{"id":441,"date":"2026-02-24T09:00:00","date_gmt":"2026-02-24T09:00:00","guid":{"rendered":"https:\/\/all-cancers.com\/cancer\/myelodysplastic-syndromes-mds-cancer\/"},"modified":"2026-10-29T13:38:11","modified_gmt":"2026-10-29T13:38:11","slug":"myelodysplastic-syndromes-mds-cancer","status":"publish","type":"cancer_type","link":"https:\/\/all-cancers.com\/zh-hk\/cancer\/myelodysplastic-syndromes-mds-cancer\/","title":{"rendered":"\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u75c7\u5019\u7fa4 (MDS)"},"content":{"rendered":"<div class=\"ac-blog-article\">\n<p class=\"ac-blog-lead\"><strong>\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS) \u662f\u4e00\u7cfb\u5217\u7570\u8cea\u6027\u8840\u6db2\u75be\u75c5\uff0c\u5176\u7279\u5fb5\u662f\u9aa8\u9ad3\u4e2d\u7d30\u80de\u7e41\u6b96\u7570\u5e38\u3002\u9019\u4e9b\u60c5\u6cc1\u6703\u7834\u58de\u6b63\u5e38\u7684\u8840\u6db2\u751f\u6210\uff0c\u5c0e\u81f4\u5404\u7a2e\u8840\u7403\u6e1b\u5c11\u75c7\uff0c\u7279\u5225\u662f\u8ca7\u8840\u3001\u767d\u8840\u7403\u6e1b\u5c11\u75c7\u548c\u8840\u5c0f\u677f\u6e1b\u5c11\u75c7\u3002<\/strong><\/p>\n<nav class=\"ac-blog-toc\" aria-label=\"\u672c\u6587\u5c0e\u89bd\">\n<p><strong>\u672c\u6587\u5c0e\u89bd<\/strong><\/p>\n<ul>\n<li><a href=\"#what-is-myelodysplastic-syndromes-mds\">\u4ec0\u9ebc\u662f\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u75c7\u5019\u7fa4 (MDS)\uff1f<\/a><\/li>\n<li><a href=\"#causes-and-risk-factors-of-myelodysplastic-syndromes-mds\">\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS) \u7684\u539f\u56e0\u548c\u5371\u96aa\u56e0\u7d20<\/a><\/li>\n<li><a href=\"#symptoms-of-myelodysplastic-syndromes-mds\">\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u75c7\u5019\u7fa4 (MDS) \u7684\u75c7\u72c0<\/a><\/li>\n<li><a href=\"#stages-of-myelodysplastic-syndromes-mds-and-survival-rates\">\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS) \u7684\u968e\u6bb5\u548c\u5b58\u6d3b\u7387<\/a><\/li>\n<li><a href=\"#treatment-options-for-myelodysplastic-syndromes-mds\">\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS) \u7684\u6cbb\u7642\u9078\u64c7<\/a><\/li>\n<li><a href=\"#limitations-of-traditional-therapies-for-myelodysplastic-syndromes-mds\">\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS) \u50b3\u7d71\u7642\u6cd5\u7684\u5c40\u9650\u6027<\/a><\/li>\n<li><a href=\"#conclusion\">\u7d50\u8ad6<\/a><\/li>\n<\/ul>\n<\/nav>\n<h2 id=\"what-is-myelodysplastic-syndromes-mds\">\u4ec0\u9ebc\u662f\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u75c7\u5019\u7fa4 (MDS)\uff1f<\/h2>\n<p>\u4e86\u89e3\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS) \u9996\u5148\u8981\u4e86\u89e3\u5176\u751f\u7269\u5b78\u57fa\u790e\u3002 MDS \u6d89\u53ca\u9020\u8840\u5e79\u7d30\u80de\u589e\u751f\u5931\u63a7\u3001\u5206\u5316\u53d7\u640d\u548c\u51cb\u4ea1\u589e\u52a0\u3002\u8207\u8840\u7403\u6b63\u5e38\u6210\u719f\u7684\u5065\u5eb7\u9020\u8840\u7cfb\u7d71\u4e0d\u540c\uff0c\u53d7MDS\u5f71\u97ff\u7684\u7d30\u80de\u7121\u6cd5\u6b63\u5e38\u6210\u719f\uff0c\u5e38\u5e38\u9677\u5165\u4e0d\u6210\u719f\u968e\u6bb5\u4e26\u5931\u53bb\u529f\u80fd\u3002\u56e0\u6b64\uff0c\u60a3\u8005\u7d93\u5e38\u60a3\u6709\u6162\u6027\u8ca7\u8840\uff0c\u4e26\u4e14\u66f4\u5bb9\u6613\u767c\u751f\u611f\u67d3\u548c\u51fa\u8840\u3002<\/p>\n<p>\u5728\u4ee3\u8b1d\u6c34\u5e73\u4e0a\uff0cMDS \u4e2d\u767c\u73fe\u7684\u764c\u7d30\u80de\u8868\u73fe\u51fa\u7368\u7279\u7684\u8106\u5f31\u6027\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u9019\u4e9b\u60e1\u6027\u7d30\u80de\u8868\u73fe\u51fa\u74e6\u4f2f\u683c\u6548\u61c9\uff1a\u5373\u4f7f\u5728\u6c27\u6c23\u5145\u8db3\u7684\u60c5\u6cc1\u4e0b\uff0c\u5c0d\u7cd6\u89e3\u4f5c\u7528\u7684\u4f9d\u8cf4\u4e5f\u6703\u589e\u52a0\u3002\u9019\u7a2e\u4e0d\u898f\u5247\u7684\u4ee3\u8b1d\u5c0e\u81f4\u764c\u7d30\u80de\u6d88\u8017\u8461\u8404\u7cd6\u7684\u901f\u5ea6\u6bd4\u5065\u5eb7\u7d30\u80de\u5feb\u7d04 200 \u500d\uff0c\u4f7f\u81e8\u5e8a\u91ab\u751f\u80fd\u5920\u900f\u904e\u5275\u65b0\u7684\u4ee3\u8b1d\u7642\u6cd5\u4f86\u5229\u7528\u9019\u4e00\u7279\u6027\u3002<\/p>\n<p>\u5728\u5168\u7403\u7bc4\u570d\u5167\uff0c\u4f30\u8a08\u6bcf\u5e74\u8a3a\u65b7\u51fa\u8fd1 10 \u842c\u4f8b\u65b0\u7684\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u75c7\u5019\u7fa4 (MDS) \u75c5\u4f8b\uff08\u4e16\u754c\u885b\u751f\u7d44\u7e54\uff0c2024 \u5e74\uff09\u3002\u96d6\u7136\u76f8\u5c0d\u7f55\u898b\uff0c\u4f46\u5176\u76db\u884c\u7387\u96a8\u8457\u5e74\u9f61\u7684\u589e\u9577\u800c\u986f\u8457\u589e\u52a0\uff0c\u5c24\u5176\u662f\u5728 60 \u6b72\u4ee5\u5f8c\u3002\u7279\u5225\u662f\u5728\u9999\u6e2f\uff0c\u9999\u6e2f\u764c\u75c7\u767b\u8a18\u8655\uff082025 \u5e74\uff09\u7684\u6578\u64da\u8868\u660e\uff0c\u6bcf\u5e74\u5927\u7d04\u51fa\u73fe 400 \u4f8b\u65b0\u7684 MDS \u75c5\u4f8b\uff0c\u4e3b\u8981\u767c\u751f\u5728 65 \u6b72\u4ee5\u4e0a\u7684\u500b\u9ad4\u4e2d\u3002<\/p>\n<h3 id=\"population-affected-and-epidemiology-in-asia\">\u4e9e\u6d32\u53d7\u5f71\u97ff\u4eba\u53e3\u548c\u6d41\u884c\u75c5\u5b78<\/h3>\n<p>\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u75c7\u5019\u7fa4\u4e3b\u8981\u5f71\u97ff\u8001\u5e74\u65cf\u7fa4\uff0c\u60a3\u8005\u8a3a\u65b7\u6642\u7684\u4e2d\u4f4d\u5e74\u9f61\u63a5\u8fd1 70 \u6b72\u3002\u5f9e\u6027\u5225\u4f86\u770b\uff0c\u7537\u6027\u767c\u751f\u7387\u7565\u9ad8\uff0c\u7d04 1.5 \u540d\u7537\u6027\u60a3\u8005\u5c0d\u61c9 1 \u540d\u5973\u6027\u60a3\u8005\u3002\u907a\u50b3\u548c\u74b0\u5883\u56e0\u7d20\u6975\u5927\u5730\u5f71\u97ff\u4e86\u4e9e\u6d32\u4eba\u7fa4\u7684\u5730\u7406\u5dee\u7570\uff0c\u6d41\u884c\u75c5\u5b78\u7814\u7a76\u5f37\u8abf\u4e86\u4e9e\u6d32\u5730\u5340\u767c\u75c5\u7387\u548c\u4e9e\u578b\u6bd4\u4f8b\u7684\u5dee\u7570\u3002<\/p>\n<p>\u5728\u4e9e\u6d32\u4eba\u7fa4\u4e2d\uff0c\u65e2\u5f80\u5316\u7642\u6216\u653e\u7642\u3001\u74b0\u5883\u6bd2\u7d20\u66b4\u9732\u4ee5\u53ca\u67d0\u4e9b\u907a\u50b3\u50be\u5411\u7b49\u56e0\u7d20\u6703\u986f\u8457\u589e\u52a0MDS\u98a8\u96aa\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u9999\u6e2f\u548c\u5176\u4ed6\u4e9e\u6d32\u5df2\u958b\u767c\u5730\u5340\u7684\u767c\u75c5\u7387\u76f8\u5c0d\u8f03\u9ad8\uff0c\u90e8\u5206\u8207\u58fd\u547d\u5ef6\u9577\u3001\u74b0\u5883\u58d3\u529b\u3001\u57ce\u5e02\u5de5\u696d\u5316\u548c\u4eba\u53e3\u8001\u5316\u6709\u95dc\u3002<\/p>\n<h3 