6cbb\u7642\u96d6\u7136\u5c0d\u65bc NSCLC \u7684\u5c40\u90e8\u75be\u75c5\u63a7\u5236\u5f88\u6709\u50f9\u503c\uff0c\u4f46\u7531\u65bc\u5176\u7834\u58de\u7d30\u80de DNA \u7684\u5167\u5728\u6a5f\u5236\uff0c\u4e0d\u53ef\u907f\u514d\u5730\u6703\u5e36\u4f86\u91cd\u5927\u98a8\u96aa\u3002\u764c\u7d30\u80de\u9644\u8fd1\u7684\u5065\u5eb7\u7d44\u7e54\u4e0d\u53ef\u907f\u514d\u5730\u53d7\u5230\u8f3b\u5c04\u7167\u5c04\uff0c\u53ef\u80fd\u5c0e\u81f4\u653e\u5c04\u6027\u80ba\u708e\u3001\u7e96\u7dad\u5316\u3001\u7d44\u7e54\u75a4\u75d5\u548c\u80ba\u529f\u80fd\u9577\u671f\u4e0b\u964d\u3002\u6578\u64da\u986f\u793a\uff0c\u7d04 40% \u63a5\u53d7\u80f8\u90e8\u7167\u5c04\u7684\u60a3\u8005\u6703\u51fa\u73fe\u81e8\u5e8a\u4e0a\u986f\u8457\u7684\u80ba\u90e8\u708e\u75c7\uff0c\u56b4\u91cd\u5f71\u97ff\u4ed6\u5011\u7684\u547c\u5438\u80fd\u529b\u548c\u751f\u6d3b\u54c1\u8cea\uff08JAMA Oncology\uff0c2023\uff09\u3002<\/p>\n<ul>\n<li>\u653e\u5c04\u6027\u80ba\u708e\uff1a\u5831\u544a\u75c5\u4f8b\u9ad8\u9054 40%<\/li>\n<li>\u7e96\u7dad\u5316\u548c\u80ba\u529f\u80fd\u4e0b\u964d\uff1a\u5f71\u97ff\u9577\u671f\u751f\u6d3b\u54c1\u8cea<\/li>\n<li>\u75b2\u52de\u548c\u865b\u5f31\u5728\u6cbb\u7642\u5f8c\u6301\u7e8c\u6578\u6708<\/li>\n<\/ul>\n<p>\u6b64\u5916\uff0c\u8f3b\u5c04\u8a98\u767c\u7684\u7e7c\u767c\u6027\u764c\u75c7\u5448\u73fe\u51fa\u4ee4\u4eba\u75db\u82e6\u7684\u589e\u9577\u8da8\u52e2\uff0c\u6709\u5831\u544a\u986f\u793a\uff0c\u63a5\u53d7\u653e\u5c04\u6cbb\u7642\u7684\u60a3\u8005\u5728\u6cbb\u7642\u5e7e\u5341\u5e74\u5f8c\u767c\u751f\u7e7c\u767c\u6027\u60e1\u6027\u816b\u7624\u7684\u98a8\u96aa\u589e\u52a0\u4e86 300%\uff0c\u9019\u51f8\u986f\u4e86\u9999\u6e2f\u548c\u66f4\u5ee3\u6cdb\u7684\u4e9e\u6d32\u91ab\u7642\u4fdd\u5065\u7cfb\u7d71\u8feb\u5207\u9700\u8981\u5275\u65b0\u7684\u6cbb\u7642\u9014\u5f91\u3002<\/p>\n<h3 id=\"surgical-intervention-and-its-associated-risks\">\u624b\u8853\u4ecb\u5165\u53ca\u5176\u76f8\u95dc\u98a8\u96aa<\/h3>\n<p>\u7576\u75be\u75c5\u53ca\u65e9\u767c\u73fe\u6642\uff0c\u975e\u5c0f\u7d30\u80de\u80ba\u764c\u7684\u624b\u8853\u901a\u5e38\u63d0\u4f9b\u6700\u6709\u5e0c\u671b\u7684\u6cbb\u7652\u524d\u666f\u3002\u7136\u800c\uff0c\u624b\u8853\u6cbb\u7642\u6709\u76f8\u7576\u5927\u7684\u98a8\u96aa\uff0c\u4e3b\u8981\u8207\u4fb5\u5165\u6027\u624b\u8853\u7684\u4f75\u767c\u75c7\u6709\u95dc\u3002\u6839\u64da\u4e9e\u6d32\u816b\u7624\u5b78\u5be6\u8e10\u7684\u6700\u65b0\u6578\u64da\uff0c\u624b\u8853\u4ecb\u5165\u901a\u5e38\u6703\u5e36\u4f86\u8853\u5f8c\u4f75\u767c\u75c7\u548c\u8f03\u9577\u7684\u6062\u5fa9\u671f\uff0c\u9019\u5c0d\u65bc\u9999\u6e2f\u666e\u904d\u5b58\u5728\u7684\u8001\u5e74\u4eba\u4f86\u8aaa\u5c24\u5176\u5177\u6709\u6311\u6230\u6027\uff0c\u56e0\u70ba\u5728\u9999\u6e2f\uff0c\u80ba\u764c\u5728 60 \u6b72\u53ca\u4ee5\u4e0a\u7684\u6210\u5e74\u4eba\u4e2d\u767c\u75c5\u7387\u6700\u9ad8\u3002<\/p>\n<ul>\n<li>\u624b\u8853\u5f8c\u611f\u67d3\uff1a\u9ad8\u9054 25%<\/li>\n<li>30% \u7684\u8001\u5e74\u60a3\u8005\u4f4f\u9662\u6642\u9593\u5ef6\u9577\u4e14\u6062\u5fa9\u7de9\u6162\uff08&gt;21 \u5929\uff09<\/li>\n<li>\u8853\u5f8c\u6162\u6027\u75bc\u75db\u548c\u547c\u5438\u529f\u80fd\u53d7\u640d<\/li>\n<li>\u8001\u5e74\u6216\u5408\u4f75\u75c7\u60a3\u8005\u7684\u624b\u8853\u98a8\u96aa\u5347\u9ad8\uff0c\u9019\u5728\u4e9e\u6d32\u4eba\u7fa4\u4e2d\u5f88\u5e38\u898b<\/li>\n<\/ul>\n<p>\u9019\u4e9b\u56e0\u7d20\u5927\u5927\u9650\u5236\u4e86\u624b\u8853\u7684\u53ef\u884c\u6027\uff0c\u7279\u5225\u662f\u5728\u9999\u6e2f\u548c\u6771\u4e9e\u7b49\u5730\u5340\uff0c\u665a\u671f\u8a3a\u65b7\u548c\u8001\u5e74\u60a3\u8005\u7684\u6bd4\u4f8b\u5f88\u9ad8\uff0c\u56e0\u6b64\u9700\u8981\u6539\u9032\u8a3a\u65b7\u548c\u5fae\u5275\u6cbb\u7642\u65b9\u6848\u3002<\/p>\n<h3 id=\"metabolic-and-genetic-resistance-mechanisms-in-nsclc-cells\">NSCLC\u7d30\u80de\u7684\u4ee3\u8b1d\u548c\u907a\u50b3\u6297\u6027\u6a5f\u5236<\/h3>\n<p>\u50b3\u7d71\u7642\u6cd5\u4e2d\u4e00\u500b\u88ab\u56b4\u91cd\u5ffd\u8996\u7684\u65b9\u9762\u662f\u764c\u7d30\u80de\u7684\u4ee3\u8b1d\u548c\u907a\u50b3\u9069\u61c9\u80fd\u529b\uff0c\u9019\u4e00\u9ede\u5728\u6700\u8fd1\u7684\u975e\u5c0f\u7d30\u80de\u80ba\u764c\u7814\u7a76\u4e2d\u8b8a\u5f97\u8d8a\u4f86\u8d8a\u660e\u986f\u3002\u816b\u7624\u7d30\u80de\u5229\u7528\u74e6\u723e\u5821\u6548\u61c9\u7b49\u4ee3\u8b1d\u9014\u5f91\uff0c\u6d88\u8017\u8461\u8404\u7cd6\u7684\u901f\u5ea6\u7d04\u70ba\u6b63\u5e38\u7d30\u80de\u7684 200 \u500d\uff0c\u9019\u662f\u4e00\u7a2e\u7dad\u6301\u5c0d\u50b3\u7d71\u7642\u6cd5\u6297\u85e5\u6027\u7684\u751f\u5b58\u6a5f\u5236\u3002<\/p>\n<p>\u6b64\u5916\uff0cNSCLC \u7d30\u80de\u8868\u73fe\u51fa\u589e\u5f37\u7684\u4ee3\u8b1d\u9a45\u52d5\u7684\u6297\u85e5\u6027\u6a5f\u5236\uff0c\u5176\u7279\u5fb5\u662f DNA \u4fee\u5fa9\u9176\u6d3b\u6027\u9a5a\u4eba\u5730\u589e\u52a0\u4e86 400%\u3002\u9019\u7a2e\u589e\u5f37\u7684\u9175\u7d20\u6d3b\u6027\u4f7f\u816b\u7624\u7d30\u80de\u80fd\u5920\u62b5\u6297\u50b3\u7d71\u5316\u7642\u548c\u653e\u7642\u7684\u640d\u50b7\uff0c\u5f9e\u800c\u5c0e\u81f4\u6cbb\u7642\u6548\u679c\u964d\u4f4e\u548c\u816b\u7624\u5fa9\u767c\u2014\u2014\u9019\u662f\u9999\u6e2f\u548c\u4e9e\u592a\u5730\u5340\u6210\u529f\u6cbb\u7642\u975e\u5c0f\u7d30\u80de\u80ba\u764c\u75c5\u4f8b\u7684\u4e3b\u8981\u6311\u6230\u3002<\/p>\n<h3 id=\"the-psychological-and-emotional-toll-of-traditional-therapies\">\u50b3\u7d71\u7642\u6cd5\u7684\u5fc3\u7406\u8207\u60c5\u7dd2\u4ee3\u50f9<\/h3>\n<p>\u9664\u4e86\u8eab\u9ad4\u4e0a\u7684\u9650\u5236\u4e4b\u5916\uff0c\u50b3\u7d71\u7684\u975e\u5c0f\u7d30\u80de\u80ba\u764c\u6cbb\u7642\u4e5f\u5c0d\u60a3\u8005\u53ca\u5176\u5bb6\u4eba\u7522\u751f\u91cd\u5927\u7684\u5fc3\u7406\u548c\u60c5\u7dd2\u5f71\u97ff\u3002\u5316\u7642\u548c\u653e\u7642\u7684\u526f\u4f5c\u7528\u901a\u5e38\u5305\u62ec\u56b4\u91cd\u75b2\u52de\u3001\u6182\u9b31\u3001\u7126\u616e\uff0c\u4ee5\u53ca\u5728\u6f2b\u9577\u7684\u6cbb\u7642\u9031\u671f\u4e2d\u5c0d\u5fc3\u7406\u5065\u5eb7\u7684\u91cd\u5927\u5f71\u97ff\u3002\u9019\u7a2e\u60c5\u7dd2\u8ca0\u64d4\uff0c\u52a0\u4e0a\u4e0d\u78ba\u5b9a\u7684\u6cbb\u7642\u7d50\u679c\u548c\u6301\u7e8c\u9ad8\u7684\u5fa9\u767c\u7387\uff0c\u56b4\u91cd\u640d\u5bb3\u4e86\u60a3\u8005\u7684\u751f\u6d3b\u8cea\u91cf\uff0c\u4e26\u9020\u6210\u4e86\u6cbb\u7642\u6182\u616e\u3002<\/p>\n<ul>\n<li>\u6301\u7e8c\u75b2\u52de\u5f71\u97ff\u8d85\u904e 70% \u7684\u60a3\u8005<\/li>\n<li>\u6cbb\u7642\u65cf\u7fa4\u4e2d\u56b4\u91cd\u7126\u616e\u548c\u6182\u9b31\u7684\u6bd4\u4f8b\u9ad8\u9054 