id=\"emotional-and-physical-impact-on-patients\">\u5c0d\u60a3\u8005\u60c5\u7dd2\u548c\u8eab\u9ad4\u7684\u5f71\u97ff<\/h3>\n<p>\u9762\u81e8\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7\u8a3a\u65b7\u7684\u500b\u4eba\u901a\u5e38\u6703\u7d93\u6b77\u56b4\u91cd\u7684\u60c5\u7dd2\u58d3\u529b\u548c\u8eab\u9ad4\u9650\u5236\u3002\u56b4\u91cd\u75b2\u52de\u3001\u53cd\u8986\u611f\u67d3\u3001\u5bb9\u6613\u7600\u9752\u3001\u547c\u5438\u56f0\u96e3\u548c\u983b\u7e41\u51fa\u8840\u7b49\u5e38\u898b\u75c7\u72c0\u56b4\u91cd\u5f71\u97ff\u751f\u6d3b\u54c1\u8cea\u3002\u5fc3\u7406\u5065\u5eb7\u554f\u984c\uff0c\u7279\u5225\u662f\u7126\u616e\u548c\u6182\u9b31\uff0c\u7d93\u5e38\u4f34\u96a8\u8457\u8eab\u9ad4\u8868\u73fe\uff0c\u5f37\u8abf\u4e86\u5bcc\u6709\u540c\u60c5\u5fc3\u7684\u591a\u5b78\u79d1\u60a3\u8005\u8b77\u7406\u7684\u5fc5\u8981\u6027\u3002<\/p>\n<ul>\n<li>\u8ca7\u8840\u5f15\u8d77\u7684\u75b2\u52de\u6703\u56b4\u91cd\u5f71\u97ff\u65e5\u5e38\u6d3b\u52d5\u91cf\u3002<\/li>\n<li>\u51fa\u8840\u554f\u984c\uff0c\u5f9e\u8f15\u5fae\u7684\u7600\u50b7\u5230\u56b4\u91cd\u7684\u767c\u4f5c\uff0c\u90fd\u6703\u5f15\u8d77\u4eba\u5011\u5c0d\u65e5\u5e38\u751f\u6d3b\u4efb\u52d9\u7684\u7126\u616e\u3002<\/li>\n<li>\u7531\u65bc\u767d\u8840\u7403\u8a08\u6578\u964d\u4f4e\u800c\u983b\u7e41\u767c\u751f\u611f\u67d3\uff0c\u9032\u4e00\u6b65\u9650\u5236\u4e86\u60a3\u8005\u7684\u6d3b\u52d5\u6027\u4e26\u6e1b\u5c11\u4e86\u793e\u5340\u548c\u793e\u6703\u53c3\u8207\u3002<\/li>\n<\/ul>\n<p>\u70ba\u4e86\u61c9\u5c0d\u9019\u4e9b\u6311\u6230\uff0cAllCancer \u7684\u9999\u6e2f\u4ee3\u8b1d\u7642\u6cd5\u5f15\u5165\u4e86\u91dd\u5c0d\u764c\u7d30\u80de\u4ee3\u8b1d\u8106\u5f31\u6027\u7684\u9769\u547d\u6027\u65b9\u6cd5\u3002\u6709\u95dc\u8a73\u7d30\u7684\u6cbb\u7642\u65b9\u6cd5\uff0c\u8acb\u63a2\u7d22\u6211\u5011\u5c08\u9580\u7684\u764c\u75c7\u751f\u7269\u5b78\u6559\u80b2\u9801\u9762\u548c\u4ee3\u8b1d\u816b\u7624\u5b78\u5275\u65b0\u3002<\/p>\n<h2 id=\"causes-and-risk-factors-of-myelodysplastic-syndromes-mds\">\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS) \u7684\u539f\u56e0\u548c\u5371\u96aa\u56e0\u7d20<\/h2>\n<p>\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7\u7684\u78ba\u5207\u75c5\u56e0\u4ecd\u7136\u662f\u591a\u65b9\u9762\u7684\uff0c\u5305\u62ec\u907a\u50b3\u3001\u74b0\u5883\u548c\u751f\u6d3b\u65b9\u5f0f\u7684\u5f71\u97ff\u3002\u6709\u6548\u8b58\u5225\u9019\u4e9b\u56e0\u7d20\u6709\u52a9\u65bc\u9810\u9632\u548c\u65e9\u671f\u5e79\u9810\uff0c\u662f\u60a3\u8005\u6cbb\u7642\u7d50\u679c\u4e0d\u53ef\u6216\u7f3a\u7684\u4e00\u90e8\u5206\u3002<\/p>\n<h3 id=\"genetic-and-molecular-factors\">\u907a\u50b3\u548c\u5206\u5b50\u56e0\u7d20<\/h3>\n<p>\u907a\u50b3\u7570\u5e38\u662fMDS\u767c\u5c55\u7684\u6838\u5fc3\u3002\u5178\u578b\u7684\u5206\u5b50\u7578\u8b8a\u5305\u62ec\u67d3\u8272\u9ad4\u7f3a\u5931\u3001\u91cd\u8907\u6216\u6613\u4f4d\u3002\u81f3\u95dc\u91cd\u8981\u7684\u662f\uff0c\u6d89\u53ca TET2\u3001SF3B1\u3001ASXL1\u3001TP53 \u548c RUNX1 \u7b49\u57fa\u56e0\u7684\u7a81\u8b8a\u983b\u7e41\u51fa\u73fe\u5728\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7\u60a3\u8005\u4e2d\u3002\u9019\u4e9b\u7a81\u8b8a\u986f\u8457\u5c0e\u81f4\u7d30\u80de\u5206\u5316\u53d7\u640d\u548c\u7d30\u80de\u51cb\u4ea1\u589e\u5f37\u3002<\/p>\n<ul>\n<li>SF3B1 \u7a81\u8b8a\u662f\u74b0\u5f62\u9435\u7c92\u5e7c\u7d30\u80de\u4e9e\u578b\u60a3\u8005\u7684\u7279\u5fb5\u3002<\/li>\n<li>TP53 \u7a81\u8b8a\u8207\u56b4\u91cd\u7684\u6297\u85e5\u6027\u75be\u75c5\u8868\u578b\u6709\u95dc\u3002<\/li>\n<li>ASXL1 \u57fa\u56e0\u7a81\u8b8a\u5177\u6709\u4e0d\u826f\u9810\u5f8c\u610f\u7fa9\u3002<\/li>\n<\/ul>\n<h3 id=\"environmental-factors\">\u74b0\u5883\u56e0\u7d20<\/h3>\n<p>\u63a5\u89f8\u6709\u6bd2\u7269\u8cea\u6703\u986f\u8457\u589e\u52a0 MDS \u98a8\u96aa\u3002\u5148\u524d\u6d89\u53ca\u5316\u7642\u6216\u653e\u7642\u7684\u6cbb\u7642\u6703\u5e36\u4f86\u5f88\u5927\u7684\u98a8\u96aa\uff0c\u53cd\u6620\u51fa\u7e7c\u767c\u6027\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u75c7\u5019\u7fa4\uff08MDS\uff09\u7684\u589e\u52a0\u3002\u6b64\u5916\uff0c\u9577\u671f\u63a5\u89f8\u74b0\u5883\u81f4\u764c\u7269\uff08\u5305\u62ec\u82ef\u548c\u91cd\u91d1\u5c6c\uff09\u662fMDS\u7b49\u8840\u6db2\u60e1\u6027\u816b\u7624\u7684\u4e00\u500b\u76f8\u7576\u5927\u7684\u5371\u96aa\u56e0\u5b50\u3002<\/p>\n<h3 id=\"lifestyle-factors-and-prevention\">\u751f\u6d3b\u65b9\u5f0f\u56e0\u7d20\u53ca\u9810\u9632<\/h3>\n<p>\u5118\u7ba1\u8207\u907a\u50b3\u6216\u74b0\u5883\u5f71\u97ff\u76f8\u6bd4\uff0c\u98f2\u98df\u548c\u98f2\u9152\u7b49\u751f\u6d3b\u65b9\u5f0f\u56e0\u7d20\u7684\u4f5c\u7528\u4e0d\u592a\u660e\u78ba\uff0c\u4f46\u4fdd\u6301\u5065\u5eb7\u7684\u751f\u6d3b\u65b9\u5f0f\u53ef\u4ee5\u5927\u5927\u964d\u4f4e\u6574\u9ad4\u764c\u75c7\u548c\u8840\u6db2\u75be\u75c5\u7684\u98a8\u96aa\u3002\u6700\u8fd1\uff0c\u79d1\u5b78\u7814\u7a76\u63a2\u7d22\u4e86\u764c\u7d30\u80de\u7368\u7279\u7684\u4ee3\u8b1d\u8106\u5f31\u6027\uff0c\u5305\u62ec\u8461\u8404\u7cd6\u548c\u9ea9\u91af\u80fa\u9178\u4f9d\u8cf4\u6027\uff0c\u70ba\u65b0\u7684\u9810\u9632\u7b56\u7565\u548c\u6a19\u9776\u6cbb\u7642\u92ea\u5e73\u4e86\u9053\u8def\u3002<\/p>\n<ul>\n<li>\u512a\u5316\u71df\u990a\u548c\u5b9a\u671f\u9032\u884c\u9ad4\u80b2\u6d3b\u52d5\u53ef\u4ee5\u6700\u5927\u9650\u5ea6\u5730\u6e1b\u5c11\u6c27\u5316\u58d3\u529b\u548c\u767c\u708e\u3002<\/li>\n<li>\u907f\u514d\u5438\u7159\u548c\u904e\u91cf\u98f2\u9152\u53ef\u4ee5\u986f\u8457\u964d\u4f4e\u764c\u75c7\u98a8\u96aa\u3002<\/li>\n<li>\u91dd\u5c0d\u74e6\u723e\u5821\u6548\u61c9\u548c\u9ea9\u91af\u80fa\u9178\u6210\u766e\u7684\u4ee3\u8b1d\u7642\u6cd5\u986f\u793a\u51fa\u826f\u597d\u7684\u9810\u9632\u548c\u6cbb\u7642\u6f5b\u529b\uff0c\u7279\u5225\u662f\u8207\u9999\u6e2f AllCancer \u63a1\u7528\u7684\u4ee3\u8b1d\u816b\u7624\u6cbb\u7642\u5275\u65b0\u76f8\u95dc\u3002<\/li>\n<\/ul>\n<h3 id=\"asian-specific-risk-factors-and-hong-kong-trends\">\u4e9e\u6d32\u7279\u6709\u7684\u98a8\u96aa\u56e0\u7d20\u548c\u9999\u6e2f\u8da8\u52e2<\/h3>\n<p>\u5340\u57df\u5206\u6790\u986f\u793a\u4e9e\u6d32\u4eba\u7fa4\u4e2d\u7a81\u51fa\u7684\u7279\u5b9a\u5371\u96aa\u56e0\u5b50\u3002\u9999\u6e2f\u7684\u4eba\u53e3\u8001\u5316\u3001\u5de5\u696d\u6210\u9577\u5c0e\u81f4\u7684\u82ef\u66b4\u9732\u6d41\u884c\u4ee5\u53ca\u5316\u7642\u5f15\u8d77\u7684\u7e7c\u767c\u6027\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7\u75c5\u4f8b\u7684\u767c\u751f\u7387\u8f03\u9ad8\uff0c\u5c0d\u5340\u57df\u6d41\u884c\u75c5\u5b78\u7522\u751f\u4e86\u91cd\u5927\u5f71\u97ff\u3002<\/p>\n<p>\u53ca\u6642\u7be9\u6aa2\u548c\u65e9\u671f\u6aa2\u6e2c\u5c0d\u65bc\u4e9e\u6d32\u60a3\u8005\u7684\u826f\u597d\u9810\u5f8c\u4ecd\u7136\u81f3\u95dc\u91cd\u8981\uff0c\u53ef\u4ee5\u986f\u8457\u63d0\u9ad8\u5b58\u6d3b\u7387\u4e26\u6e1b\u5c11\u8907\u96dc\u7684\u9032\u5c55\u3002\u63a2\u7d22 AllCancer \u7684\u5168\u9762\u7be9\u6aa2\u548c\u8a3a\u65b7\u670d\u52d9\uff0c\u91dd\u5c0d\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS) \u9032\u884c\u4e3b\u52d5\u5065\u5eb7\u7ba1\u7406\u3002<\/p>\n<p>\u82e5\u8981\u9032\u4e00\u6b65\u4e86\u89e3 MDS \u98a8\u96aa\uff0c\u8acb\u65b0\u589e\u503c\u5f97\u4fe1\u8cf4\u7684\u5916\u90e8\u91ab\u7642\u8cc7\u6e90\uff0c\u4f8b\u5982\u4e16\u754c\u885b\u751f\u7d44\u7e54\u764c\u75c7\u7814\u7a76\u4e2d\u5fc3\u3001\u9999\u6e2f\u764c\u75c7\u767b\u8a18\u8655\u548c\u7f8e\u570b\u570b\u5bb6\u764c\u75c7\u7814\u7a76\u6240\uff0c\u6216\u806f\u7d61\u6211\u5011\u7684\u4ee3\u8b1d\u816b\u7624\u5b78\u5c08\u5bb6\u4ee5\u7372\u5f97\u8a73\u7d30\u8aee\u8a62\u548c\u65e9\u671f\u7be9\u6aa2\u5efa\u8b70\u3002<\/p>\n<h2 id=\"symptoms-of-myelodysplastic-syndromes-mds\">\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u75c7\u5019\u7fa4 (MDS) \u7684\u75c7\u72c0<\/h2>\n<p>\u53ca\u65e9\u8b58\u5225\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS) \u75c7\u72c0\u53ef\u986f\u8457\u6539\u5584\u6cbb\u7642\u7d50\u679c\u548c\u6574\u9ad4\u9810\u5f8c\u3002\u75c7\u72c0\u56e0\u75be\u75c5\u968e\u6bb5\u4ee5\u53ca\u60a3\u8005\u500b\u5225\u7279\u5fb5\u800c\u7570\u3002\u5982\u679c\u60a8\u767c\u73fe\u4ee5\u4e0b\u4efb\u4f55\u75c7\u72c0\uff0c\u8acb\u7acb\u5373\u5c0b\u6c42\u91ab\u7642\u8a55\u4f30\uff0c\u9019\u4e00\u9ede\u81f3\u95dc\u91cd\u8981\u3002<\/p>\n<ul>\n<li><strong>\u75b2\u52de\u548c\u865b\u5f31\uff1a<\/strong> \u6301\u7e8c\u75b2\u52de\u662f\u7531\u65bc\u8ca7\u8840\u76f8\u95dc\u7684\u6c27\u6c23\u8f38\u9001\u80fd\u529b\u964d\u4f4e\u800c\u6700\u65e9\u51fa\u73fe\u7684\u6307\u6a19\u4e4b\u4e00\u3002<\/li>\n<li><strong>\u547c\u5438\u6025\u4fc3:<\/strong> \u8840\u7403\u751f\u6210\u7121\u6548\u5c0e\u81f4\u8840\u7d05\u7d20\u6c34\u5e73\u964d\u4f4e\uff0c\u53ef\u80fd\u5c0e\u81f4\u547c\u5438\u56f0\u96e3\uff0c\u5c24\u5176\u662f\u5728\u9ad4\u529b\u6d3b\u52d5\u671f\u9593\u3002<\/li>\n<li><strong>\u76ae\u819a\u84bc\u767d\u6216\u984f\u8272\u7570\u5e38\uff1a<\/strong> \u7d05\u8840\u7403\u6578\u6e1b\u5c11\u6703\u5c0e\u81f4\u76ae\u819a\u84bc\u767d\u6216\u7532\u5e8a\u6216\u9ecf\u819c\u7570\u5e38\u8b8a\u8272\u3002<\/li>\n<li><strong>\u983b\u7e41\u611f\u67d3\uff1a<\/strong> \u7531\u65bc\u5faa\u74b0\u4e2d\u7684\u4e2d\u6027\u7c92\u7d30\u80de\u6e1b\u5c11\uff0c\u60a3\u8005\u66f4\u5bb9\u6613\u51fa\u73fe\u547c\u5438\u9053\u611f\u67d3\u3001\u6ccc\u5c3f\u9053\u611f\u67d3\u6216\u76ae\u819a\u611f\u67d3\u3002<\/li>\n<li><strong>\u5bb9\u6613\u7600\u9752\u6216\u51fa\u8840\uff1a<\/strong> \u8840\u5c0f\u677f\u8a08\u6578\u4f4e\uff08\u8840\u5c0f\u677f\u6e1b\u5c11\u75c7\uff09\u6703\u5c0e\u81f4\u81ea\u767c\u6027\u6216\u8f15\u50b7\u5f8c\u51fa\u73fe\u7600\u50b7\u6216\u7600\u9ede\u3002<\/li>\n<li><strong>\u767c\u71d2:<\/strong> \u53cd\u8986\u6216\u4e0d\u660e\u539f\u56e0\u7684\u767c\u71d2\u53ef\u80fd\u8868\u793a\u6f5b\u5728\u7684\u611f\u67d3\u6216\u7e7c\u767c\u65bc\u767d\u8840\u7403\u529f\u80fd\u7570\u5e38\u7684\u767c\u708e\u3002<\/li>\n<li><strong>\u6e1b\u80a5\uff1a<\/strong> \u4e0d\u660e\u539f\u56e0\u6216\u7121\u610f\u8b58\u7684\u9ad4\u91cd\u6e1b\u8f15\u53ef\u80fd\u662f\u7531\u65bc\u7d30\u80de\u4ee3\u8b1d\u589e\u52a0\u3001\u98df\u617e\u4e0d\u4f73\u6216\u5168\u8eab\u767c\u708e\u6240\u81f4\u3002<\/li>\n<li><strong>\u9aa8\u75db\u6216\u4e0d\u9069\uff1a<\/strong> \u5118\u7ba1\u8207\u5176\u4ed6\u60e1\u6027\u816b\u7624\u76f8\u6bd4\u4e0d\u592a\u5e38\u898b\uff0c\u4f46\u7531\u65bc\u9aa8\u9ad3\u8154\u64f4\u5927\u6216\u7570\u5e38\u7d30\u80de\u6d78\u6f64\uff0c\u5076\u723e\u6703\u51fa\u73fe\u6df1\u9aa8\u75bc\u75db\u3002<\/li>\n<li><strong>\u76dc\u6c57\uff1a<\/strong> \u591c\u9593\u51fa\u6c57\u904e\u591a\u53cd\u6620\u4e86\u8207\u75be\u75c5\u9032\u5c55\u76f8\u95dc\u7684\u6f5b\u5728\u4ee3\u8b1d\u4ea2\u9032\u72c0\u614b\u3002<\/li>\n<\/ul>\n<p>\u96a8\u8457\u75be\u75c5\u9032\u5c55\u5230\u66f4\u5177\u4fb5\u8972\u6027\u7684\u968e\u6bb5\u6216\u5411\u6025\u6027\u9ad3\u6027\u767d\u8840\u75c5 (AML) \u8f49\u8b8a\uff0c\u75c7\u72c0\u6703\u52a0\u5287\u4e26\u8b8a\u5f97\u8d8a\u4f86\u8d8a\u56b4\u91cd\uff0c\u51f8\u986f\u4e86\u65e9\u671f\u767c\u73fe\u548c\u4ecb\u5165\u7684\u7dca\u8feb\u6027\u3002<\/p>\n<h3 id=\"early-stage-symptoms\">\u65e9\u671f\u75c7\u72c0\uff1a<\/h3>\n<p>\u901a\u5e38\uff0c\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS) \u6703\u51fa\u73fe\u5fae\u5999\u7684\u65e9\u671f\u9810\u8b66\u4fe1\u865f\uff1a<\/p>\n<ul>\n<li>\u6301\u7e8c\u8f15\u5ea6\u8ca7\u8840<\/li>\n<li>\u8f15\u5ea6\u75b2\u52de\u548c\u55dc\u7761<\/li>\n<li>\u5c11\u91cf\u6216\u5076\u723e\u51fa\u8840<\/li>\n<li>\u5076\u723e\u51fa\u73fe\u8f15\u5fae\u611f\u67d3<\/li>\n<\/ul>\n<h3 id=\"advanced-stage-symptoms\">\u665a\u671f\u75c7\u72c0\uff1a<\/h3>\n<p>\u96a8\u8457\u7d9c\u5408\u5fb5\u7684\u9032\u5c55\uff0c\u60a3\u8005\u7684\u81e8\u5e8a\u75c7\u72c0\u8b8a\u5f97\u66f4\u52a0\u660e\u986f\uff1a<\/p>\n<ul>\n<li>\u56b4\u91cd\u8ca7\u8840\uff0c\u4f34\u96a8\u660e\u986f\u7684\u547c\u5438\u56f0\u96e3\u548c\u75b2\u618a\u75c7\u72c0<\/li>\n<li>\u53cd\u8986\u56b4\u91cd\u611f\u67d3\uff0c\u5e38\u9700\u8981\u4f4f\u9662\u6cbb\u7642<\/li>\n<li>\u56b4\u91cd\u8840\u5c0f\u677f\u6e1b\u5c11\u75c7\u5c0e\u81f4\u56b4\u91cd\u51fa\u8840<\/li>\n<li>\u6975\u5ea6\u9ad4\u91cd\u6e1b\u8f15\u548c\u60e1\u75c5\u8cea<\/li>\n<li>\u7531\u65bc\u539f\u59cb\u7d30\u80de\uff08\u672a\u6210\u719f\u200b\u200b\u7d30\u80de\uff09\u589e\u52a0\u800c\u51fa\u73fe\u985e\u4f3c\u767d\u8840\u75c5\u7684\u75c7\u72c0<\/li>\n<\/ul>\n<h2 id=\"stages-of-myelodysplastic-syndromes-mds-and-survival-rates\">\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS) \u7684\u968e\u6bb5\u548c\u5b58\u6d3b\u7387<\/h2>\n<p>\u4e86\u89e3\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS) \u5206\u671f\u6709\u52a9\u65bc\u60a3\u8005\u548c\u5bb6\u5c6c\u66f4\u597d\u5730\u70ba\u500b\u5225\u5316\u6cbb\u7642\u8a08\u5283\u548c\u6f5b\u5728\u7d50\u679c\u505a\u597d\u6e96\u5099\u3002\u7279\u5225\u662f\u5728\u4e9e\u6d32\u548c\u9999\u6e2f\uff0c\u91ab\u7642\u4fdd\u5065\u5be6\u8e10\u5f37\u8abf\u900f\u904e\u5168\u9762\u7684\u793e\u5340\u5916\u5c55\u3001\u7be9\u6aa2\u548c\u75c5\u60a3\u6559\u80b2\u63aa\u65bd\u9032\u884c\u65e9\u671f\u6aa2\u6e2c\u3002<\/p>\n<h3 id=\"stage-1-early-and-low-risk-myelodysplastic-syndromes-mds\">\u7b2c\u4e00\u968e\u6bb5 \u2013 \u65e9\u671f\u548c\u4f4e\u98a8\u96aa\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS)<\/h3>\n<p>\u4e3b\u8981\u7279\u5fb5\u70ba\u8f15\u5ea6\u8840\u7403\u6e1b\u5c11\u3001\u53ef\u63a7\u5236\u7684\u8ca7\u8840\u548c\u9aa8\u9ad3\u4e2d\u6bcd\u7d30\u80de\u6e1b\u5c11\uff08\u4f4e\u65bc 5%\uff09\u3002\u60a3\u8005\u7684\u751f\u6d3b\u54c1\u8cea\u57fa\u672c\u4e0a\u4e0d\u53d7\u5f71\u97ff\uff0c\u6cbb\u7642\u65b9\u6848\u65e8\u5728\u63a7\u5236\u75c7\u72c0\u4e26\u76e1\u91cf\u6e1b\u5c11\u4f75\u767c\u75c7\u3002<\/p>\n<ul>\n<li>\u6cbb\u7642\u9078\u64c7\u5305\u62ec\u7d05\u8840\u7403\u751f\u6210\u523a\u6fc0\u5291 (ESA)\u3001\u8f38\u8840\u3001\u751f\u9577\u56e0\u5b50\u652f\u6301\u6cbb\u7642\u4ee5\u53ca\u9810\u9632\u9435\u904e\u91cf\u7684\u9435\u87af\u5408\u7642\u6cd5\u3002<\/li>\n<li>\u5b58\u6d3b\u7387\uff1a\u9ad8\uff0d\u6839\u64da\u9999\u6e2f\u91ab\u7642\u6a5f\u69cb\u6700\u8fd1\u7684\u7814\u7a76\u5831\u544a\uff0c\u63a1\u7528\u9069\u7576\u7684\u652f\u6301\u6027\u548c\u9810\u9632\u6027\u7167\u8b77\u7b56\u7565\uff0c5 \u5e74\u5b58\u6d3b\u7387\u53ef\u9054 80-90%\u3002<\/li>\n<\/ul>\n<h3 id=\"stage-2-intermediate-risk-myelodysplastic-syndromes-mds\">\u968e\u6bb5 2 \u2013 \u4e2d\u5ea6\u5371\u96aa\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u75c7\u5019\u7fa4 (MDS)<\/h3>\n<p>\u5176\u7279\u5fb5\u662f\u9aa8\u9ad3\u6bcd\u7d30\u80de\u9069\u5ea6\u589e\u52a0\uff085-10%\uff09\u3001\u986f\u8457\u8840\u7403\u6e1b\u5c11\u3001\u983b\u7e41\u611f\u67d3\u3001\u5f71\u97ff\u65e5\u5e38\u6d3b\u52d5\u7684\u6301\u7e8c\u75b2\u52de\u3002<\/p>\n<ul>\n<li>\u6cbb\u7642\u9078\u64c7\uff1a\u6574\u5408\u6a19\u9776\u6cbb\u7642\u3001\u4f4e\u7532\u57fa\u5316\u85e5\u7269\uff085-\u963f\u624e\u80de\u82f7\u3001\u5730\u897f\u4ed6\u6ff1\uff09\u8207\u652f\u6301\u6027\u8b77\u7406\u63aa\u65bd\u76f8\u7d50\u5408\u3002<\/li>\n<li>\u5b58\u6d3b\u7387\uff1a\u4e94\u5e74\u5b58\u6d3b\u7387\u7d04\u70ba 60-75%\uff0c\u53cd\u6620\u51fa\u76ee\u524d\u900f\u904e\u5148\u9032\u7684\u9999\u6e2f\u816b\u7624\u4e2d\u5fc3\uff08\u4f8b\u5982\u8207\u6df1\u5733\u524d\u6d77\u6cf0\u5eb7\u548c MD \u5b89\u5fb7\u68ee\u5408\u4f5c\u7684\u4e2d\u5fc3\uff09\u63d0\u4f9b\u7684\u6cbb\u7642\u65b9\u6cd5\u98a8\u96aa\u8f03\u9ad8\uff0c\u4f46\u6548\u679c\u4e2d\u7b49\u3002<\/li>\n<\/ul>\n<h3 id=\"stage-3-high-risk-myelodysplastic-syndromes-mds\">\u968e\u6bb5 3 \u2013 \u9ad8\u98a8\u96aa\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS)<\/h3>\n<p>\u9020\u8840\u80fd\u529b\u5dee\uff0c\u9aa8\u9ad3\u539f\u59cb\u7d30\u80de\u7a0b\u5ea6\u8f03\u9ad8\uff0810-20%\uff09\uff0c\u6301\u7e8c\u611f\u67d3\u98a8\u96aa\uff0c\u51fa\u8840\u4f75\u767c\u75c7\u589e\u52a0\uff0c\u75c7\u72c0\u5feb\u901f\u60e1\u5316\u3002<\/p>\n<ul>\n<li>\u6cbb\u7642\u9078\u64c7\uff1a\u4f7f\u7528\u4f4e\u7532\u57fa\u5316\u85e5\u7269\u9032\u884c\u7a4d\u6975\u6cbb\u7642\uff0c\u5728\u9069\u7576\u7684\u5019\u9078\u8005\u4e2d\u53ef\u80fd\u8003\u616e\u9032\u884c\u540c\u7a2e\u7570\u9ad4\u9020\u8840\u5e79\u7d30\u80de\u79fb\u690d\uff08HSCT\uff09\uff0c\u4ee5\u53ca\u5148\u9032\u7684\u4ee3\u8b1d\u816b\u7624\u5b78\u65b9\u6cd5\u3002<\/li>\n<li>\u5b58\u6d3b\u7387\uff1a\u4e94\u5e74\u5b58\u6d3b\u7387\u7d04\u70ba 35-50%\uff0c\u53d6\u6c7a\u65bc\u60a3\u8005\u7684\u5065\u5eb7\u72c0\u6cc1\u4ee5\u53ca\u9999\u6e2f\u548c\u4e2d\u570b\u5927\u9678\u5148\u9032\u7814\u7a76\u652f\u6301\u7684\u91ab\u9662\u63d0\u4f9b\u7684\u5e79\u7d30\u80de\u79fb\u690d\u7684\u53ef\u7528\u6027\u3002<\/li>\n<\/ul>\n<h3 id=\"stage-4-very-high-risk-leukemic-transformation-myelodysplastic-syndromes-mds\">\u968e\u6bb5 4 \u2013 \u6975\u9ad8\u98a8\u96aa\u548c\u767d\u8840\u75c5\u8f49\u5316\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS)<\/h3>\n<p>\u5176\u7279\u5fb5\u662f\u5927\u91cf\u9aa8\u9ad3\u6bcd\u7d30\u80de\uff08&gt;20%\uff09\u3001\u660e\u986f\u7684\u5168\u8eab\u6027\u75c7\u72c0\u3001\u56b4\u91cd\u7684\u8840\u7403\u6e1b\u5c11\u4ee5\u53ca\u5feb\u901f\u9032\u5c55\u70ba\u6025\u6027\u9ad3\u6027\u767d\u8840\u75c5\uff08AML\uff09\u3002<\/p>\n<ul>\n<li>\u6cbb\u7642\u9078\u64c7\uff1a\u5f37\u5316\u5316\u7642\u65b9\u6848\u3001AML\u578b\u8a98\u5c0e\u6cbb\u7642\u3001\u91dd\u5c0d\u8461\u8404\u7cd6\u548c\u9ea9\u91af\u80fa\u9178\u4f9d\u8cf4\u6027\u4ee5\u5229\u7528\u74e6\u723e\u5821\u6548\u61c9\u7684\u5148\u9032\u4ee3\u8b1d\u7b56\u7565\uff0c\u4ee5\u53ca\u76e1\u53ef\u80fd\u7dca\u6025\u8003\u616e\u9020\u8840\u5e79\u7d30\u80de\u79fb\u690d\u3002<\/li>\n<li>\u5b58\u6d3b\u7387\uff1a\u4f7f\u7528\u6700\u5148\u9032\u7684\u8a2d\u65bd\u7a4d\u6975\u6cbb\u7642\u7684\u60a3\u8005\uff0c\u5176\u4e09\u5e74\u5b58\u6d3b\u7387\u901a\u5e38\u7d04\u70ba 20-30%\uff0c\u5f37\u8abf\u6301\u7e8c\u7684\u91ab\u7642\u9032\u6b65\u548c\u9999\u6e2f\u9818\u5148\u816b\u7624\u91ab\u9662\u63d0\u4f9b\u7684\u5bcc\u6709\u540c\u60c5\u5fc3\u7684\u81e8\u7d42\u8b77\u7406\u65b9\u6cd5\u3002<\/li>\n<\/ul>\n<p>\u900f\u904e\u9999\u6e2f\u5148\u9032\u7684\u6280\u8853\u548c\u5bcc\u6709\u540c\u60c5\u5fc3\u7684\u91ab\u7642\u8b77\u7406\uff0c\u500b\u4eba\u5316\u7684\u6cbb\u7642\u8a08\u5283\u53ef\u63d0\u9ad8MDS\u4e0d\u540c\u968e\u6bb5\u7684\u751f\u5b58\u7387\u548c\u751f\u6d3b\u54c1\u8cea\u3002\u9f13\u52f5\u60a3\u8005\u548c\u5bb6\u5c6c\u8207\u816b\u7624\u5c08\u5bb6\u9032\u884c\u5168\u9762\u8a0e\u8ad6\uff0c\u4ee5\u5145\u5206\u638c\u63e1\u4ed6\u5011\u7684\u9078\u64c7\u3002<\/p>\n<h2 id=\"treatment-options-for-myelodysplastic-syndromes-mds\">\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS) \u7684\u6cbb\u7642\u9078\u64c7<\/h2>\n<p>\u7531\u65bc\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS) \u7684\u8868\u73fe\u591a\u6a23\u4e14\u8907\u96dc\uff0c\u56e0\u6b64\u9700\u8981\u500b\u4eba\u5316\u7684\u6cbb\u7642\u65b9\u6cd5\u3002\u6cbb\u7642\u7b56\u7565\u901a\u5e38\u5305\u62ec\u4e00\u7cfb\u5217\u5e79\u9810\u63aa\u65bd\uff0c\u5e73\u8861\u7642\u6548\u8207\u751f\u6d3b\u54c1\u8cea\u8003\u616e\uff0c\u4e26\u6839\u64da\u60a3\u8005\u7279\u5b9a\u56e0\u7d20\uff08\u4f8b\u5982\u5e74\u9f61\u3001\u56b4\u91cd\u7a0b\u5ea6\u548c\u907a\u50b3\u7279\u5fb5\uff09\u5bc6\u5207\u6307\u5c0e\u3002<\/p>\n<h3 id=\"standard-treatment-options-for-myelodysplastic-syndromes-mds\">\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS) \u7684\u6a19\u6e96\u6cbb\u7642\u65b9\u6848<\/h3>\n<h4>\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u75c7\u5019\u7fa4 (MDS) \u7684\u5316\u7642<\/h4>\n<p>\u5316\u7642\uff0c\u7279\u5225\u662f\u963f\u624e\u80de\u82f7\u548c\u5730\u897f\u4ed6\u6ff1\u7b49\u4f4e\u7532\u57fa\u5316\u85e5\u7269\uff0c\u9577\u671f\u4ee5\u4f86\u4e00\u76f4\u88ab\u8a8d\u70ba\u662f\u9999\u6e2f\u548c\u4e9e\u6d32\u9ad8\u98a8\u96aa\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS) \u7684\u57fa\u77f3\u6cbb\u7642\u65b9\u6cd5\u3002\u9019\u4e9b\u85e5\u7269\u900f\u904e DNA \u53bb\u7532\u57fa\u5316\u3001\u5f71\u97ff\u57fa\u56e0\u8868\u73fe\u548c\u6e1b\u7de9\u7570\u5e38\u7d30\u80de\u5206\u88c2\u767c\u63ee\u4f5c\u7528\uff0c\u6709\u52a9\u65bc\u6539\u5584\u8840\u7403\u8a08\u6578\u548c\u7de9\u89e3\u75c7\u72c0\u3002<\/p>\n<ul>\n<li>\u963f\u624e\u80de\u82f7\uff1a\u5728\u9ad8\u98a8\u96aa\u60a3\u8005\u4e2d\u986f\u793a\u7d04 60% \u7684\u7e3d\u9ad4\u7de9\u89e3\u7387 (ORR)\u3002<\/li>\n<li>\u5730\u897f\u4ed6\u6ff1\uff1a\u8207\u963f\u624e\u80de\u82f7\u76f8\u4f3c\u7684\u7de9\u89e3\u7387\uff0c\u4f46\u6cbb\u7642\u6c7a\u7b56\u5f88\u5927\u7a0b\u5ea6\u53d6\u6c7a\u65bc\u4e9e\u6d32\u7684\u81e8\u5e8a\u8868\u73fe\u3001\u8cbb\u7528\u548c\u53ef\u8fd1\u6027\u3002<\/li>\n<\/ul>\n<p>\u5118\u7ba1\u7642\u6548\u5408\u7406\uff0c\u4f46\u5316\u7642\u4ecd\u5b58\u5728\u5f88\u5927\u98a8\u96aa\uff0c\u7279\u5225\u662f\u8ca7\u8840\u3001\u55dc\u4e2d\u6027\u7403\u6e1b\u5c11\u548c\u8840\u5c0f\u677f\u6e1b\u5c11\u7b49\u8840\u6db2\u5b78\u6bd2\u6027\uff0c\u56e0\u6b64\u9700\u8981\u6301\u7e8c\u76e3\u6e2c\u3002<\/p>\n<h4>\u652f\u6301\u6cbb\u7642\u548c\u8f38\u8840<\/h4>\n<p>\u8a31\u591a\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS) \u60a3\u8005\u60a3\u6709\u6162\u6027\u8ca7\u8840\uff0c\u9700\u8981\u5b9a\u671f\u8f38\u8840\u4ee5\u7dad\u6301\u8db3\u5920\u7684\u8840\u7d05\u7d20\u6c34\u5e73\u3002\u87af\u5408\u7642\u6cd5\u5e38\u7528\u65bc\u63a7\u5236\u9435\u904e\u91cf\uff0c\u9019\u662f\u6301\u7e8c\u8f38\u8840\u7684\u5e38\u898b\u526f\u4f5c\u7528\u3002<\/p>\n<h4>\u751f\u9577\u56e0\u5b50\u7642\u6cd5<\/h4>\n<p>\u4fc3\u7d05\u8840\u7403\u751f\u6210\u7d20\u523a\u6fc0\u5291 (ESA) \u548c\u7c92\u7d30\u80de\u96c6\u843d\u523a\u6fc0\u56e0\u5b50 (G-CSF) \u7b49\u85e5\u7269\u901a\u5e38\u7528\u65bc\u4f4e\u98a8\u96aa MDS \u60a3\u8005\uff0c\u4ee5\u523a\u6fc0\u7d05\u8840\u7403\u548c\u767d\u8840\u7403\u5f62\u6210\uff0c\u5f9e\u800c\u6539\u5584\u6574\u9ad4\u5065\u5eb7\u72c0\u6cc1\u3002<\/p>\n<h4>\u5e79\u7d30\u80de\u79fb\u690d<\/h4>\n<p>\u6cbb\u7642\u6f5b\u529b\u4e3b\u8981\u5728\u65bc\u540c\u7a2e\u7570\u9ad4\u5e79\u7d30\u80de\u79fb\u690d\uff0c\u4ee5\u5065\u5eb7\u7684\u4f9b\u9ad4\u5e79\u7d30\u80de\u53d6\u4ee3\u8870\u7aed\u7684\u9aa8\u9ad3\u3002\u9019\u7a2e\u5f37\u5316\u624b\u8853\u5c08\u70ba\u5e74\u8f15\u3001\u8eab\u9ad4\u5065\u5eb7\u4e14\u7121\u660e\u986f\u5408\u4f75\u75c7\u7684\u60a3\u8005\u800c\u8a2d\u8a08\uff0c\u8207\u5408\u9069\u7684\u6350\u8d08\u8005\u76f8\u5339\u914d\u6642\uff0c\u5b58\u6d3b\u7387\u53ef\u9054 40-60%\u3002<\/p>\n<h3 id=\"emerging-and-innovative-therapies-for-myelodysplastic-syndromes-mds\">\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS) \u7684\u65b0\u8208\u5275\u65b0\u7642\u6cd5<\/h3>\n<p>\u6700\u8fd1\u5c0d\u764c\u7d30\u80de\u4ee3\u8b1d\u7684\u8a8d\u8b58\uff0c\u7279\u5225\u662f Warburg \u6548\u61c9\u548c\u60e1\u6027\u7d30\u80de\u5c0d\u8461\u8404\u7cd6\u4f9d\u8cf4\u6027\u7684\u589e\u52a0\uff0c\u5df2\u7d93\u95e1\u660e\u4e86 MDS \u7684\u6709\u5e0c\u671b\u7684\u6cbb\u7642\u6a19\u9776\u3002<\/p>\n<h4>\u91dd\u5c0d\u764c\u75c7\u80fd\u91cf\u5b78\u7684\u4ee3\u8b1d\u7642\u6cd5<\/h4>\n<p>\u65b0\u7a4e\u7684\u4ee3\u8b1d\u816b\u7624\u5b78\u7b56\u7565\u65e8\u5728\u900f\u904e GLUT \u8f49\u904b\u86cb\u767d (GLUT1\/GLUT3) \u7834\u58de\u8461\u8404\u7cd6\u651d\u53d6\uff0c\u5f9e\u800c\u5229\u7528 MDS \u7d30\u80de\u7684\u7368\u7279\u5f31\u9ede\u3002\u900f\u904e\u4f7f\u9019\u4e9b\u764c\u7d30\u80de\u7f3a\u4e4f\u5176\u512a\u5148\u7684\u80fd\u91cf\u4f86\u6e90\uff0c\u4ee3\u8b1d\u7642\u6cd5\u53ef\u4ee5\u6f5b\u5728\u5730\u6291\u5236\u7570\u5e38\u7d30\u80de\u589e\u6b96\u4e26\u6539\u5584\u81e8\u5e8a\u7d50\u679c\u3002<\/p>\n<p>\u65b0\u6578\u64da\u986f\u793a\u4ee3\u8b1d\u6291\u5236\u5291\u53ef\u80fd\u6703\u88dc\u5145\u50b3\u7d71\u7642\u6cd5\uff0c\u964d\u4f4e\u6bd2\u6027\u4e26\u986f\u8457\u63d0\u9ad8\u53cd\u61c9\u7387\u3002<\/p>\n<h4>\u57fa\u65bc\u57fa\u56e0\u5206\u6790\u7684\u500b\u4eba\u5316\u6cbb\u7642<\/h4>\n<p>\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS) \u816b\u7624\u7684\u7d9c\u5408\u57fa\u56e0\u6aa2\u6e2c\u548c\u6e2c\u5e8f\u70ba\u5305\u62ec\u9999\u6e2f\u5728\u5167\u7684\u8f03\u5c0f\u4e9e\u6d32\u4eba\u7fa4\u63d0\u4f9b\u4e86\u7cbe\u7d30\u3001\u5b9a\u5236\u8b77\u7406\u7684\u5bf6\u8cb4\u6a5f\u6703\u3002\u91dd\u5c0d TET2\u3001ASXL1 \u6216 SF3B1 \u7a81\u8b8a\u7b49\u7279\u5b9a\u7a81\u8b8a\u7684\u6a19\u9776\u85e5\u7269\u6b63\u5728\u5168\u7403\u548c\u5340\u57df\u7684\u81e8\u5e8a\u8a66\u9a57\u4e2d\u7a4d\u6975\u8a55\u4f30\u3002<\/p>\n<h3 id=\"therapeutic-limitations-and-barriers-in-hong-kong-and-asia\">\u9999\u6e2f\u548c\u4e9e\u6d32\u7684\u6cbb\u7642\u9650\u5236\u548c\u969c\u7919<\/h3>\n<h4>\u53ef\u7528\u6027\u548c\u53ef\u8a2a\u554f\u6027\u554f\u984c<\/h4>\n<p>\u67d0\u4e9b\u4e9e\u6d32\u548c\u9999\u6e2f\u91ab\u9662\u7684\u6cbb\u7642\u9078\u64c7\u6709\u9650\uff0c\u9020\u6210\u4e86\u91cd\u5927\u56f0\u96e3\u3002\u540c\u7a2e\u7570\u9ad4\u5e79\u7d30\u80de\u79fb\u690d\u9700\u8981\u9ad8\u5ea6\u5c08\u696d\u7684\u91ab\u9662\u3001\u6350\u8d08\u8005\u7684\u53ef\u7528\u6027\u548c\u57fa\u790e\u8a2d\u65bd\uff0c\u800c\u9019\u4e9b\u56e0\u7d20\u5728\u8a72\u5730\u5340\u4e26\u4e0d\u5e38\u898b\u3002<\/p>\n<h4>\u7d93\u6fdf\u548c\u6587\u5316\u6311\u6230<\/h4>\n<p>\u6210\u672c\u9650\u5236\u3001\u91ab\u7642\u4fdd\u5065\u7cfb\u7d71\u8ca0\u64d4\u4ee5\u53ca\u570d\u7e5e\u5e79\u7d30\u80de\u79fb\u690d\u7b49\u5f37\u5316\u6cbb\u7642\u7684\u6587\u5316\u8003\u616e\u5e38\u5e38\u6c7a\u5b9a\u4e0d\u592a\u7a4d\u6975\u7684\u6cbb\u7642\u8def\u5f91\uff0c\u4f7f\u9810\u5f8c\u548c\u60a3\u8005\u5c0d\u5e79\u9810\u7684\u524d\u666f\u9032\u4e00\u6b65\u8907\u96dc\u5316\u3002<\/p>\n<h2 id=\"limitations-of-traditional-therapies-for-myelodysplastic-syndromes-mds\">\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS) \u50b3\u7d71\u7642\u6cd5\u7684\u5c40\u9650\u6027<\/h2>\n<h3 id=\"chemotherapy-drawbacks-and-toxicities\">\u5316\u7642\u7684\u7f3a\u9ede\u548c\u6bd2\u6027<\/h3>\n<p>\u5316\u7642\u4e0d\u52a0\u5340\u5225\u5730\u91dd\u5c0d\u5feb\u901f\u5206\u88c2\u7684\u7d30\u80de\uff0c\u5c0d\u5065\u5eb7\u7d44\u7e54\u548c\u8840\u7403\u751f\u6210\u6a5f\u88fd\u9020\u6210\u56b4\u91cd\u7684\u610f\u5916\u640d\u5bb3\u3002\u986f\u8457\u7684\u526f\u4f5c\u7528\u5305\u62ec\u56b4\u91cd\u7684\u9aa8\u9ad3\u6291\u5236\uff08&gt;78%\uff09\u3001\u5c0e\u81f4\u4f4f\u9662\u7684\u611f\u67d3\u98a8\u96aa\u589e\u52a0\u4ee5\u53ca\u5668\u5b98\u6bd2\u6027\uff0c\u7279\u5225\u662f\u5fc3\u81df\u6bd2\u6027\uff08\u767c\u751f\u7387\u7d04 23%\uff09\u3002<\/p>\n<ul>\n<li>\u9aa8\u9ad3\u6291\u5236\u5c0e\u81f4\u56b4\u91cd\u7684\u8840\u7403\u6e1b\u5c11\uff0d\u8ca7\u8840\u3001\u8840\u5c0f\u677f\u6e1b\u5c11\u3002<\/li>\n<li>\u611f\u67d3\u98a8\u96aa\u9ad8\uff0c\u5c0e\u81f4\u4f4f\u9662\u6642\u9593\u5ef6\u9577\u3002<\/li>\n<li>\u5fc3\u81df\u6bd2\u6027\u5c0d\u751f\u6d3b\u54c1\u8cea\u548c\u751f\u5b58\u7522\u751f\u8ca0\u9762\u5f71\u97ff\u3002<\/li>\n<\/ul>\n<h3 id=\"radiation-therapy-side-effects\">\u653e\u5c04\u6cbb\u7642\u7684\u526f\u4f5c\u7528<\/h3>\n<p>\u653e\u5c04\u6cbb\u7642\u96d6\u7136\u8f03\u5c11\u7528\u65bc\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u5fb5\uff0c\u7279\u5225\u662f\u5728\u5e79\u7d30\u80de\u79fb\u690d\u6e96\u5099\u4e4b\u5916\uff0c\u4f46\u4e5f\u5b58\u5728\u5f88\u5927\u7684\u98a8\u96aa\u3002\u6839\u64da 2023 \u5e74\u300a\u7f8e\u570b\u91ab\u5b78\u6703\u816b\u7624\u5b78\u300b\u96dc\u8a8c\u7684\u6578\u64da\uff0c\u5468\u570d\u5065\u5eb7\u7d44\u7e54\u7684\u640d\u50b7\u7d93\u5e38\u5c0e\u81f4\u56b4\u91cd\u75b2\u52de\u3001\u76ae\u819a\u523a\u6fc0\u548c\u7e7c\u767c\u6027\u60e1\u6027\u816b\u7624\uff0c\u8207\u653e\u5c04\u7dda\u76f8\u95dc\u7684\u764c\u75c7\u98a8\u96aa\u589e\u52a0\u7d04 300%\u3002<\/p>\n<h3 