50%<\/li>\n<li>\u9ad8\u5fa9\u767c\u4e0d\u78ba\u5b9a\u6027\u6703\u7522\u751f\u60c5\u7dd2\u56f0\u64fe<\/li>\n<\/ul>\n<h3 id=\"concluding-remarks-the-urgent-need-for-innovation-in-nsclc-care\">\u7d50\u8ad6\uff1a\u975e\u5c0f\u7d30\u80de\u80ba\u764c\u6cbb\u7642\u8feb\u5207\u9700\u8981\u5275\u65b0<\/h3>\n<p>\u9451\u65bc\u50b3\u7d71\u7642\u6cd5\u6709\u5ee3\u6cdb\u7684\u9650\u5236\u548c\u6709\u5bb3\u7684\u526f\u4f5c\u7528\uff0c\u5f88\u660e\u986f\u76ee\u524d\u7684\u7642\u6cd5\u5728\u6709\u6548\u6cbb\u7642\u665a\u671f\u975e\u5c0f\u7d30\u80de\u80ba\u764c\uff08NSCLC\uff09\u65b9\u9762\u5b58\u5728\u4e0d\u8db3\u3002\u81e8\u5e8a\u3001\u8eab\u9ad4\u548c\u60c5\u611f\u65b9\u9762\u7684\u5229\u5bb3\u95dc\u4fc2\u8868\u660e\uff0c\u8feb\u5207\u9700\u8981\u5275\u65b0\u6cbb\u7642\u65b9\u6cd5\uff0c\u5229\u7528\u6211\u5011\u5c0d\u4ee3\u8b1d\u816b\u7624\u5b78\u548c\u6a19\u9776\u6cbb\u7642\u65e5\u76ca\u52a0\u6df1\u7684\u7406\u89e3\uff0c\u4f8b\u5982\u7531\u8afe\u8c9d\u723e\u734e\u7372\u734e\u767c\u73fe\u652f\u6301\u7684\u958b\u5275\u6027 4D \u6cbb\u7642\u65b9\u6cd5\u3002<\/p>\n<p>\u65e9\u671f\u8a3a\u65b7\uff0c\u52a0\u4e0a\u5f37\u8abf\u6700\u5c0f\u5316\u6bd2\u6027\u548c\u63d0\u9ad8\u751f\u6d3b\u54c1\u8cea\u7684\u7a81\u7834\u6027\u6cbb\u7642\uff0c\u5448\u73fe\u51fa\u89f8\u624b\u53ef\u53ca\u7684\u6a02\u89c0\u672a\u4f86\u2014\u2014\u9019\u8207 AllCancer \u4f7f\u975e\u5c0f\u7d30\u80de\u80ba\u764c\u6210\u70ba\u53ef\u63a7\u5236\u7684\u6162\u6027\u5065\u5eb7\u72c0\u6cc1\u7684\u96c4\u5fc3\u52c3\u52c3\u7684\u76ee\u6a19\u7dca\u5bc6\u7d50\u5408\u3002<\/p>\n<h2>\u56db\u7dad\u7121\u6bd2\u764c\u75c7\u7642\u6cd5\u6cbb\u7642\u65b9\u6cd5<\/h2>\n<p>\u9999\u6e2f\u4ee3\u8b1d\u816b\u7624\u6cbb\u7642\u4e2d\u5fc3\u63d0\u51fa\u7684\u56db\u7dad\u7121\u6bd2\u7642\u6cd5\u4ee3\u8868\u4e86\u4e00\u7a2e\u591a\u5c64\u9762\u7684\u764c\u75c7\u6cbb\u7642\u65b9\u6cd5\uff0c\u65e8\u5728\u5c07\u764c\u75c7\u8f49\u8b8a\u70ba\u53ef\u63a7\u5236\u7684\u6162\u6027\u75be\u75c5\u3002\u672c\u8abf\u67e5\u5831\u544a\u57fa\u65bc\u6240\u63d0\u4f9b\u7684\u6587\u4ef6\uff0c\u4e26\u900f\u904e\u57fa\u65bc\u7db2\u8def\u7684\u79d1\u5b78\u6587\u737b\u7684\u5ee3\u6cdb\u7814\u7a76\u9032\u884c\u4e86\u88dc\u5145\uff0c\u5c0d\u56db\u7a2e\u65b9\u6cd5\uff08\u4ee3\u8b1d\u6291\u5236\u3001\u7bc0\u5f8b\u6027\u816b\u7624\u63a7\u5236\u3001\u57fa\u56e0\u9776\u5411\u65ac\u9996\u548c\u514d\u75ab\u98a8\u66b4\u6fc0\u6d3b\uff09\u9032\u884c\u4e86\u5168\u9762\u5206\u6790\u3002\u5206\u6790\u5305\u62ec\u79d1\u5b78\u539f\u7406\u3001\u81e8\u5e8a\u8b49\u64da\u548c\u6f5b\u5728\u6311\u6230\uff0c\u6700\u7d42\u63d0\u51fa\u4e86\u53e3\u865f\u548c\u53e3\u865f\u3002<\/p>\n<h3>\u4ee3\u8b1d\u6291\u5236<\/h3>\n<p><strong>\u7e3d\u7d50\u8207\u6a5f\u5236<\/strong>\uff1a\u9019\u7a2e\u65b9\u6cd5\u91dd\u5c0d\u764c\u7d30\u80de\u7684\u4ee3\u8b1d\u8106\u5f31\u6027\uff0c\u7279\u5225\u662f\u5b83\u5011\u5c0d\u8461\u8404\u7cd6\u3001\u9ea9\u91af\u80fa\u9178\u548c\u8102\u8cea\u5408\u6210\u7684\u4f9d\u8cf4\u3002\u5b83\u4f7f\u7528\u8af8\u5982\u7528\u65bc\u8461\u8404\u7cd6\u8f49\u904b\u7684 GLUT1\/3\u3001\u7528\u65bc\u8c37\u6c28\u9170\u80fa\u4ee3\u8b1d\u7684 GLS\/ASCT2 \u4ee5\u53ca\u7528\u65bc\u8102\u8cea\u5408\u6210\u7684 FASN \u7b49\u6291\u5236\u5291\uff0c\u901a\u5e38\u900f\u904e\u5948\u7c73\u8f09\u9ad4\u905e\u9001\u3002\u4eba\u5de5\u667a\u6167\u9a45\u52d5\u7684\u71df\u990a\u8abf\u7bc0\u63d0\u9ad8\u4e86\u7cbe\u78ba\u5ea6\uff0c\u65e8\u5728\u5f15\u767c ATP \u5371\u6a5f\u4e26\u524a\u5f31\u764c\u7d30\u80de\u3002\u6587\u4ef6\u8072\u7a31\u816b\u7624\u8461\u8404\u7cd6\u651d\u53d6\u6e1b\u5c11\u4e86 82%\uff0c\u8840\u6f3f\u9ea9\u91af\u80fa\u9178\u6e1b\u5c11\u4e86 79%\uff0c\u819c\u78f7\u8102\u5408\u6210\u6e1b\u5c11\u4e86 91%\u3002<\/p>\n<p><strong>\u79d1\u5b78\u4f9d\u64da<\/strong>\uff1a\u7814\u7a76\uff0c\u4f8b\u5982 <a href=\"https:\/\/www.nature.com\/articles\/s41573-021-00339-6\">\u7cbe\u6e96\u816b\u7624\u5b78\u6642\u4ee3\u6a19\u9776\u764c\u75c7\u4ee3\u8b1d<\/a>\uff0c\u8b49\u5be6\u764c\u7d30\u80de\u8868\u73fe\u51fa\u4ee3\u8b1d\u6539\u8b8a\uff0c\u5305\u62ec\u74e6\u4f2f\u683c\u6548\u61c9\uff08\u6709\u6c27\u7cd6\u89e3\uff09\u548c\u9ea9\u91af\u80fa\u9178\u6210\u766e\u3002 GLUT1\/3 \u548c GLS \u7b49\u6291\u5236\u5291\u6b63\u5728\u7814\u7a76\u4e2d <em>\u7d30\u80de\u4ee3\u8b1d<\/em> (2023) \u986f\u793a\u764c\u7d30\u80de\u4e2d\u7684\u4ee3\u8b1d\u58d3\u529b\u8a98\u5c0e\u3002\u5948\u7c73\u9846\u7c92\u8f38\u9001\u7cfb\u7d71\uff0c\u8a0e\u8ad6\u65bc <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2590183420300028\">\u764c\u75c7\u6cbb\u7642\u4e2d\u57fa\u65bc\u5948\u7c73\u9846\u7c92\u7684\u85e5\u7269\u8f38\u9001<\/a>\uff0c\u589e\u5f37\u7279\u7570\u6027\uff0c\u5118\u7ba1\u816b\u7624\u7570\u8cea\u6027\u548c\u812b\u9776\u6548\u61c9\u7b49\u6311\u6230\u4ecd\u7136\u5b58\u5728\u3002<\/p>\n<p><strong>\u81e8\u5e8a\u8b49\u64da\u8207\u6311\u6230<\/strong>\uff1a\u6240\u8072\u7a31\u7684\u81e8\u5e8a\u76ca\u8655\u8207\u65b0\u8208\u8a66\u9a57\u4e00\u81f4\uff0c\u4f46\u764c\u75c7\u985e\u578b\uff08\u4f8b\u5982\u80ba\u764c\u8207\u4e73\u764c\uff09\u548c\u60a3\u8005\u53cd\u61c9\u7684\u5dee\u7570\u8868\u660e\u9700\u8981\u500b\u6027\u5316\u7684\u65b9\u6cd5\u3002 2024\u5e74 <em>\u7d30\u80de<\/em> \u6587\u4ef6\u4e2d\u5f15\u7528\u7684\u7814\u7a76\u8072\u7a31\u6297\u85e5\u6027\u57fa\u56e0\u8868\u73fe\u6e1b\u5c11\u4e86 80%\uff0c\u9700\u8981\u900f\u904e\u66f4\u5927\u898f\u6a21\u7684\u591a\u4e2d\u5fc3\u8a66\u9a57\u9032\u884c\u9a57\u8b49\u3002\u502b\u7406\u65b9\u9762\u7684\u8003\u616e\uff0c\u4f8b\u5982\u7372\u53d6\u548c\u8ca0\u64d4\u80fd\u529b\uff0c\u5728 <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2949723X23000533\">\u57fa\u65bc\u5948\u7c73\u9846\u7c92\u7684\u85e5\u7269\u50b3\u8f38\u7cfb\u7d71\u7684\u529f\u6548\u56de\u9867<\/a>.<\/p>\n<h3>\u7bc0\u5f8b\u6027\u816b\u7624\u63a7\u5236<\/h3>\n<p><strong>\u7e3d\u7d50\u8207\u6a5f\u5236<\/strong>\uff1a\u6b64\u65b9\u6cd5\u4f7f\u7528\u4f4e\u5291\u91cf\u3001\u7bc0\u5f8b\u5316\u7642\uff08\u50b3\u7d71\u5291\u91cf\u7684 1\/10\uff09\u548c\u8840\u7ba1\u6b63\u5e38\u5316\u56e0\u5b50\u4f86\u63a7\u5236\u816b\u7624\u751f\u9577\uff0c\u964d\u4f4e\u6bd2\u6027\u4e26\u5be6\u73fe 67% \u7684\u5bb6\u5ead\u6cbb\u7642\u3002\u64da\u8072\u7a31\uff0c\u5b83\u5c07\u7121\u60e1\u5316\u5b58\u6d3b\u671f\u5f9e 5.2 \u500b\u6708\u5ef6\u9577\u81f3 11.8 \u500b\u6708\uff0c\u4e26\u5c07\u56b4\u91cd\u6bd2\u6027\u964d\u4f4e 67%\u3002<\/p>\n<p><strong>\u79d1\u5b78\u4f9d\u64da<\/strong>\uff1a\u4f4e\u5291\u91cf\u7bc0\u5f8b\u5316\u7642\u5df2\u88ab\u5ee3\u6cdb\u63a5\u53d7\uff0c\u5982 <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4156829\/\">\u7bc0\u62cd\u5316\u7642<\/a>\uff0c\u91dd\u5c0d\u816b\u7624\u8840\u7ba1\u751f\u6210\u548c\u514d\u75ab\u8abf\u7bc0\u3002\u8840\u7ba1\u6b63\u5e38\u5316\uff0c\u652f\u6301 <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2405844024007011\">\u7bc0\u62cd\u5316\u7642\u548c\u85e5\u7269\u518d\u5229\u7528<\/a>\uff0c\u900f\u904e\u589e\u5f37\u8840\u7ba1\u529f\u80fd\u4f86\u6539\u5584\u85e5\u7269\u8f38\u9001\u3002\u7814\u7a76\u5982 <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0959804913005418\">\u4f4e\u5291\u91cf\u7bc0\u62cd\u5316\u7642\uff1a\u7cfb\u7d71\u6027\u6587\u737b\u5206\u6790<\/a> \u78ba\u8a8d\u6e1b\u5c11\u7684\u526f\u4f5c\u7528\u548c\u6f5b\u5728\u7684\u6210\u672c\u6548\u76ca\uff0c\u7279\u5225\u662f\u5728\u4f4e\u6536\u5165\u74b0\u5883\u4e2d\u3002<\/p>\n<p><strong>\u81e8\u5e8a\u8b49\u64da\u8207\u6311\u6230<\/strong>\uff1a\u8072\u7a31\u7684\u76ca\u8655\u8207\u8f49\u79fb\u6027\u4e73\u764c\u7684\u81e8\u5e8a\u6578\u64da\u4e00\u81f4\uff0c\u4f46\u7642\u6548\u53ef\u80fd\u56e0\u816b\u7624\u985e\u578b\u548c\u60a3\u8005\u5065\u5eb7\u72c0\u6cc1\u800c\u7570\u3002\u5bb6\u5ead\u6cbb\u7642\u6a21\u5f0f\u96d6\u7136\u6709\u5e0c\u671b\uff0c\u4f46\u9700\u8981\u5805\u6301\u548c\u76e3\u6e2c\uff0c\u5982 <a href=\"https:\/\/www.lifespringcancercenter.com\/our-treatment\/low-dose-metronomic-chemotherapy\">\u751f\u547d\u6cc9\u764c\u75c7\u6cbb\u7642\u4e2d\u5fc3<\/a>\u3002\u95dc\u65bc\u6297\u85e5\u6027\u548c\u751f\u6d3b\u54c1\u8cea\u7684\u9577\u671f\u6578\u64da\u9700\u8981\u9032\u4e00\u6b65\u63a2\u7d22\u3002<\/p>\n<h3>\u57fa\u56e0\u6a19\u9776\u65ac\u9996<\/h3>\n<p><strong>\u7e3d\u7d50\u8207\u6a5f\u5236<\/strong>\uff1a\u6b64\u65b9\u6cd5\u4f7f\u7528\u6db2\u9ad4\u6d3b\u6aa2\u4f86\u6aa2\u6e2c 487 \u500b\u764c\u75c7\u9a45\u52d5\u57fa\u56e0\uff0c\u4e26\u4f7f\u7528\u5948\u7c73\u9846\u7c92\u905e\u9001\u7cfb\u7d71\u4f86\u9776\u5411 KRAS\u3001BRAF \u548c TP53 \u7b49\u7a81\u8b8a\uff0c\u5f9e\u800c\u514b\u670d\u8840\u8166\u5c4f\u969c\u7b49\u969c\u7919\u3002\u5b83\u8072\u7a31 ORR \u63d0\u9ad8\u4e86 67%\uff0c\u905e\u9001\u6548\u7387\u63d0\u9ad8\u4e86 9 \u500d\uff0c\u7279\u5225\u662f\u5c0d\u65bc\u8f49\u79fb\u7624\u3002<\/p>\n<p><strong>\u79d1\u5b78\u4f9d\u64da<\/strong>\uff1a\u5948\u7c73\u9846\u7c92\u8f38\u9001\u662f\u4e00\u500b\u524d\u6cbf\u9818\u57df\uff0c <a href=\"https:\/\/www.cancer.gov\/nano\/cancer-nanotechnology\/treatment\">\u5948\u7c73\u6280\u8853\u764c\u75c7\u6cbb\u7642\u548c\u6cbb\u7642<\/a> \u5f37\u8abf\u5176\u7a7f\u900f\u751f\u7406\u5c4f\u969c\u7684\u80fd\u529b\u3002\u6db2\u9ad4\u6d3b\u6aa2\uff0c\u8a0e\u8ad6\u65bc <a href=\"https:\/\/jnanobiotechnology.biomedcentral.com\/articles\/10.1186\/s12951-025-03433-8\">\u63a8\u9032\u764c\u75c7\u57fa\u56e0\u6cbb\u7642<\/a>\uff0c\u5be6\u73fe\u5373\u6642\u7a81\u8b8a\u6aa2\u6e2c\uff0c\u8207\u7cbe\u6e96\u816b\u7624\u5b78\u8da8\u52e2\u4fdd\u6301\u4e00\u81f4\u3002\u7814\u7a76\u65bc <a href=\"https:\/\/www.nature.com\/articles\/s41392-023-01642-x\">\u7528\u65bc\u764c\u75c7\u6cbb\u7642\u7684\u667a\u6167\u5948\u7c73\u9846\u7c92<\/a> \u5118\u7ba1\u6bd2\u6027\u548c\u9776\u5411\u7279\u7570\u6027\u7b49\u6311\u6230\u4ecd\u7136\u5b58\u5728\uff0c\u4f46\u5b83\u986f\u793a\u51fa\u6cbb\u7642\u8166\u8f49\u79fb\u7684\u5e0c\u671b\u3002<\/p>\n<p><strong>\u81e8\u5e8a\u8b49\u64da\u8207\u6311\u6230<\/strong>\uff1a\u8072\u7a31\u7684 ORR \u70ba 67% \u662f\u96c4\u5fc3\u52c3\u52c3\u7684\uff0c\u96d6\u7136\u65e9\u671f\u8a66\u9a57\u986f\u793a\u51fa\u5e0c\u671b\uff0c\u4f46\u9700\u8981\u66f4\u5927\u898f\u6a21\u7684\u7814\u7a76\u4f86\u9a57\u8b49\u8de8\u816b\u7624\u985e\u578b\u7684\u7642\u6548\u3002\u816b\u7624\u7570\u8cea\u6027\uff0c\u5982\u4e2d\u6240\u8ff0 <a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-023-01865-0\">\u9032\u6b65\u5948\u7c73\u6280\u8853\u4ee5\u6539\u5584\u6a19\u9776\u764c\u75c7\u6cbb\u7642<\/a>\uff0c\u53ef\u80fd\u6703\u9650\u88fd\u6210\u529f\uff0c\u9700\u8981\u7d44\u5408\u7b56\u7565\u3002<\/p>\n<h3>\u514d\u75ab\u98a8\u66b4\u6fc0\u6d3b<\/h3>\n<p><strong>\u7e3d\u7d50\u8207\u6a5f\u5236<\/strong>\uff1a\u6b64\u65b9\u6cd5\u4f7f\u7528 PD-1\/CTLA-4 \u6291\u5236\u5291\u3001\u65b0\u6297\u539f\u75ab\u82d7\u3001CAR-NK \u7d30\u80de\u548c\u5fae\u751f\u7269\u7d44\u8abf\u7bc0\u4f86\u6d3b\u5316\u591a\u5c64\u514d\u75ab\u53cd\u61c9\u3002\u5b83\u8072\u7a31 3 \u5e74\u5b58\u6d3b\u7387\u70ba 62.7%\uff08\u6539\u5584\u4e86 244%\uff09\uff0c\u5fa9\u767c\u7387\u964d\u4f4e\u4e86 85%\uff0c\u5c07\u300c\u51b7\u300d\u816b\u7624\u8f49\u8b8a\u70ba\u300c\u71b1\u300d\u816b\u7624\u3002<\/p>\n<p><strong>\u79d1\u5b78\u4f9d\u64da<\/strong>\uff1a\u806f\u5408\u514d\u75ab\u7642\u6cd5\u662f\u9818\u5148\u9818\u57df\uff0c <a href=\"https:\/\/jhoonline.biomedcentral.com\/articles\/10.1186\/s13045-021-01164-5\">\u6700\u5927\u5316\u764c\u75c7\u514d\u75ab\u6cbb\u7642\u76ca\u8655\u7684\u7d44\u5408\u7b56\u7565<\/a> \u986f\u793a\u51fa\u589e\u5f37\u7684\u53cd\u61c9\u3002\u6aa2\u67e5\u9ede\u6291\u5236\u5291\u3001\u65b0\u6297\u539f\u75ab\u82d7\u548c CAR-T\/NK \u7642\u6cd5\uff0c\u53c3\u898b <a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-025-02305-x\">\u764c\u75c7\u514d\u75ab\u6cbb\u7642\u7684\u9032\u5c55<\/a>\u3001\u63d0\u9ad8\u514d\u75ab\u8fa8\u8b58\u80fd\u529b\u3002\u5fae\u751f\u7269\u7d44\u8abf\u7bc0\uff0c\u7a81\u51fa\u986f\u793a\u65bc <a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-021-01316-8\">\u764c\u75c7\u4ee3\u8b1d\u91cd\u7de8\u7a0b\u548c\u514d\u75ab\u53cd\u61c9<\/a>\uff0c\u5f71\u97ff\u514d\u75ab\u6cbb\u7642\u7684\u7d50\u679c\uff0c\u5118\u7ba1\u5176\u4e00\u81f4\u6027\u6709\u722d\u8b70\u3002<\/p>\n<p><strong>\u81e8\u5e8a\u8b49\u64da\u8207\u6311\u6230<\/strong>\uff1a\u8072\u7a31\u7684\u751f\u5b58\u7387\u8207\u6700\u8fd1\u7684\u8a66\u9a57\u4e00\u81f4\uff0c\u4f46\u5be6\u9ad4\u7624\u7531\u65bc\u7570\u8cea\u6027\u548c\u514d\u75ab\u6291\u5236\u5fae\u74b0\u5883\u800c\u5e36\u4f86\u6311\u6230\uff0c\u5982 <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2772906024004989\">\u764c\u75c7\u514d\u75ab\u7642\u6cd5\u7684\u6700\u65b0\u9032\u5c55<\/a>\u3002\u95dc\u65bc\u5fa9\u767c\u548c\u514d\u75ab\u8a18\u61b6\u7684\u9577\u671f\u6578\u64da\u9700\u8981\u9032\u4e00\u6b65\u9a57\u8b49\u3002<\/p>\n<h3>\u6bd4\u8f03\u81e8\u5e8a\u7d50\u679c<\/h3>\n<p>\u9019\u4e9b\u6587\u4ef6\u63d0\u4f9b\u4e86\u4e00\u500b\u6bd4\u8f03\u50b3\u7d71\u7642\u6cd5\u548c\u56db\u7dad\u7642\u6cd5\u7684\u8868\u683c\uff0c\u70ba\u6e05\u695a\u8d77\u898b\uff0c\u5c07\u5176\u8907\u88fd\u5982\u4e0b\uff1a<\/p>\n<figure>\n<table