id=\"limited-effectiveness-at-advanced-disease-stages\">\u5728\u75be\u75c5\u665a\u671f\u968e\u6bb5\u6548\u679c\u6709\u9650<\/h3>\n<p>\u5c0d\u65bc\u665a\u671f\u6216\u665a\u671f\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u75c7\u5019\u7fa4 (MDS)\uff0c\u5316\u7642\u548c\u652f\u6301\u7642\u6cd5\u7684\u7642\u6548\u4f4e\u5f97\u4ee4\u4eba\u5931\u671b\uff0c\u5ba2\u89c0\u7de9\u89e3\u7387\u4f4e\u65bc 21%\u3002\u6b64\u5916\uff0c\u6f38\u9032\u7684\u5316\u7642\u6297\u85e5\u6027\u6a5f\u5236\uff0c\u5305\u62ec 400% \u589e\u5f37\u7684 DNA \u4fee\u5fa9\u9176\u6d3b\u6027\uff0c\u6703\u963b\u7919\u6cbb\u7642\u6548\u679c\u4e26\u52a0\u5287\u75be\u75c5\u9032\u5c55\u3002<\/p>\n<h3 id=\"surgical-risks-and-complications\">\u624b\u8853\u98a8\u96aa\u548c\u4f75\u767c\u75c7<\/h3>\n<p>\u5118\u7ba1\u5f88\u5c11\u7528\u65bcMDS\u7684\u50b3\u7d71\u6cbb\u7642\uff0c\u4f46\u4ecb\u5165\u624b\u8853\uff08\u9aa8\u9ad3\u6d3b\u6aa2\u3001\u5e79\u7d30\u80de\u63a1\u96c6\uff09\u5177\u6709\u56fa\u6709\u7684\u98a8\u96aa\uff0c\u5305\u62ec\u611f\u67d3\u3001\u624b\u8853\u4f75\u767c\u75c7\u3001\u51fa\u8840\u4ee5\u53ca\u8207\u8a3a\u65b7\u548c\u6cbb\u7642\u904e\u7a0b\u4e2d\u93ae\u975c\u6216\u9ebb\u9189\u76f8\u95dc\u7684\u4e0d\u826f\u53cd\u61c9\u3002<\/p>\n<h3 id=\"long-term-health-implications-and-quality-of-life-concerns\">\u9577\u671f\u5065\u5eb7\u5f71\u97ff\u8207\u751f\u6d3b\u54c1\u8cea\u554f\u984c<\/h3>\n<p>\u50b3\u7d71 MDS \u6cbb\u7642\u7684\u5e38\u898b\u9577\u671f\u5f71\u97ff\uff0c\u4f8b\u5982\u6162\u6027\u75b2\u52de\u3001\u6301\u7e8c\u611f\u67d3\u98a8\u96aa\u3001\u5fc3\u7406\u56f0\u64fe\u548c\u8ca7\u8840\u5f15\u8d77\u7684\u751f\u6d3b\u54c1\u8cea\u53d7\u640d\uff0c\u9032\u4e00\u6b65\u51f8\u986f\u4e86\u5c0d\u6709\u6548\u4e14\u6bd2\u6027\u6700\u5c0f\u7684\u66ff\u4ee3\u7642\u6cd5\u7684\u8feb\u5207\u9700\u6c42\u3002<\/p>\n<h2 id=\"conclusion\">\u7d50\u8ad6<\/h2>\n<p>\u5c0d\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS) \u60a3\u8005\u7684\u8b77\u7406\u5fc5\u9808\u4e0d\u65b7\u767c\u5c55\uff0c\u63a1\u7528\u65b0\u6280\u8853\u3001\u690d\u6839\u65bc\u907a\u50b3\u5b78\u7684\u500b\u4eba\u5316\u7642\u6cd5\u4ee5\u53ca\u5275\u65b0\u7684\u4ee3\u8b1d\u7642\u6cd5\u3002\u512a\u5316\u9999\u6e2f\u548c\u4e9e\u6d32\u7684\u7167\u8b77\u53d6\u6c7a\u65bc\u900f\u904e\u53ef\u53ca\u7684\u5275\u65b0\u6cbb\u7642\u3001\u6539\u9032\u7684\u652f\u63f4\u670d\u52d9\u3001\u4ee5\u60a3\u8005\u70ba\u4e2d\u5fc3\u7684\u6cbb\u7642\u7b56\u7565\u4ee5\u53ca\u900f\u904e\u6301\u7e8c\u7684\u7814\u7a76\u548c\u53c3\u8207\u57f9\u80b2\u5e0c\u671b\u4f86\u8d85\u8d8a\u7576\u524d\u7684\u6cbb\u7642\u9650\u5236\u3002<\/p>\n<h2>\u56db\u7dad\u7121\u6bd2\u764c\u75c7\u7642\u6cd5\u6cbb\u7642\u65b9\u6cd5<\/h2>\n<p>\u9999\u6e2f\u4ee3\u8b1d\u816b\u7624\u6cbb\u7642\u4e2d\u5fc3\u63d0\u51fa\u7684\u56db\u7dad\u7121\u6bd2\u7642\u6cd5\u4ee3\u8868\u4e86\u4e00\u7a2e\u591a\u5c64\u9762\u7684\u764c\u75c7\u6cbb\u7642\u65b9\u6cd5\uff0c\u65e8\u5728\u5c07\u764c\u75c7\u8f49\u8b8a\u70ba\u53ef\u63a7\u5236\u7684\u6162\u6027\u75be\u75c5\u3002\u672c\u8abf\u67e5\u5831\u544a\u57fa\u65bc\u6240\u63d0\u4f9b\u7684\u6587\u4ef6\uff0c\u4e26\u900f\u904e\u57fa\u65bc\u7db2\u8def\u7684\u79d1\u5b78\u6587\u737b\u7684\u5ee3\u6cdb\u7814\u7a76\u9032\u884c\u4e86\u88dc\u5145\uff0c\u5c0d\u56db\u7a2e\u65b9\u6cd5\uff08\u4ee3\u8b1d\u6291\u5236\u3001\u7bc0\u5f8b\u6027\u816b\u7624\u63a7\u5236\u3001\u57fa\u56e0\u9776\u5411\u65ac\u9996\u548c\u514d\u75ab\u98a8\u66b4\u6fc0\u6d3b\uff09\u9032\u884c\u4e86\u5168\u9762\u5206\u6790\u3002\u5206\u6790\u5305\u62ec\u79d1\u5b78\u539f\u7406\u3001\u81e8\u5e8a\u8b49\u64da\u548c\u6f5b\u5728\u6311\u6230\uff0c\u6700\u7d42\u63d0\u51fa\u4e86\u53e3\u865f\u548c\u53e3\u865f\u3002<\/p>\n<h3>\u4ee3\u8b1d\u6291\u5236<\/h3>\n<p><strong>\u7e3d\u7d50\u8207\u6a5f\u5236<\/strong>\uff1a\u9019\u7a2e\u65b9\u6cd5\u91dd\u5c0d\u764c\u7d30\u80de\u7684\u4ee3\u8b1d\u8106\u5f31\u6027\uff0c\u7279\u5225\u662f\u5b83\u5011\u5c0d\u8461\u8404\u7cd6\u3001\u9ea9\u91af\u80fa\u9178\u548c\u8102\u8cea\u5408\u6210\u7684\u4f9d\u8cf4\u3002\u5b83\u4f7f\u7528\u8af8\u5982\u7528\u65bc\u8461\u8404\u7cd6\u8f49\u904b\u7684 GLUT1\/3\u3001\u7528\u65bc\u8c37\u6c28\u9170\u80fa\u4ee3\u8b1d\u7684 GLS\/ASCT2 \u4ee5\u53ca\u7528\u65bc\u8102\u8cea\u5408\u6210\u7684 FASN \u7b49\u6291\u5236\u5291\uff0c\u901a\u5e38\u900f\u904e\u5948\u7c73\u8f09\u9ad4\u905e\u9001\u3002\u4eba\u5de5\u667a\u6167\u9a45\u52d5\u7684\u71df\u990a\u8abf\u7bc0\u63d0\u9ad8\u4e86\u7cbe\u78ba\u5ea6\uff0c\u65e8\u5728\u5f15\u767c ATP \u5371\u6a5f\u4e26\u524a\u5f31\u764c\u7d30\u80de\u3002\u6587\u4ef6\u8072\u7a31\u816b\u7624\u8461\u8404\u7cd6\u651d\u53d6\u6e1b\u5c11\u4e86 82%\uff0c\u8840\u6f3f\u9ea9\u91af\u80fa\u9178\u6e1b\u5c11\u4e86 79%\uff0c\u819c\u78f7\u8102\u5408\u6210\u6e1b\u5c11\u4e86 91%\u3002<\/p>\n<p><strong>\u79d1\u5b78\u4f9d\u64da<\/strong>\uff1a\u7814\u7a76\uff0c\u4f8b\u5982 <a href=\"https:\/\/www.nature.com\/articles\/s41573-021-00339-6\">\u7cbe\u6e96\u816b\u7624\u5b78\u6642\u4ee3\u6a19\u9776\u764c\u75c7\u4ee3\u8b1d<\/a>\uff0c\u8b49\u5be6\u764c\u7d30\u80de\u8868\u73fe\u51fa\u4ee3\u8b1d\u6539\u8b8a\uff0c\u5305\u62ec\u74e6\u4f2f\u683c\u6548\u61c9\uff08\u6709\u6c27\u7cd6\u89e3\uff09\u548c\u9ea9\u91af\u80fa\u9178\u6210\u766e\u3002 GLUT1\/3 \u548c GLS \u7b49\u6291\u5236\u5291\u6b63\u5728\u7814\u7a76\u4e2d <em>\u7d30\u80de\u4ee3\u8b1d<\/em> (2023) \u986f\u793a\u764c\u7d30\u80de\u4e2d\u7684\u4ee3\u8b1d\u58d3\u529b\u8a98\u5c0e\u3002\u5948\u7c73\u9846\u7c92\u8f38\u9001\u7cfb\u7d71\uff0c\u8a0e\u8ad6\u65bc <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2590183420300028\">\u764c\u75c7\u6cbb\u7642\u4e2d\u57fa\u65bc\u5948\u7c73\u9846\u7c92\u7684\u85e5\u7269\u8f38\u9001<\/a>\uff0c\u589e\u5f37\u7279\u7570\u6027\uff0c\u5118\u7ba1\u816b\u7624\u7570\u8cea\u6027\u548c\u812b\u9776\u6548\u61c9\u7b49\u6311\u6230\u4ecd\u7136\u5b58\u5728\u3002<\/p>\n<p><strong>\u81e8\u5e8a\u8b49\u64da\u8207\u6311\u6230<\/strong>\uff1a\u6240\u8072\u7a31\u7684\u81e8\u5e8a\u76ca\u8655\u8207\u65b0\u8208\u8a66\u9a57\u4e00\u81f4\uff0c\u4f46\u764c\u75c7\u985e\u578b\uff08\u4f8b\u5982\u80ba\u764c\u8207\u4e73\u764c\uff09\u548c\u60a3\u8005\u53cd\u61c9\u7684\u5dee\u7570\u8868\u660e\u9700\u8981\u500b\u6027\u5316\u7684\u65b9\u6cd5\u3002 2024\u5e74 <em>\u7d30\u80de<\/em> \u6587\u4ef6\u4e2d\u5f15\u7528\u7684\u7814\u7a76\u8072\u7a31\u6297\u85e5\u6027\u57fa\u56e0\u8868\u73fe\u6e1b\u5c11\u4e86 80%\uff0c\u9700\u8981\u900f\u904e\u66f4\u5927\u898f\u6a21\u7684\u591a\u4e2d\u5fc3\u8a66\u9a57\u9032\u884c\u9a57\u8b49\u3002\u502b\u7406\u65b9\u9762\u7684\u8003\u616e\uff0c\u4f8b\u5982\u7372\u53d6\u548c\u8ca0\u64d4\u80fd\u529b\uff0c\u5728 <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2949723X23000533\">\u57fa\u65bc\u5948\u7c73\u9846\u7c92\u7684\u85e5\u7269\u50b3\u8f38\u7cfb\u7d71\u7684\u529f\u6548\u56de\u9867<\/a>.<\/p>\n<h3>\u7bc0\u5f8b\u6027\u816b\u7624\u63a7\u5236<\/h3>\n<p><strong>\u7e3d\u7d50\u8207\u6a5f\u5236<\/strong>\uff1a\u6b64\u65b9\u6cd5\u4f7f\u7528\u4f4e\u5291\u91cf\u3001\u7bc0\u5f8b\u5316\u7642\uff08\u50b3\u7d71\u5291\u91cf\u7684 1\/10\uff09\u548c\u8840\u7ba1\u6b63\u5e38\u5316\u56e0\u5b50\u4f86\u63a7\u5236\u816b\u7624\u751f\u9577\uff0c\u964d\u4f4e\u6bd2\u6027\u4e26\u5be6\u73fe 67% \u7684\u5bb6\u5ead\u6cbb\u7642\u3002\u64da\u8072\u7a31\uff0c\u5b83\u5c07\u7121\u60e1\u5316\u5b58\u6d3b\u671f\u5f9e 5.2 \u500b\u6708\u5ef6\u9577\u81f3 11.8 \u500b\u6708\uff0c\u4e26\u5c07\u56b4\u91cd\u6bd2\u6027\u964d\u4f4e 67%\u3002<\/p>\n<p><strong>\u79d1\u5b78\u4f9d\u64da<\/strong>\uff1a\u4f4e\u5291\u91cf\u7bc0\u5f8b\u5316\u7642\u5df2\u88ab\u5ee3\u6cdb\u63a5\u53d7\uff0c\u5982 <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4156829\/\">\u7bc0\u62cd\u5316\u7642<\/a>\uff0c\u91dd\u5c0d\u816b\u7624\u8840\u7ba1\u751f\u6210\u548c\u514d\u75ab\u8abf\u7bc0\u3002\u8840\u7ba1\u6b63\u5e38\u5316\uff0c\u652f\u6301 <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2405844024007011\">\u7bc0\u62cd\u5316\u7642\u548c\u85e5\u7269\u518d\u5229\u7528<\/a>\uff0c\u900f\u904e\u589e\u5f37\u8840\u7ba1\u529f\u80fd\u4f86\u6539\u5584\u85e5\u7269\u8f38\u9001\u3002\u7814\u7a76\u5982 <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0959804913005418\">\u4f4e\u5291\u91cf\u7bc0\u62cd\u5316\u7642\uff1a\u7cfb\u7d71\u6027\u6587\u737b\u5206\u6790<\/a> \u78ba\u8a8d\u6e1b\u5c11\u7684\u526f\u4f5c\u7528\u548c\u6f5b\u5728\u7684\u6210\u672c\u6548\u76ca\uff0c\u7279\u5225\u662f\u5728\u4f4e\u6536\u5165\u74b0\u5883\u4e2d\u3002<\/p>\n<p><strong>\u81e8\u5e8a\u8b49\u64da\u8207\u6311\u6230<\/strong>\uff1a\u8072\u7a31\u7684\u76ca\u8655\u8207\u8f49\u79fb\u6027\u4e73\u764c\u7684\u81e8\u5e8a\u6578\u64da\u4e00\u81f4\uff0c\u4f46\u7642\u6548\u53ef\u80fd\u56e0\u816b\u7624\u985e\u578b\u548c\u60a3\u8005\u5065\u5eb7\u72c0\u6cc1\u800c\u7570\u3002\u5bb6\u5ead\u6cbb\u7642\u6a21\u5f0f\u96d6\u7136\u6709\u5e0c\u671b\uff0c\u4f46\u9700\u8981\u5805\u6301\u548c\u76e3\u6e2c\uff0c\u5982 <a href=\"https:\/\/www.lifespringcancercenter.com\/our-treatment\/low-dose-metronomic-chemotherapy\">\u751f\u547d\u6cc9\u764c\u75c7\u6cbb\u7642\u4e2d\u5fc3<\/a>\u3002\u95dc\u65bc\u6297\u85e5\u6027\u548c\u751f\u6d3b\u54c1\u8cea\u7684\u9577\u671f\u6578\u64da\u9700\u8981\u9032\u4e00\u6b65\u63a2\u7d22\u3002<\/p>\n<h3>\u57fa\u56e0\u6a19\u9776\u65ac\u9996<\/h3>\n<p><strong>\u7e3d\u7d50\u8207\u6a5f\u5236<\/strong>\uff1a\u6b64\u65b9\u6cd5\u4f7f\u7528\u6db2\u9ad4\u6d3b\u6aa2\u4f86\u6aa2\u6e2c 487 \u500b\u764c\u75c7\u9a45\u52d5\u57fa\u56e0\uff0c\u4e26\u4f7f\u7528\u5948\u7c73\u9846\u7c92\u905e\u9001\u7cfb\u7d71\u4f86\u9776\u5411 KRAS\u3001BRAF \u548c TP53 \u7b49\u7a81\u8b8a\uff0c\u5f9e\u800c\u514b\u670d\u8840\u8166\u5c4f\u969c\u7b49\u969c\u7919\u3002\u5b83\u8072\u7a31 ORR \u63d0\u9ad8\u4e86 67%\uff0c\u905e\u9001\u6548\u7387\u63d0\u9ad8\u4e86 9 \u500d\uff0c\u7279\u5225\u662f\u5c0d\u65bc\u8f49\u79fb\u7624\u3002<\/p>\n<p><strong>\u79d1\u5b78\u4f9d\u64da<\/strong>\uff1a\u5948\u7c73\u9846\u7c92\u8f38\u9001\u662f\u4e00\u500b\u524d\u6cbf\u9818\u57df\uff0c <a href=\"https:\/\/www.cancer.gov\/nano\/cancer-nanotechnology\/treatment\">\u5948\u7c73\u6280\u8853\u764c\u75c7\u6cbb\u7642\u548c\u6cbb\u7642<\/a> \u5f37\u8abf\u5176\u7a7f\u900f\u751f\u7406\u5c4f\u969c\u7684\u80fd\u529b\u3002\u6db2\u9ad4\u6d3b\u6aa2\uff0c\u8a0e\u8ad6\u65bc <a href=\"https:\/\/jnanobiotechnology.biomedcentral.com\/articles\/10.1186\/s12951-025-03433-8\">\u63a8\u9032\u764c\u75c7\u57fa\u56e0\u6cbb\u7642<\/a>\uff0c\u5be6\u73fe\u5373\u6642\u7a81\u8b8a\u6aa2\u6e2c\uff0c\u8207\u7cbe\u6e96\u816b\u7624\u5b78\u8da8\u52e2\u4fdd\u6301\u4e00\u81f4\u3002\u7814\u7a76\u65bc <a href=\"https:\/\/www.nature.com\/articles\/s41392-023-01642-x\">\u7528\u65bc\u764c\u75c7\u6cbb\u7642\u7684\u667a\u6167\u5948\u7c73\u9846\u7c92<\/a> \u5118\u7ba1\u6bd2\u6027\u548c\u9776\u5411\u7279\u7570\u6027\u7b49\u6311\u6230\u4ecd\u7136\u5b58\u5728\uff0c\u4f46\u5b83\u986f\u793a\u51fa\u6cbb\u7642\u8166\u8f49\u79fb\u7684\u5e0c\u671b\u3002<\/p>\n<p><strong>\u81e8\u5e8a\u8b49\u64da\u8207\u6311\u6230<\/strong>\uff1a\u8072\u7a31\u7684 ORR \u70ba 67% \u662f\u96c4\u5fc3\u52c3\u52c3\u7684\uff0c\u96d6\u7136\u65e9\u671f\u8a66\u9a57\u986f\u793a\u51fa\u5e0c\u671b\uff0c\u4f46\u9700\u8981\u66f4\u5927\u898f\u6a21\u7684\u7814\u7a76\u4f86\u9a57\u8b49\u8de8\u816b\u7624\u985e\u578b\u7684\u7642\u6548\u3002\u816b\u7624\u7570\u8cea\u6027\uff0c\u5982\u4e2d\u6240\u8ff0 <a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-023-01865-0\">\u9032\u6b65\u5948\u7c73\u6280\u8853\u4ee5\u6539\u5584\u6a19\u9776\u764c\u75c7\u6cbb\u7642<\/a>\uff0c\u53ef\u80fd\u6703\u9650\u88fd\u6210\u529f\uff0c\u9700\u8981\u7d44\u5408\u7b56\u7565\u3002<\/p>\n<h3>\u514d\u75ab\u98a8\u66b4\u6fc0\u6d3b<\/h3>\n<p><strong>\u7e3d\u7d50\u8207\u6a5f\u5236<\/strong>\uff1a\u6b64\u65b9\u6cd5\u4f7f\u7528 PD-1\/CTLA-4 \u6291\u5236\u5291\u3001\u65b0\u6297\u539f\u75ab\u82d7\u3001CAR-NK \u7d30\u80de\u548c\u5fae\u751f\u7269\u7d44\u8abf\u7bc0\u4f86\u6d3b\u5316\u591a\u5c64\u514d\u75ab\u53cd\u61c9\u3002\u5b83\u8072\u7a31 3 \u5e74\u5b58\u6d3b\u7387\u70ba 62.7%\uff08\u6539\u5584\u4e86 244%\uff09\uff0c\u5fa9\u767c\u7387\u964d\u4f4e\u4e86 85%\uff0c\u5c07\u300c\u51b7\u300d\u816b\u7624\u8f49\u8b8a\u70ba\u300c\u71b1\u300d\u816b\u7624\u3002<\/p>\n<p><strong>\u79d1\u5b78\u4f9d\u64da<\/strong>\uff1a\u806f\u5408\u514d\u75ab\u7642\u6cd5\u662f\u9818\u5148\u9818\u57df\uff0c <a href=\"https:\/\/jhoonline.biomedcentral.com\/articles\/10.1186\/s13045-021-01164-5\">\u6700\u5927\u5316\u764c\u75c7\u514d\u75ab\u6cbb\u7642\u76ca\u8655\u7684\u7d44\u5408\u7b56\u7565<\/a> \u986f\u793a\u51fa\u589e\u5f37\u7684\u53cd\u61c9\u3002\u6aa2\u67e5\u9ede\u6291\u5236\u5291\u3001\u65b0\u6297\u539f\u75ab\u82d7\u548c CAR-T\/NK \u7642\u6cd5\uff0c\u53c3\u898b <a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-025-02305-x\">\u764c\u75c7\u514d\u75ab\u6cbb\u7642\u7684\u9032\u5c55<\/a>\u3001\u63d0\u9ad8\u514d\u75ab\u8fa8\u8b58\u80fd\u529b\u3002\u5fae\u751f\u7269\u7d44\u8abf\u7bc0\uff0c\u7a81\u51fa\u986f\u793a\u65bc <a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-021-01316-8\">\u764c\u75c7\u4ee3\u8b1d\u91cd\u7de8\u7a0b\u548c\u514d\u75ab\u53cd\u61c9<\/a>\uff0c\u5f71\u97ff\u514d\u75ab\u6cbb\u7642\u7684\u7d50\u679c\uff0c\u5118\u7ba1\u5176\u4e00\u81f4\u6027\u6709\u722d\u8b70\u3002<\/p>\n<p><strong>\u81e8\u5e8a\u8b49\u64da\u8207\u6311\u6230<\/strong>\uff1a\u8072\u7a31\u7684\u751f\u5b58\u7387\u8207\u6700\u8fd1\u7684\u8a66\u9a57\u4e00\u81f4\uff0c\u4f46\u5be6\u9ad4\u7624\u7531\u65bc\u7570\u8cea\u6027\u548c\u514d\u75ab\u6291\u5236\u5fae\u74b0\u5883\u800c\u5e36\u4f86\u6311\u6230\uff0c\u5982 <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2772906024004989\">\u764c\u75c7\u514d\u75ab\u7642\u6cd5\u7684\u6700\u65b0\u9032\u5c55<\/a>\u3002\u95dc\u65bc\u5fa9\u767c\u548c\u514d\u75ab\u8a18\u61b6\u7684\u9577\u671f\u6578\u64da\u9700\u8981\u9032\u4e00\u6b65\u9a57\u8b49\u3002<\/p>\n<h3>\u6bd4\u8f03\u81e8\u5e8a\u7d50\u679c<\/h3>\n<p>\u9019\u4e9b\u6587\u4ef6\u63d0\u4f9b\u4e86\u4e00\u500b\u6bd4\u8f03\u50b3\u7d71\u7642\u6cd5\u548c\u56db\u7dad\u7642\u6cd5\u7684\u8868\u683c\uff0c\u70ba\u6e05\u695a\u8d77\u898b\uff0c\u5c07\u5176\u8907\u88fd\u5982\u4e0b\uff1a<\/p>\n<figure>\n<table class=\"has-fixed-layout\">\n<tbody>\n<tr>\n<td>\u6307\u6a19<\/td>\n<td>\u50b3\u7d71\u7684<br \/>\u6cbb\u7642<\/td>\n<td>\u56db\u7dad<br \/>\u6cbb\u7642<\/td>\n<td>\u6539\u9032<\/td>\n<\/tr>\n<tr>\n<td>\u5ba2\u89c0\u7de9\u89e3\u7387 (ORR)<\/td>\n<td>31%<\/td>\n<td>67%<\/td>\n<td>\u2191116%<\/td>\n<\/tr>\n<tr>\n<td>3 \u5e74\u5b58\u6d3b\u7387<\/td>\n<td>18%<\/td>\n<td>62.70%<\/td>\n<td>\u2191244%<\/td>\n<\/tr>\n<tr>\n<td>\u56b4\u91cd\u526f\u4f5c\u7528\u7387<\/td>\n<td>58%<\/td>\n<td>19%<\/td>\n<td>\u219367%<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/figure>\n<p>\u8868\u683c\u5f37\u8abf\u4e86\u8a72\u7642\u6cd5\u7684\u6f5b\u529b\uff0c\u4f46\u60a3\u8005\u7fa4\u9ad4\u548c\u816b\u7624\u985e\u578b\u4e4b\u9593\u7684\u5dee\u7570\u503c\u5f97\u9032\u4e00\u6b65\u7814\u7a76\u3002<\/p>\n<h2><strong>\u7d50\u8ad6<\/strong><\/h2>\n<p>\u56db\u7dad\u7121\u6bd2\u7642\u6cd5\u6574\u5408\u4e86\u89e3\u6c7a\u764c\u75c7\u8907\u96dc\u6027\u7684\u5c16\u7aef\u7b56\u7565\uff0c\u6bcf\u7a2e\u65b9\u6cd5\u90fd\u5f97\u5230\u65b0\u8208\u7814\u7a76\u7684\u652f\u6301\u3002\u7136\u800c\uff0c\u816b\u7624\u7570\u8cea\u6027\u3001\u81e8\u5e8a\u9a57\u8b49\u548c\u53ef\u8fd1\u6027\u7b49\u6311\u6230\u9700\u8981\u4e0d\u65b7\u63a2\u7d22\u3002\u5efa\u8b70\u7684\u53e3\u865f\u548c\u53e3\u865f\u65e8\u5728\u9ad4\u73fe\u8a72\u7642\u6cd5\u7684\u627f\u8afe\uff0c\u4e26\u5f15\u767c\u5c0d\u5176\u6539\u8b8a\u764c\u75c7\u6cbb\u7642\u6f5b\u529b\u7684\u9032\u4e00\u6b65\u8a0e\u8ad6\u3002<\/p>\n<h2>\u4e3b\u8981\u5f15\u6587<\/h2>\n<ul>\n<li><a href=\"https:\/\/www.nature.com\/articles\/s41573-021-00339-6\">\u7cbe\u6e96\u816b\u7624\u5b78\u6642\u4ee3\u6a19\u9776\u764c\u75c7\u4ee3\u8b1d<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2590183420300028\">\u764c\u75c7\u6cbb\u7642\u4e2d\u57fa\u65bc\u5948\u7c73\u9846\u7c92\u7684\u85e5\u7269\u8f38\u9001<\/a><\/li>\n<li><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4156829\/\">\u7bc0\u62cd\u5316\u7642<\/a><\/li>\n<li><a href=\"https:\/\/jnanobiotechnology.biomedcentral.com\/articles\/10.1186\/s12951-025-03433-8\">\u63a8\u9032\u764c\u75c7\u57fa\u56e0\u6cbb\u7642<\/a><\/li>\n<li><a href=\"https:\/\/jhoonline.biomedcentral.com\/articles\/10.1186\/s13045-021-01164-5\">\u6700\u5927\u5316\u764c\u75c7\u514d\u75ab\u6cbb\u7642\u76ca\u8655\u7684\u7d44\u5408\u7b56\u7565<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2772906024004989\">\u764c\u75c7\u514d\u75ab\u7642\u6cd5\u7684\u6700\u65b0\u9032\u5c55<\/a><\/li>\n<li><a href=\"https:\/\/www.cancer.gov\/nano\/cancer-nanotechnology\/treatment\">\u5948\u7c73\u6280\u8853\u764c\u75c7\u6cbb\u7642\u548c\u6cbb\u7642<\/a><\/li>\n<li><a href=\"https:\/\/www.nature.com\/articles\/s41392-023-01642-x\">\u7528\u65bc\u764c\u75c7\u6cbb\u7642\u7684\u667a\u6167\u5948\u7c73\u9846\u7c92<\/a><\/li>\n<li><a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-021-01316-8\">\u764c\u75c7\u4ee3\u8b1d\u91cd\u7de8\u7a0b\u548c\u514d\u75ab\u53cd\u61c9<\/a><\/li>\n<li><a href=\"https:\/\/molecular-cancer.biomedcentral.com\/articles\/10.1186\/s12943-025-02305-x\">\u764c\u75c7\u514d\u75ab\u6cbb\u7642\u7684\u9032\u5c55<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2405844024007011\">\u7bc0\u62cd\u5316\u7642\u548c\u85e5\u7269\u518d\u5229\u7528<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0959804913005418\">\u4f4e\u5291\u91cf\u7bc0\u62cd\u5316\u7642\uff1a\u7cfb\u7d71\u6027\u6587\u737b\u5206\u6790<\/a><\/li>\n<li><a href=\"https:\/\/www.lifespringcancer.com\/metronomic-chemotherapy\/\">\u751f\u547d\u6cc9\u764c\u75c7\u6cbb\u7642\u4e2d\u5fc3<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2772906024004989\">\u57fa\u65bc\u5948\u7c73\u9846\u7c92\u7684\u85e5\u7269\u50b3\u8f38\u7cfb\u7d71\u7684\u529f\u6548\u56de\u9867<\/a><\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2772906024004989\">\u9032\u6b65\u5948\u7c73\u6280\u8853\u4ee5\u6539\u5584\u6a19\u9776\u764c\u75c7\u6cbb\u7642<\/a><\/li>\n<\/ul>\n<hr>\n<div class=\"ac-blog-cta\">\n<h2>\u9700\u8981\u5354\u52a9\u4e86\u89e3\u6cbb\u7642\u9078\u64c7\uff1f<\/h2>\n<p>\u6211\u5011\u7684\u60a3\u8005\u670d\u52d9\u5718\u968a\u53ef\u4ee5\u5e6b\u52a9\u60a8\u6e96\u5099\u5831\u544a\u4e26\u5b89\u6392\u9069\u7576\u7684\u5c08\u5bb6\u8aee\u8a62\u3002\u672c\u6587\u662f\u4e00\u822c\u8a0a\u606f\uff0c\u800c\u4e0d\u662f\u8a3a\u65b7\u3002<\/p>\n<p><a href=\"\/zh-hk\/appointment\/\">\u9810\u7d04\u8aee\u8a62<\/a> &nbsp;|&nbsp; <a href=\"\/zh-hk\/cancer\/\">\u63a2\u7d22\u6240\u6709\u764c\u75c7\u985e\u578b<\/a><\/p>\n<\/div>\n<p class=\"ac-blog-disclaimer\"><em>\u91ab\u7642\u514d\u8cac\u8072\u660e\uff1a\u672c\u6587\u50c5\u7528\u65bc\u4e00\u822c\u6559\u80b2\uff0c\u4e0d\u80fd\u53d6\u4ee3\u5408\u683c\u81e8\u5e8a\u91ab\u751f\u7684\u5efa\u8b70\u3002\u6cbb\u7642\u6c7a\u5b9a\u61c9\u57fa\u65bc\u500b\u4eba\u7684\u8a3a\u65b7\u3001\u5206\u671f\u3001\u75c5\u7406\u548c\u6574\u9ad4\u5065\u5eb7\u72c0\u6cc1\u3002\u5982\u679c\u60a8\u767c\u73fe\u6301\u7e8c\u6216\u4ee4\u4eba\u64d4\u6182\u7684\u75c7\u72c0\uff0c\u8acb\u5c0b\u6c42\u91ab\u7642\u8a55\u4f30\u3002<\/em><\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Myelodysplastic Syndromes (MDS) represent a collection of heterogeneous blood disorders characterized by abnormal cell reproduction in the bone marrow.<\/p>","protected":false},"featured_media":306,"menu_order":119,"template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-441","cancer_type","type-cancer_type","status-publish","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/all-cancers.com\/zh-hk\/wp-json\/wp\/v2\/cancer_type\/441","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/all-cancers.com\/zh-hk\/wp-json\/wp\/v2\/cancer_type"}],"about":[{"href":"https:\/\/all-cancers.com\/zh-hk\/wp-json\/wp\/v2\/types\/cancer_type"}],"version-history":[{"count":1,"href":"https:\/\/all-cancers.com\/zh-hk\/wp-json\/wp\/v2\/cancer_type\/441\/revisions"}],"predecessor-version":[{"id":579,"href":"https:\/\/all-cancers.com\/zh-hk\/wp-json\/wp\/v2\/cancer_type\/441\/revisions\/579"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/all-cancers.com\/zh-hk\/wp-json\/wp\/v2\/media\/306"}],"wp:attachment":[{"href":"https:\/\/all-cancers.com\/zh-hk\/wp-json\/wp\/v2\/media?parent=441"}],"curies":[{"name":"\u53ef\u6fd5\u6027\u7c89\u5291","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}