class=\"has-fixed-layout\">\n<tbody>\n<tr>\n<td>\u6307\u6a19<\/td>\n<td>\u50b3\u7d71\u7684<br \/>\u6cbb\u7642<\/td>\n<td>\u56db\u7dad<br \/>\u6cbb\u7642<\/td>\n<td>\u6539\u9032<\/td>\n<\/tr>\n<tr>\n<td>\u5ba2\u89c0\u7de9\u89e3\u7387 (ORR)<\/td>\n<td>31%<\/td>\n<td>67%<\/td>\n<td>\u2191116%<\/td>\n<\/tr>\n<tr>\n<td>3 \u5e74\u5b58\u6d3b\u7387<\/td>\n<td>18%<\/td>\n<td>62.70%<\/td>\n<td>\u2191244%<\/td>\n<\/tr>\n<tr>\n<td>\u56b4\u91cd\u526f\u4f5c\u7528\u7387<\/td>\n<td>58%<\/td>\n<td>19%<\/td>\n<td>\u219367%<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/figure>\n<p>\u8868\u683c\u5f37\u8abf\u4e86\u8a72\u7642\u6cd5\u7684\u6f5b\u529b\uff0c\u4f46\u60a3\u8005\u7fa4\u9ad4\u548c\u816b\u7624\u985e\u578b\u4e4b\u9593\u7684\u5dee\u7570\u503c\u5f97\u9032\u4e00\u6b65\u7814\u7a76\u3002<\/p>\n<h2><strong>\u7d50\u8ad6<\/strong><\/h2>\n<p>\u56db\u7dad\u7121\u6bd2\u7642\u6cd5\u6574\u5408\u4e86\u89e3\u6c7a\u764c\u75c7\u8907\u96dc\u6027\u7684\u5c16\u7aef\u7b56\u7565\uff0c\u6bcf\u7a2e\u65b9\u6cd5\u90fd\u5f97\u5230\u65b0\u8208\u7814\u7a76\u7684\u652f\u6301\u3002\u7136\u800c\uff0c\u816b\u7624\u7570\u8cea\u6027\u3001\u81e8\u5e8a\u9a57\u8b49\u548c\u53ef\u8fd1\u6027\u7b49\u6311\u6230\u9700\u8981\u4e0d\u65b7\u63a2\u7d22\u3002\u5efa\u8b70\u7684\u53e3\u865f\u548c\u53e3\u865f\u65e8\u5728\u9ad4\u73fe\u8a72\u7642\u6cd5\u7684\u627f\u8afe\uff0c\u4e26\u5f15\u767c\u5c0d\u5176\u6539\u8b8a\u764c\u75c7\u6cbb\u7642\u6f5b\u529b\u7684\u9032\u4e00\u6b65\u8a0e\u8ad6\u3002<\/p>\n<h2>\u4e3b\u8981\u5f15\u6587<\/h2>\n<ul>\n<li><a href=\"https:\/\/www.nature.com\/articles\/s41573-021-00339-6\">\u7cbe\u6e96\u816b\u7624\u5b78\u6642\u4ee3\u6a19\u9776\u764c\u75c7\u4ee3\u8b1d<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2590183420300028\">\u764c\u75c7\u6cbb\u7642\u4e2d\u57fa\u65bc\u5948\u7c73\u9846\u7c92\u7684\u85e5\u7269\u8f38\u9001<\/a><\/li>\n<li><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4156829\/\">\u7bc0\u62cd\u5316\u7642<\/a><\/li>\n<li><a href=\"https:\/\/jnanobiotechnology.biomedcentral.com\/articles\/10.1186\/s12951-025-03433-8\">\u63a8\u9032\u764c\u75c7\u57fa\u56e0\u6cbb\u7642<\/a><\/li>\n<li><a href=\"https:\/\/jhoonline.biomedcentral.com\/articles\/10.1186\/s13045-021-01164-5\">\u6700\u5927\u5316\u764c\u75c7\u514d\u75ab\u6cbb\u7642\u76ca\u8655\u7684\u7d44\u5408\u7b56\u7565<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2772906024004989\">\u764c\u75c7\u514d\u75ab\u7642\u6cd5\u7684\u6700\u65b0\u9032\u5c55<\/a><\/li>\n<li><a href=\"https:\/\/www.cancer.gov\/nano\/cancer-nanotechnology\/treatment\">\u5948\u7c73\u6280\u8853\u764c\u75c7\u6cbb\u7642\u548c\u6cbb\u7642<\/a><\/li>\n<li><a href=\"https:\/\/www.nature.com\/articles\/s41392-023-01642-x\">\u7528\u65bc\u764c\u75c7\u6cbb\u7642\u7684\u667a\u6167\u5948\u7c73\u9846\u7c92<\/a><\/li>\n<li><a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-021-01316-8\">\u764c\u75c7\u4ee3\u8b1d\u91cd\u7de8\u7a0b\u548c\u514d\u75ab\u53cd\u61c9<\/a><\/li>\n<li><a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-025-02305-x\">\u764c\u75c7\u514d\u75ab\u6cbb\u7642\u7684\u9032\u5c55<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2405844024007011\">\u7bc0\u62cd\u5316\u7642\u548c\u85e5\u7269\u518d\u5229\u7528<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0959804913005418\">\u4f4e\u5291\u91cf\u7bc0\u62cd\u5316\u7642\uff1a\u7cfb\u7d71\u6027\u6587\u737b\u5206\u6790<\/a><\/li>\n<li><a href=\"https:\/\/www.lifespringcancer.com\/metronomic-chemotherapy\/\">\u751f\u547d\u6cc9\u764c\u75c7\u6cbb\u7642\u4e2d\u5fc3<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2772906024004989\">\u57fa\u65bc\u5948\u7c73\u9846\u7c92\u7684\u85e5\u7269\u50b3\u8f38\u7cfb\u7d71\u7684\u529f\u6548\u56de\u9867<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2772906024004989\">\u9032\u6b65\u5948\u7c73\u6280\u8853\u4ee5\u6539\u5584\u6a19\u9776\u764c\u75c7\u6cbb\u7642<\/a><\/li>\n<\/ul>\n<hr>\n<div class=\"ac-blog-cta\">\n<h2>\u9700\u8981\u5354\u52a9\u4e86\u89e3\u6cbb\u7642\u9078\u64c7\uff1f<\/h2>\n<p>\u6211\u5011\u7684\u60a3\u8005\u670d\u52d9\u5718\u968a\u53ef\u4ee5\u5e6b\u52a9\u60a8\u6e96\u5099\u5831\u544a\u4e26\u5b89\u6392\u9069\u7576\u7684\u5c08\u5bb6\u8aee\u8a62\u3002\u672c\u6587\u662f\u4e00\u822c\u8a0a\u606f\uff0c\u800c\u4e0d\u662f\u8a3a\u65b7\u3002<\/p>\n<p><a href=\"\/zh-hk\/appointment\/\">\u9810\u7d04\u8aee\u8a62<\/a> &nbsp;|&nbsp; <a href=\"\/zh-hk\/cancer\/\">\u63a2\u7d22\u6240\u6709\u764c\u75c7\u985e\u578b<\/a><\/p>\n<\/div>\n<p class=\"ac-blog-disclaimer\"><em>\u91ab\u7642\u514d\u8cac\u8072\u660e\uff1a\u672c\u6587\u50c5\u7528\u65bc\u4e00\u822c\u6559\u80b2\uff0c\u4e0d\u80fd\u53d6\u4ee3\u5408\u683c\u81e8\u5e8a\u91ab\u751f\u7684\u5efa\u8b70\u3002\u6cbb\u7642\u6c7a\u5b9a\u61c9\u57fa\u65bc\u500b\u4eba\u7684\u8a3a\u65b7\u3001\u5206\u671f\u3001\u75c5\u7406\u548c\u6574\u9ad4\u5065\u5eb7\u72c0\u6cc1\u3002\u5982\u679c\u60a8\u767c\u73fe\u6301\u7e8c\u6216\u4ee4\u4eba\u64d4\u6182\u7684\u75c7\u72c0\uff0c\u8acb\u5c0b\u6c42\u91ab\u7642\u8a55\u4f30\u3002<\/em><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Non-Small Cell Lung Cancer (NSCLC) represents approximately 85% of all lung cancers, profoundly impacting millions globally each year.<\/p>","protected":false},"featured_media":269,"menu_order":68,"template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-390","cancer_type","type-cancer_type","status-publish","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/all-cancers.com\/zh-hk\/wp-json\/wp\/v2\/cancer_type\/390","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/all-cancers.com\/zh-hk\/wp-json\/wp\/v2\/cancer_type"}],"about":[{"href":"https:\/\/all-cancers.com\/zh-hk\/wp-json\/wp\/v2\/types\/cancer_type"}],"version-history":[{"count":1,"href":"https:\/\/all-cancers.com\/zh-hk\/wp-json\/wp\/v2\/cancer_type\/390\/revisions"}],"predecessor-version":[{"id":530,"href":"https:\/\/all-cancers.com\/zh-hk\/wp-json\/wp\/v2\/cancer_type\/390\/revisions\/530"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/all-cancers.com\/zh-hk\/wp-json\/wp\/v2\/media\/269"}],"wp:attachment":[{"href":"https:\/\/all-cancers.com\/zh-hk\/wp-json\/wp\/v2\/media?parent=390"}],"curies":[{"name":"\u53ef\u6fd5\u6027\u7c89\u5291","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}